Adalat XL

Generic name: nifedipine
Class: Calcium channel blocking agents

What is Adalat XL

Adalat XL is a calcium channel blocker. The structural formula of nifedipine is 3,5-pyridine dicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-dimethyl ester, C17H18N2O6nifedipine.

Nifedipine is a yellow crystalline molecule that is essentially water-insoluble but ethanol soluble. It has a 346.3 molecular weight.

Adalat XLuses

adalat orosAdalat XLis used to treat severe chest discomfort (angina) and excessive blood pressure (hypertension). High blood pressure burdens the heart and arteries. If it persists, the heart and arteries may be damaged. This can cause a stroke, heart failure, or kidney failure. High blood pressure raises the risk of a heart attack. Controlling blood pressure may help prevent these issues.

Adalat Oros


Adalat XL blocks calcium channels. It operates by altering calcium transport into heart and blood vessel cells. As a result, nifedipine relaxes blood arteries, increasing blood flow and decreasing heart workload.

Precautions and warnings

Before using Adalat XL, consult your doctor

The hazards of taking a drug must be evaluated against the benefits. You and your doctor will decide. Considerations for this drug include:


Mention any unexpected or allergic reactions to this or other medicines to your doctor. Tell your doctor if you have allergies to foods, colors, preservatives, or animals. Read the ingredients carefully on non-prescription products.


No studies on the impact of Adalat XL on children’s ages have been done. No evidence of safety or efficacy.


No geriatric-specific issues have been shown in investigations to date, limiting the use of Adalat XL in the elderly. However, elderly people are more prone to age-related renal, liver, or heart problems, necessitating prudence and dose adjustments.

Studies on women show that this medicine presents no harm to the baby when used while nursing.

Medicine interactions

While many medicines should never be used together, others may be used even if an interaction is possible. In certain circumstances, your doctor may alter the dose or take other precautions. It is critical that your doctor knows if you are using any of the following medications. The interactions listed below were chosen for their potential significance and are not all-inclusive.

Contraindications: This drug should not be used with any of the following medicines. Your doctor may adjust the dose or frequency of one or both medications if they are prescribed simultaneously.

Abametapir, Amobarbital
Ceritinib, Clarithromycin
Nelfinavir , Netupitant

Using Adalat XL with any of the following may raise the chance of side effects, but it may be the best treatment for you. Your doctor may adjust the dose or frequency of one or both medications if they are prescribed simultaneously.

Food/tobacco/alcohol interactions

Specific drugs should not be used right before or right after eating certain foods due to possible interactions. Alcohol and tobacco usage may potentially create drug interactions. The interactions listed below were chosen for their potential significance and are not all-inclusive.

Using Adalat XL with any of the following may raise the chance of side effects, but it is not always avoidable. Your doctor may adjust your dose or frequency of usage, or give you particular instructions about food, alcohol, or cigarettes.

Other health issues

Other medical issues may impact the use of this drug. Tell your doctor if you have any other health issues, especially:

Dosage and administration of Adalat XL

Adalat XL 20 tablets

Adalat XL 30 tablets

Adalat XL 60 tablets


Adalat XL side effects

In large controlled studies where adverse reactions were observed spontaneously, there were a lot of adverse reactions but were not usually serious and seldom required the stopping therapy or dose adjustments. The majority of them were the result of the vasodilator effect of Nifedipine capsules.

Adverse Effect Nifedipine capsules (%)
Placebo (%)
Dizziness, lightheadedness, and giddiness 27 15
The sensation of heat and flushing 25 8
Headache 23 20
Weakness 12 10
Nausea, heartburn 11 8
Muscle cramps, tremors 8 3
Peripheral edema 7 1
The mood can change, and anxiety may be present. 7 4
Palpitation 7 5
Dyspnea, cough, and wheezing 6 3
Nasal congestion Sore throat, nasal congestion 6 8

There’s also an extensive uncontrolled situation in more than 2100 patients across the United States. The majority of patients suffered from the vasospastic form of angina pectoris or were resistant to it and about half were also receiving treatment with beta-adrenergic blockers. The most frequently reported adverse incidents included:

Incidence Approximately 10%

Incidence Approximately 5%

Incidence 2% or Less

Incidence Approximately 0.5%

Incidence Less Than 0.5%

Many of these side effects are thought to be related to dose. Peripheral edema was seen in approximately 25 percent of patients who took doses below 60 mg daily and in one patient with a dose of 120 mg daily or more. Hypotension transient, usually moderate to mild in severity, and rarely requiring the stopping therapy, occurred in one patient who took less than 60 mg/day and in one patient who took 120 mg daily or greater.

Very rarely, the introduction of Nifedipine capsules for therapy was related to an increase in pain in the angular region which could be due to hypotension. A temporary loss of vision unilaterally is also a possibility.

Furthermore, more severe adverse events were also observed that were not easily distinguished from the normal history of the illness in the patients. There is a chance that some or all of these events are connected. Myocardial infarction was reported in around 4 percent of patients, while the congestive heart condition or lung edema that occurred was approximately two percent. Conduction disturbances or arrhythmias occur in less than 0.5 percent of patients.

What if I missed dose

If you are missing a dose of this medicine make sure you take it as quickly as you are able. If it’s nearing the time to take the next dose, you can skip the missed dose, and go back to your usual dosage schedule. Do not take double doses.


Keep the medicine in a tightly sealed bottle at room temperatures, and away from moisture, heat, and bright light. Avoid the medicine from freezing.

Keep your items out of children’s reach.

Don’t keep old medicine or medications that are no longer needed.

Consult your physician about what you can do with any medication that you do not make use of


Adalat XL


More details

Always consult your doctor to make sure the information presented on this site is appropriate to your particular situation.

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