Jump To


Generic name: micafungin
Brand name: Mycamine
Dosage form: intravenous powder for injection (100 mg; 50 mg)
Drug class: Echinocandins

Medically reviewed by  A Ras MD.

What is micafungin used for?

Micafungin is a prescription medicine that is used to treat fungal infections. It is used to prevent fungal infections.


Micafungin for injection is a sterile, white lyophilized product for intravenous (IV) infusion that contains micafungin sodium. Micafungin sodium is a semisynthetic lipopeptide (echinocandin) synthesized by a chemical modification of a fermentation product of Coleophoma empetri F-11899. Micafungin inhibits the synthesis of 1, 3-beta-D-glucan, an integral component of the fungal cell wall.

Each single-dose vial contains 50 mg micafungin (equivalent to 50.86 mg micafungin sodium) or 100 mg micafungin (equivalent to 101.73 mg micafungin sodium), 200 mg Lactose monohydrate, with Citric acid anhydrous and/or Sodium hydroxide (used for pH adjustment). Micafungin for injection must be diluted with 0.9% Sodium Chloride Injection, USP, or 5% Dextrose Injection, USP [see Dosage and Administration (2)]. Following reconstitution with 0.9% Sodium Chloride Injection, USP, the resulting pH of the solution is between 5 to 7.

Micafungin sodium is chemically designated as: (3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-3-[3-Amino-1(R)-hydroxy-3-oxopropyl]-6-[1(S),2(S)-dihydroxy-2-(4-hydroxy-3-sulfooxyphenyl)ethyl]-11,20,21,25-tetrahydroxy-15-[1(R)-hydroxyethyl]-26-methyl-18-[4-[5-[4-(pentyloxy)phenyl]isoxazol-3-yl]benzamido]-1,4,7,13,16,22-hexaazatricyclo[,13)]heptacosane-2,5,8,14,17,23-hexaone sodium salt.

The chemical structure of micafungin sodium is:


The empirical/molecular formula is C56H70N9NaO23S and the formula weight is 1292.26.

Micafungin sodium is a light-sensitive, hygroscopic white powder that is freely soluble in water, isotonic sodium chloride solution, N,N-dimethylformamide and dimethylsulfoxide, slightly soluble in methyl alcohol, and practically insoluble in acetonitrile, ethyl alcohol (95%), acetone, diethyl ether and n-hexane.

Before taking micafungin, tell your doctor:

  • If you are allergic to micafungin; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take micafungin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take micafungin?

  • Tell all of your health care providers that you take micafungin. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using micafungin while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is micafungin best taken?

Use micafungin as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are the side effects of micafungin that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
  • Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
  • A fast heartbeat.
  • A heartbeat that does not feel normal.
  • Low blood cell counts have happened with micafungin. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Call your doctor right away if you have signs of infection like fever, chills, or sore throat; any unexplained bruising or bleeding; or if you feel very tired or weak.

What are some other side effects of micafungin?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Upset stomach or throwing up.
  • Diarrhea.
  • Headache.
  • Belly pain.
  • Not able to sleep.
  • Anxiety.
  • Irritation where micafungin is given.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out micafungin?

  • If you need to store micafungin at home, talk with your doctor, nurse, or pharmacist about how to store it.





Micafungin Sodium for Injection 50 mg/vial- Vial Label



Micafungin Sodium for injection 100 mg/vial - Vial Label


Read Next Article

PHP Code Snippets Powered By : XYZScripts.com