Zonegran Dosage
Zonegran Dosage Generic name: zonisamide Drug class: Carbonic anhydrase inhibitor anticonvulsants Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 25 mg, 100 mg Partial seizures [100-600 mg/day PO divided qd-bid] Start: 100 mg PO qd, may incr. by 100 mg/day q2wk; Max: 600 mg/day; Info: doses >400 mg/day rarely more effective; taper dose gradually […]
Zontivity Dosage
Zontivity Dosage Generic name: vorapaxar Drug class: Protease-activated receptor-1 antagonists Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 2.08 mg Thrombotic event prevention [2.08 mg PO qd] Info: for pts w/ MI hx or peripheral arterial dz; give w/ ASA and/or clopidogrel Renal dosing [no adjustment] renal impairment: no adjustment HD/PD: no adjustment; no […]
Zortress Dosage
Zortress Dosage Generic name: everolimus (Zortress) Drug classes: MTOR inhibitors, Selective immunosuppressants Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 0.25 mg, 0.5 mg, 0.75 mg, 1 mg Kidney transplant rejection prophylaxis [0.75 mg PO q12h] Start: ASAP post-transplant; Info: for pts w/ low-mod immunologic risk; part of multi-drug regimen; may adjust dose q4-5 days […]
Zosyn Dosage
Zosyn Dosage Generic name: piperacillin and tazobactam Drug class: Beta-lactamase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Intra-abdominal infections [3.375 g IV q6h x4-7 days] Info: for appendicitis or peritonitis Gynecologic infections [3.375 g IV q6h x7-10 days] Info: for postpartum endometritis or PID Skin/skin structure infections [3.375 g IV […]
ZTlido Dosage
ZTlido Dosage Generic name: Lidocaine Topical System Drug class: Topical anesthetics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: PATCH: 1.8% Special Note [formulation clarification] Info: 1.8% lidocaine topical patch bioequivalent to 5% lidocaine topical patch Post-herpetic neuralgia [apply for up to 12h/day] Max: 3 patches at time, x12h/day; Info: apply to intact skin, cover most […]
Zubsolv Dosage
Zubsolv Dosage Generic name: buprenorphine and naloxone (sublingual tablets) Drug class: Narcotic analgesic combinations Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: SL TAB: 0.7 mg/0.18 mg, 1.4 mg/0.36 mg, 2.9 mg/0.71 mg, 5.7 mg/1.4 mg, 8.6 mg/2.1 mg, 11.4 mg/2.9 mg Restricted Distribution in US Short-acting opioid dependence, induction tx [individualize dose SL […]
Zulresso Dosage
Zulresso Dosage Generic name: brexanolone Drug class: Miscellaneous antidepressants Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Restricted Distribution in US Postpartum depression [30 mcg/kg/h IV x4h, then 60 mcg/kg/h IV x20h, then 90 mcg/kg/h IV x28h, then 60 mcg/kg/h IV x4h, then 30 mcg/kg/h IV x4h] Info: may decr. 90 mcg/kg/h IV x28h […]
Zuplenz Dosage
Zuplenz Dosage Generic name: ondansetron (oral) Brand names: Zofran, Zofran ODT, Zuplenz Drug class: 5HT3 receptor antagonists Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: STRIP: 4 mg, 8 mg Nausea/vomiting prevention, chemo-related [highly-emetogenic chemo] Dose: 24 mg PO x1 30min before chemo; Info: use for single-day chemo regimens [moderately-emetogenic chemo] Dose: 8 mg PO q8h […]
Zydelig Dosage
Zydelig Dosage Generic name: idelalisib Drug class: PI3K inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 100 mg, 150 mg Special Note [uses, dosing may vary] Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments CLL, relapsed [150 mg PO bid] Info: […]
Zyflo Dosage
Zyflo Dosage Generic name: zileuton Drug class: Leukotriene modifiers Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 600 mg Asthma, maintenance tx [600 mg PO qid] Max: 2400 mg/day Renal dosing [no adjustment] renal impairment: no adjustment HD/PD: no adjustment; no supplement Hepatic dosing active hepatic dz/baseline LFTs >3x ULN: contraindicated SRC: NLM .