Zulresso Dosage

Generic name: brexanolone
Drug class: Miscellaneous antidepressants

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  INJ

Restricted Distribution in US

Postpartum depression

[30 mcg/kg/h IV x4h, then 60 mcg/kg/h IV x20h, then 90 mcg/kg/h IV x28h, then 60 mcg/kg/h IV x4h, then 30 mcg/kg/h IV x4h]
Info: may decr. 90 mcg/kg/h IV x28h to 60 mcg/kg/h IV x28h if not tolerated

Renal dosing

eGFR <15: avoid use
HD/PD: not defined

Hepatic dosing

[no adjustment]

 

SRC: NLM .