Atropine eye drops

Dosage form: ophthalmic solution
Drug class: Mydriatics

Brand names

In the U.S.

• AK-Dilate
• AK-Pentolate
• Altafrin
• Atropine Care
• Cycologyl
• Cyclomydril
• Iso Cool
• Homatropaire
• Isopto Atropine
• Isopto Homatropine
• Isopto Hyoscine
• Mydfrin
• Mydral
• Mydriacyl
• Neofrin
• Neo-Synephrine
• Omidria
• Paremyd

Canada

• Ak-Dilate
• Ak-Pentolate
• Atropine
• Atropine-Ak
• Atropine Eye Ointment
• Atropine Oil
• Atropisol
• Minims Phenylephrine Hydrochloride

Atropine eye drops

Atropine eye drops are used for a variety of diseases of eye. They are used before eye tests, before and after eye surgery, and to treat certain eye conditions, such as uveitis or posterior synechiae.

These medicines are only available through your doctor’s prescription.

Before using Atropine eye drops

Allergies

Tell your doctor if you have ever had any unusual or allergic reactions in this group or any other medication. Also tell your healthcare professional if you have any other allergies to certain things, such as food dyes, preservatives, or pets. For unauthorized products, read the label or package ingredients carefully.

Pediatricians

Infants and toddlers and children with white hair or blue eyes may be particularly sensitive to the effects of atropine, homatropine, or scopolamine. This may increase the risk of side effects during treatment. Children should use the low potency of this medicine.

Geriatric

Older people are more sensitive to the effects of atropine, homatropine, or scopolamine. This may increase the risk of side effects during treatment.

Pregnancy

Studies on the effects of pregnancy are not performed on humans or animals. However, these drugs may enter the body.

Breastfeeding

These medicines may be absorbed into the body. Atropine passes into breast milk in very small amounts and can cause side effects, such as rapid heartbeat, fever, or dry skin, in children of nursing mothers who use ophthalmic atropine. It is not known whether homatropine or scopolamine passes into breast milk. Although most drugs enter breast milk in small amounts, most of them can be safely used while breastfeeding. Mothers who are taking one of these medications and who wish to breastfeed should discuss this with their doctor.

Interaction with Drugs

Although some drugs may not be used together at all, in some cases two different drugs may be used together even when contact is possible. In these cases, your doctor may want to change the dose, or other precautionary measures may be required. If you are taking any of these medications, it is very important that your healthcare professional knows if you are taking any of the medications listed below. The following interactions are selected on the basis of your possible value and do not cover everything.

Using medication in this class and any of the following medications is not recommended. Your doctor may decide not to prescribe medication for this class or change some of your medication.

• Aceclofenac
• Acemetacin
• Amtolmetin Guacil
• Aspirin
• Bromfenac
• Bufexamac
• Celecoxib
• Choline Salicylate
• Clonixin
• Clorgyline
• Dexibuprofen
• Dexketoprofen
• Diclofenac
• Diflunisal
• Dihydroergotamine
• Dipyrone
• Droxicam
• Etodolac
• Etofenamate
• Etoricoxib
• Felbinac
• Fenoprofen
• Fepradinol
• Feprazone
• Floctafenine
• Flufenamic Acid
• Flurbiprofen
• Ibuprofen
• Indomethacin
• Iproniazid
• Isocarboxazid
• Ketoprofen
• Linezolid
• Lornoxicam
• Loxoprofen
• Lumiracoxib
• Meclofenamate
• Mefenamic Acid
• Meloxicam
• Morniflumate
• Nabumetone
• Naproxen
• Nepafenac
• Nialamide
• Niflumic Acid
• Nimesulide
• Nimesulide Beta Cyclodextrin
• Oxaprozin
• Oxyphenbutazone
• Parecoxib
• Pentoxifylline
• Phenelzine
• Phenylbutazone
• Piketoprofen
• Piroxicam
• Probenecid
• Procarbazine
• Proglumetacin
• Propyphenazone
• Proquazone
• Rasagiline
• Rofecoxib
• Salicylic Acid
• Salsalate
• Selegiline
• Sodium Salicylate
• Sulfasalazine
• Sulindac
• Tenoxicam
• Tiaprofenic Acid
• Tolfenamic Acid
• Tolmetin
• Tranylcypromine
• Valdecoxib

Using medication in this class and any of the following medications is generally not recommended, but may be necessary in some cases. If both drugs are prescribed together, your doctor may adjust the dosage or the frequency with which you use one or both drugs.

• Abciximab
• Acenocoumarol
• Amifampridine
• Amiloride
• Amineptine
• Amitriptyline
• Amitriptylinoxide
• Amoxapine
• Anagrelide
• Apixaban
• Ardeparin
• Argatroban
• Bemiparin
• Bendroflumethiazide
• Benzthiazide
• Betamethasone
• Betrixaban
• Bivalirudin
• Budesonide
• Bumetanide
• Bupropion
• Cangrelor
• Certoparin
• Chlorothiazide
• Chlorthalidone
• Cilostazol
• Citalopram
• Clomipramine
• Clopamide
• Clopidogrel
• Clozapine
• Cortisone
• Cyclopenthiazide
• Cyclosporine
• Dabigatran Etexilate
• Dalteparin
• Danaparoid
• Deflazacort
• Desipramine
• Desirudin
• Desmopressin
• Desvenlafaxine
• Dexamethasone
• Diazoxide
• Dibenzepin
• Digoxin
• Dipyridamole
• Donepezil
• Dothiepin
• Doxepin
• Duloxetine
• Edoxaban
• Enoxaparin
• Eplerenone
• Epoprostenol
• Eptifibatide
• Erdafitinib
• Ergonovine
• Escitalopram
• Ethacrynic Acid
• Feverfew
• Fluocortolone
• Fluoxetine
• Fluvoxamine
• Fondaparinux
• Furazolidone
• Furosemide
• Ginkgo
• Glucagon
• Glycopyrrolate
• Glycopyrronium Tosylate
• Gossypol
• Heparin
• Hydrochlorothiazide
• Hydrocortisone
• Hydroflumethiazide
• Iloprost
• Imipramine
• Indapamide
• Inotersen
• Iobenguane I 123
• Iobenguane I 131
• Lepirudin
• Levomilnacipran
• Lithium
• Lofepramine
• Meadowsweet
• Melitracen
• Methacholine
• Methotrexate
• Methyclothiazide
• Methylergonovine
• Methylprednisolone
• Metolazone
• Midodrine
• Milnacipran
• Nadroparin
• Nefazodone
• Nortriptyline
• Opipramol
• Paramethasone
• Pargyline
• Parnaparin
• Paroxetine
• Pemetrexed
• Pentosan Polysulfate Sodium
• Phenindione
• Phenprocoumon
• Polythiazide
• Prasugrel
• Prednisolone
• Prednisone
• Protein C
• Protriptyline
• Quetiapine
• Reboxetine
• Revefenacin
• Reviparin
• Rivaroxaban
• Scopolamine
• Secretin Human
• Sertraline
• Sibutramine
• Spironolactone
• Tacrolimus
• Tenofovir Disoproxil Fumarate
• Tianeptine
• Ticagrelor
• Ticlopidine
• Tinzaparin
• Tiotropium
• Tirofiban
• Torsemide
• Trazodone
• Treprostinil
• Triamterene
• Trichlormethiazide
• Trimipramine
• Venlafaxine
• Vilazodone
• Vorapaxar
• Vortioxetine
• Warfarin
• Xipamide

Interaction with food / tobacco / alcohol

Certain medications should not be used during or during meals or eating certain types of foods as there may be side effects. The use of alcohol or tobacco and certain drugs may cause some interactions. Talk to your healthcare professional about using your medicine and diet, alcohol, or tobacco.¶

Other health problems

The presence of other medical problems may affect the use of medication in this class. Be sure to tell your doctor if you have any medical problems, especially:

• Brain damage (in children) or
• Down’s syndrome (Trisomy21) (in children and adults) or
• Glaucoma or
• Other eye diseases or problems or
• Spastic Disorders (in children) —The use of ophthalmic atropine, homatropine, or scopolamine may make the condition worse.

Proper use of Atropine eye drops

This section provides information on the proper use of a number of products containing atropine, homatropine, and scopolamine. It may not be specific to Atropine. Please read carefully.

Using Atropine eye drops of this medicine:

• First, wash your hands. Tilt the head back, pressing your finger slightly against the skin under the lower eyelid, pull the lower eyelid off the eye to create space. Put a tree in this space. Release the eyelid and close the eyes tightly. Do not blink. Keep your eyes closed and apply pressure to the inner corner of your eye with your finger for 2 or 3 minutes to allow the medicine to be absorbed.
• Immediately after using eye drops, wash your hands to remove any medication you may have. If you use baby or baby eye drops, be sure to wash your hands immediately afterward, and do not let any medicine get into your mouth. Additionally, erase any medication that the baby or baby may have accidentally received, including his or her face or eyelids.
• To keep the drug as germ-free as possible, do not touch the applicator’s tip anywhere (including the eye). Also, keep the container tightly closed.

Using this ointment form:

• First, wash your hands. Tilt the head back, pressing your finger slightly against the skin under the lower eyelid, pull the lower eyelid off the eye to create space. Squeeze a small amount of oil into the space. A 1 / 3- to ½; -cm strap (about ⅛-inch for infants and toddlers and ¼-inches for older children and adults) is usually sufficient unless you have been told by your doctor to use a different amount. . Release the eyelid and close the eyes tightly. Keep your eyes closed for 1 or 2 minutes so that the medicine is taken away from the eye.
• Immediately after applying the eye ointment, wash your hands to remove any pores that may be on them. If you use baby or baby eye ointment, be sure to wash your hands immediately afterward, and do not let any medicine get into your mouth. Additionally, erase any medication that the baby or baby may have accidentally received, including his or her face or eyelids.
• To keep the drug as germ-free as possible, do not touch the applicator’s tip anywhere (including the eye). After applying the ointment, wipe the tip of the ointment with a clean tissue and keep the tube tightly closed.

Use this medication only as directed. Do not use more and do not use more often than your doctor advised. Doing so may increase the likelihood that more drugs will be absorbed into the body and the risk of side effects. This is especially important when the drug is used in infants and toddlers, as overdose is very dangerous for infants and toddlers.

Dosing

Dosage in this class will vary from patient to patient. Follow your doctor’s instructions or directions. The following information covers only the average doses of these drugs. If your dose is different, do not change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical condition you are taking.

Atropine

In the form of the ophthalmic oil dose:
With uveitis:
Adults — Apply a small amount of eye oil once or twice a day.
Children — Apply a small amount of eye ointment three times a day.
Eye Exam:
Adults — Use and dosage should be determined by your doctor.
Children — Apply a small amount of eye ointment three times a day for one to three days before the test.

For ophthalmic solution (eye drops) dose form:

With uveitis:

• Adults — Apply one eye drops once or twice a day.
• Children — Apply one eye drops once or three times a day.

Eye Exam:

• Adults — Use and dosage should be determined by your doctor.
• Children — Apply one eye drops twice a day for one to three days before the test.

For ophthalmic solution (Atropine eye drops) dose form:

With uveitis:
Adults and children — Use 1 or 2 drops in the eye two or three times a day.
Eye Exam:
Adults — Apply one or two drops to the eye. It can be repeated every five to ten minutes in two or three doses.
Children — Apply one or two drops in the eye every 10 minutes for two or three doses.
To get scopolamine

For ophthalmic solution (Atropine eye drops) dose form:

With uveitis:
Adults and Children — Apply one eye drops four times a day.
Eye Exam:
Adults — Apply one eye drop one hour before the test.
Children — Apply one eye drop twice a day for two days before the test.
The posterior synechiae:
Adults — Apply one eye drop every 10 minutes for three doses.
Children-Use and dosage should be determined by your doctor.
Use before and after surgery:
Adults and Children — Use one eye four to four times a day.

You missed a dose

If you miss a dose of this medicine, take it as soon as possible. However, when the time for your next dose is approaching, skip the missed dose and return to your regular dosing program. Do not use double doses.

If you miss a dose of this medicine and your dose regimen says:

• One dose per day — Use the missed dose as soon as possible. However, if you do not remember the missed dose until the next day, skip the dose and return to your normal dose schedule. Do not use double doses.
• More than one dose per day — Use the missed dose as soon as possible. However, when the time for your next dose is approaching, skip the missed dose and return to your regular dosing program. Do not use double doses.

Storage

Keep out of the reach of children.

Store the medicine in a sealed container at room temperature, away from heat, humidity, and direct light. Keep it frozen.

Do not store old medicines or medicines that are no longer needed.

Cautionary measures while using Atropine eye drops

After putting this medicine in your eyes:

• Your students will be unusually large and you will have blurred vision, especially in nearby objects. Make sure your vision is clear before you drive, operate machinery, or do anything else that could be dangerous if you are visually impaired.
• Your eyes will be more sensitive to light than usual. Wear sunglasses to protect your eyes from sunlight and other bright lights.

These side effects may continue for a few days after you stop taking the drug. However, check with your doctor if it lasts longer than:

• 14 days if you use atropine.
• 3 days if you use homatropine.
• 7 days if you use scopolamine.

Side effects of Atropine eye drops

Along with its desired side effects, the drug may cause some unwanted side effects. While not all of these side effects are possible, they may require medical attention if they do occur.

See your doctor immediately if any of the following side effects occur:

Symptoms of most drugs are absorbed by the body

• Stability or instability
• confusion or unusual behavior
• dryness of the skin
• rapid or irregular heartbeat
• fever
• sweating or redness of the face
• to see, hear, or hear things that are not there
• skin rash
• vague speech
• swollen stomach in children
• dryness or abnormal dryness of the mouth
• unusual drowsiness, fatigue, or weakness

Some side effects may occur frequently that does not require attention. These side effects may disappear during treatment as your body becomes accustomed to the drug. Also, your healthcare professional may be able to tell you ways to prevent or reduce some of these side effects. Ask your healthcare professional if any of the following side effects persist or worry you or if you have any questions about it:

• Blurred vision
• burns or itching in the eyes
• eye irritation is not present before the use of this drug
• increased sensitivity of the eyes to light
• swelling of the eyelids

Some side effects that are not listed may occur in some patients. If you notice any other side effects, consult your healthcare professional.