Prasugrel (Effient)

Genric Name: prasugrel
Drug class: Platelet aggregation inhibitors

Oral route(Tablet)

Prasugrel 5 mg
Prasugrel 10 mg

Prasugrel may cause severe and occasionally fatal bleeding, which can be fatal. Prasugrel should not be used in patients who are suffering from active bleeding pathologically or an incident of stroke or transient ischemic attack. Some risk factors for bleeding are an overweight body mass of less than 60 kilograms bleeding tendency, and concurrent use of drugs that can increase the chance of bleeding (eg fibrinolytics, warfarin, heparin or long-term consumption of NSAIDs). Prasugrel should not be used in patients aged 75 or more, unless in cases of high-risk (diabetes or a history of myocardial infarction). Don’t begin prasugrel for those who may require urgent CABG or a revascularization procedure, and discontinue the medication at seven days before any procedure. If you can, control bleeding with prasugrel but not discontinue it, because discontinuation within the first few weeks following acute coronary syndrome can increase the chance of sustaining cardiovascular events .

The most commonly used brand name(s)

In the U.S.

Available Dosage Forms:

Therapeutic Class: Platelet Aggregation Inhibitor

Pharmacologic Class: ADP-Induced Aggregation Inhibitor

Prasugrel uses

Prasugrel helps prevent heart attacks, strokes, or any other serious issues that affect your blood vessels or heart. It is administered to patients prior to having the procedure for heart surgery known as the percutaneous coronary procedure (PCI).

A stroke or heart attack can happen due to a blocked blood vessel located in the brain or heart is blocked by blood clots. Prasugrel lowers the risk that a blood clot harmful to health is formed by preventing certain blood cells from sticking together or clumping. Prasugrel could also increase the risk of severe bleeding in some individuals.

Prasugrel is only available with the prescription of your physician.

Prior to using prasugrel, it is recommended to consult your doctor

When deciding whether to take any medicine, the dangers of taking the medicine have to be considered against the benefits it can bring. It is a choice you and your doctor make. When taking prasugrel, these are to be considered


Inform your doctor whether you’ve had an unusual reaction or allergy to prasugrel, or any other medication. Inform your health care doctor if you are suffering from other kinds of allergies, like to dyes, foods preservatives, animals, or dyes. For products that are not prescription-only, you must look over the label or the ingredients on the package carefully.


Studies of the appropriate nature have not been conducted on the relation of age and the effects of prasugrel on the child population. The safety and effectiveness of prasugrel have not been confirmed.


The studies that have been conducted up to now haven’t revealed any geriatric-specific issues that might restrict the use of prasugrel for the older. Due to the toxicity of prasugrel treatment for patients with a history of toxicity who are years old or older is not advised.


There aren’t enough studies on women to determine the risks to babies when using this medication while breastfeeding. Consider the benefits and the risk of using this medication during nursing.

Interactions between medicines

While certain medications should not be taken together In other instances, two medicines can be taken together, even though there is a chance of interaction. In these instances your doctor might decide to adjust the dose or take other precautions if required. If you’re taking prasugrel, it’s particularly important to let your doctor know that they prescribe any one of these drugs mentioned below. These interactions have been chosen based on their potential importance and are not meant to be comprehensive.

If you are taking prasugrel along together with any of the following drugs is not recommended. Your physician may decide to not treat you with this drug or modify any other medication you are taking.

Prasugrel in combination together with any of the following medications is generally not advised however, it is possible to do so in certain situations. If two medicines are prescribed the doctor could alter the dosage or the frequency you take either of the medications.

Prasugrel in conjunction together with the following drugs could cause an increase in the risk of certain adverse effects, however using both medicines could be the most beneficial option for you. If you are prescribed both medicines by your physician, they might alter the dosage or frequency at which you take one or both drugs.

Interactions with alcohol, tobacco, or food

Certain medications shouldn’t be taken during or in conjunction with having food items or eating particular kinds of food as interactions could happen. The use of tobacco or alcohol together with certain medications can result in interactions. Talk with your doctor about the interaction of your medication in conjunction with alcohol, food or tobacco.

Other medical issues

The presence of any other medical conditions can affect the effectiveness of Prasugrel. Be sure to inform your physician if you suffer from any other medical issues particularly:

Properly using the drug prasugrel

Use prasugrel as prescribed by your physician. Don’t take more of it, and don’t use it more frequently and do not take it for longer duration than the doctor has ordered. This could increase the risk of adverse negative effects.

Prasugrel is recommended to be sold with a Medication Manual. Learn and follow these guidelines attentively. Talk to your pharmacist or doctor for any additional concerns.

Prasugrel can be taken in combination with and without meals.


The dosage of prasugrel may be different for each patient. Follow the doctor’s instructions or the instructions in the prescription. This information is the most common doses of Prasugrel. If your dose differs you should not alter it until your doctor instructs you to change it.

The quantity of medicine you consume is contingent on your strength medication. In addition, the number of doses that you are taking each day, the amount of time between doses and the amount of time you use the medication are contingent on the medical issue for which you’re taking the medication.

Missed dose

If you are missing an dose of prasugrel do it as quickly as you can. If it’s nearing the time to take your next dose, avoid the dose you missed and go back to your usual dosage schedule. Do not take double doses.


Keep your items out of reach of children.

Avoid keeping outdated medicines or medications that are no longer needed.

Discuss with your doctor to tell you how to dispose of any medication you don’t make use of.

Keep the medicine in a tightly sealed bottle at room temperatures, and away from moisture, heat and sunlight. Avoid the medicine from freezing.

Place the tablets in their original container.

Use caution when using prasugrel

It is crucial that your doctor monitor your progress every time you visit. This allows your doctor to assess whether the medication is functioning well and decide whether or not you should use the medication. Urine and blood tests could be required to determine unintended adverse effects.

Inform all of your dentists, medical doctors and nurses that you are taking Prasugrel. Prasugrel can increase the risk of bleeding serious during an operation or certain dental procedures. Treatment should stop approximately 7 days prior to the surgery or procedure.

Consult your physician right now if you experience these symptoms: changes in mental health bloody or dark urine, difficulties speaking or speaking, fever, paleness that appears on your skin areas of red on your skin and limbs, weakness, seizures eyes that are yellow or the skin. These are signs of a more serious disease called thrombotic purpura (TTP).

Prasugrel can trigger serious allergic reactions, such as angioedema. Angioedema is a serious condition that requires immediate medical care. Inform your doctor immediately when you experience chest pain as well as an itchy, rash and swelling of the mouth, lips and throat. You may also experience if you have difficulty in breathing or swallowing while you’re taking the medication.

Don’t stop taking the drug prasugrel before consulting your physician first. Doing so could increase the risk of blood clots.

Do not take any other medications in the absence of discussing with your physician. This includes prescription and non-prescription (over-the-counter OTC) medicine, herbal and vitamin supplements.

Prasugrel side effects

In addition to its beneficial effects, medicines can result in unwanted negative effects. While not all adverse effects can occur, if they occur, they might require medical attention.

Consult your physician immediately If any of these negative side effects occur:

More commonly

Less popular

Incidence unknown

Certain side effects can be experienced which usually don’t require medical treatment. These side effects can be eliminated after treatment, as your body adjusts your. Additionally your doctor could be able inform you how to prevent or minimize certain adverse side effects. Consult your doctor in the event that any of these adverse effects persist or are troubling or if there are any questions regarding these:

Less well-known

Other adverse side effects that are that are not listed can also occur in certain patients. If you observe any other side effects, you should consult with your physician.

Consult your physician to seek medical advice on possible side effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.