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Amlodipine

Name of the generic: amlodipine
Class of drugs: Calcium channel blocking agents

Brand Names

  • Katerzia
  • Norvasc

Available Dosage Forms:

  • Suspension
  • Tablet

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Calcium Channel Blocker

Chemical Class: Dihydropyridine

Amlodipine uses for amlodipine

Amlodipine
     Amlodipine

Amlodipine is used as a stand-alone medication or with other medicines to treat the risk of hypertension (high blood pressure) for both children and adults. High blood pressure increases the strain on your heart, arteries and. If it persists for a prolonged period then your heart or arteries could not function as they should. This can cause damage to blood vessels in the heart, brain, and kidneys, leading to stroke, heart failure as well as kidney damage. The reduction in blood pressure may decrease the chance of having strokes as well as heart attacks.

Amlodipine can also be used to treat angina stable and chronic (chest pain) in adults.

Amlodipine can be described as a blocker of calcium channels. It blocks the flow of calcium into veins and cells in the heart as well as blood vessels. The blood vessels are relaxed and decrease blood pressure. A decrease in blood pressure can boost the flow of oxygen and blood to the heart.

Amlodipine is only available on the prescription of your physician.

Before taking amlodipine, consult your doctor.

When you decide to take a medication, the potential risks of using the drug must be considered in relation to the benefits it can bring. This is a decision that you as well as your physician make. Amlodipine can be used for: are to be considered

Allergies

Inform your doctor If you’ve ever experienced any allergic or unusual reaction to amlodipine or other medication. Be sure to inform your health doctor if you are suffering from other allergies, like dyes, foods, or preservatives. You may also be allergic to animals. For non-prescription medications, look over the label or ingredient list carefully.

Pediatric

Studies that are appropriate have not been conducted to determine the connection of age to the effect of amlodipine in order to reduce blood pressure for children less than six years old as well to alleviate the chest discomfort in young children. The safety and effectiveness of amlodipine have not been proven.

Geriatric

The studies that have been conducted up to now haven’t revealed the existence of geriatric-specific issues that hinder the effectiveness of amlodipine among the older. However, older patients tend to develop an age-related liver, kidney or heart conditions that may warrant caution and adjustments to the dosage for patients taking amlodipine.

Breastfeeding

There aren’t enough research studies of women that can determine the risks to babies when using this medication while breastfeeding. Consider the benefits and the risk of using this medication during nursing.

Interactions between medicines

Certain medicines shouldn’t be taken together however, there are instances where two medicines can be combined even though there is a chance of interaction. In these situations, the doctor may decide to alter the dosage, or other precautions could be required. If you’re taking amlodipine it is crucial that you let your physician know there are any drugs that are listed below. The following interactions were chosen based on their potential impact and may not be all-inclusive.

Amlodipine in conjunction in conjunction with any of these medications is generally not recommended, however, it could be necessary in certain situations. If two medicines are prescribed and your doctor recommends a change in the dosage or the frequency at which you take either of the drugs.

  • Abametapir
  • Atazanavir
  • Ceritinib
  • Clarithromycin
  • Clopidogrel
  • Conivaptan
  • Cyclosporine
  • Dantrolene
  • Digoxin
  • Domperidone
  • Droperidol
  • Epirubicin
  • Fexinidazole
  • Fosnetupitant
  • Lacosamide
  • Netupitant
  • Piperaquine
  • Rifampin
  • Ritonavir
  • Simvastatin
  • Tacrolimus
  • Tegafur
  • Telaprevir

Utilizing amlodipine along in conjunction with the following drugs could cause an increased chance of experiencing certain adverse effects, however, having both medicines in combination could be the best option for you. If both medications are prescribed by your doctor, they could alter the dosage or frequency at which you take one or both medications.

Interactions with food, tobacco, and alcohol

Certain medications are not recommended to be taken at or in conjunction with taking food, or eating specific kinds of food as interactions could happen. The use of tobacco or alcohol together with certain medications can create interactions. Talk to your doctor about the interaction of your medication when you are taking it with alcohol, food, or tobacco.

Other medical issues

The presence of medical conditions can affect the effectiveness of amlodipine. Be sure to inform your doctor if there are any other medical issues including:

  • Angina (chest pain) 
  • Heart attack either acute 
  • Heart or blood vessel diseases (eg coronary artery disease) 
  • Hypertension (low blood pressure)–Use with care. This can cause the conditions to worsen.
  • Aortic Stenosis (heart valve issue) 
  • Blood vessel disease or heart attack – Use with care. The side effects could be worsened.
  • Liver disease – Use with cautiousness. The effect may be heightened due to the slow removal of the medication in the human body.

Properly using amlodipine

Use amlodipine only when recommended by your doctor. Do not take more than you need,do not use it more often, and don’t take it for any longer duration than the doctor prescribed.

Alongside using amlodipine treatment for high blood pressure can also involve weight control as well as changes to the kinds of foods you consume, particularly those that are high in sodium (salt). Your doctor will advise you which ones are the most crucial for you. It is recommended to consult your physician prior to changing your diet.

It is vital to follow your prescription exactly as prescribed and make appointments with your physician even when you feel fine.

Keep in mind that amlodipine won’t treat elevated blood pressure however it will help in controlling it. So, it is important to take it according to the directions in the event that you plan to reduce your blood pressure and maintain it. You may have to be taking high blood pressure medications throughout your lifetime. If your blood pressure isn’t controlled and treated properly, it could cause serious health issues like heart failure blood vessel disease kidney disease, strokes, or strokes.

Amlodipine is a medicine that can be taken in combination with or without food. It is taken in the same way every day.

Dosing

The dosage of amlodipine can be different for each patient. Follow your doctor’s prescriptions or the instructions printed on your prescription. This information is only the doses that are typical of amlodipine. If your dose differs don’t alter it unless your physician tells you to change it.

The quantity of medicine you are taking is determined by how strong the medication is. In addition, the number of doses that you are taking each day, the amount of time between doses, as well as the amount of time you use the medication are contingent on the medical issue that you’re treating with the medication.

  • Forms of oral dose (suspension or tablet):
    • For angina (chest pain):
      • Adults: 5-10 milligrams (mg) every day. Your physician may alter the dosage as required. But, the dosage is generally not greater than 10 mg daily.
      • Children–Use and dosage should be determined by your physician.
    • High blood pressure
      • Adults – At the beginning five milligrams (mg) daily. Some patients might be put with 2.5 mg daily. Your physician may alter the dosage as required. But, the dose should typically not higher than 10 mg daily.
      • Children aged 6-17 years age–2.5 or 5 mg daily. Your doctor can alter your dosage if needed. But, the dosage is generally not greater than 5 mg per day.
      • Children who are younger than 6 years old – Use and dosage must be determined by your physician.

Missed dose

If you are missing an amlodipine dose, do it as quickly as you are able. If it’s close to the time for the next dose, you can skip the missed dose and then go back to your usual dose schedule. Do not take double doses.

Avoid taking amlodipine when it is longer than 12 hours since the last dose you took.

Storage

Place the medication in a sealed container that is kept at room temperature and away from moisture, heat, and sunlight. Avoid getting frozen.

Keep your items out of children’s reach.

Don’t keep old medicine or medicines that are no longer required.

Discuss with your doctor what you can do with any medication that you do not make use of.

Amlodipine is a prescription drug.

It is crucial that your physician check your child’s or your own progress during regular visits to ensure that amlodipine’s working in a proper manner. Tests for blood may be required to determine if there are any unwanted negative effects.

Amlodipine could cause angina (chest discomfort) or a heart attack in patients suffering from serious vessels disease. Consult your physician immediately if you experience chest discomfort or pain, rapid or irregular heartbeats nausea or vomiting, discomfort or pain in your muscles, jaw or neck, difficulty breathing or sweating.

Lightheadedness, dizziness, or fainting could also occur particularly if you get up abruptly from lying or sitting in a sitting. If you experience dizziness lay down to ensure you don’t faint. You should then rest for a short time before getting up to stop that dizziness from returning. If you faint, call your doctor right away.

Lightheadedness, dizziness, or fainting could also occur when you exercise or the temperatures are hot. A lot of sweat can lead to the loss of water, which can cause lower blood pressure. Be extra careful when exercising or in hot temperatures.

Talk to your doctor immediately If either you or your kid experience discomfort or tenderness of the stomach area and stools. You may also notice pale or dark urine, a loss of appetite nausea, vomiting or yellow skin or eyes. These may be signs of a liver issue that is serious.

If you’ve been taking amlodipine on a regular basis for a number of weeks, do not suddenly discontinue using it. The abrupt stop could cause chest pain or blood pressure to return or worsen. Consult your physician for the best method to decrease your dosage gradually. taking before you stop completely.

When you take a dose of amlodipine, you might experience headaches that last for a few minutes. It should lessen after taking amlodipine over a period of time. If this problem persists or the headaches are intense, consult with your physician.

In certain patients, tenderness, redness, swelling or even bleeding in gums could be seen soon when treatment with amlodipine initiated. The act of flossing and brushing your teeth regularly as well as massaging your gums could assist in preventing this. Consult your dentist on a regular basis to get the teeth cleaned. Talk to your dentist or doctor for any concerns regarding the proper care of your gums and teeth or if you observe any swelling, tenderness, or bleeding from your gums.

Don’t take any other medications without discussing them with your physician. This includes prescribed or nonprescription (over-the-counter OTC) medicines to control appetite as well as colds, asthma or coughs, hayfever, or sinus-related issues as well as vitamin or herbal supplements.

Amlodipine side effects

In addition to its beneficial effects, medicines can result in unwanted side negative effects. Although not all negative side effects are likely to occur, if they occur, they might require medical attention.

Consult your physician immediately If any of these negative side effects occur:

More commonly

  • The ankles are swelling, as well as the feet

Less popular

  • Breathing difficulty or labored
  • dizziness
  • rapid or irregular, pounding or racing heartbeats or pulse
  • the feeling of warmth
  • facial redness and neck and, occasionally, the upper chest.
  • The chest is tight

Rare

  • Black, tarry stool
  • bleeding gums
  • the skin peels, blisters or peeling
  • blood in the urine, or stool
  • blurred vision
  • burning and itching sensation of numbness, pain, “pins and needles” or tingling sensations
  • chest discomfort or pain
  • chills
  • Skin that is cold and clammy
  • cold sweats
  • confusion
  • cough
  • Dark yellow urine
  • diarrhea
  • dilated neck veins
  • dizziness or lightheadedness while rising from a sitting or lying or lying
  • extra heartbeats
  • extreme fatigue
  • fainting
  • febrile
  • itching on the skin
  • Muscle or joint or muscle
  • A large, hive-like swelling appears on the eyelids, face mouth, lips and throat, hands feet, legs or sexual organs
  • Numbness and tingling in fingers, face, or toes
  • discomfort in the legs, arms, or lower back especially in the calves and heels following the exercise
  • uncomfortable or painful urination
  • blueish, pale, or cold feet, hands, or hands
  • The spots are red or purple and pinpoint on the skin
  • Red, irritated eyes
  • facial redness the neck, face, and sometimes, the chest.
  • Itching, redness, or soreness skin
  • shaking in your hands, arms, legs, or feet
  • Heartbeat irregular or slow
  • sore throat
  • ulcers, sores, or white spots in the mouth or on the lips. the mouth
  • blisters, sores blisters, or sores
  • sudden sweating
  • sweating
  • swelling of the fingers, face feet, face, or lower legs
  • swollen glands
  • The shaking or trembling of feet or hands
  • Instability or awkwardness
  • bleeding or bruising that is unusual
  • unusual fatigue or weakness
  • The pulses are weak or absent from the legs
  • weakening in hands, arms legs, feet, or arms
  • weight gain
  • Skin or eyes with yellow eyes

Incidence unknown

  • Stomach or abdominal pain
  • Stools made of clay
  • difficulties with speaking
  • I’m drooling
  • headache
  • Appetit loss
  • Balance control issues
  • muscle trembling, jerking, or stiffness
  • nausea
  • Rash
  • walking in a shuffle
  • Twisting movements of the body
  • Uncontrolled movements, particularly of the neck, face, and back
  • Bad breath smell
  • Vomiting of blood
  • Yellow eyes or skin

Certain side effects can be experienced but they usually do not require medical treatment. These side effects can disappear after treatment, as the body adapts. Additionally, your health professional could be able to inform you how to avoid or lessen certain adverse effects. Consult your physician for any of these adverse effects that persist or are uncomfortable or if you have questions regarding these:

Less popular

  • Acid or a sour stomach
  • Belching
  • sensation of warmth
  • heartburn
  • indigestion
  • weakening or losing strength 
  • Muscle cramps
  • facial redness and neck and, occasionally, the upper chest.
  • Drowsiness, sleepiness, or unusually tiredness
  • stomach discomfort, upset, or pain

Rare

  • Abnormal dreams
  • anxiety
  • Back discomfort
  • Bad, unusual, or unpleasant (after) taste
  • bleeding gums
  • The skin may blister, crust, irritate itching or reddening of the skin
  • Bloating
  • Bloody nose
  • burning sensation in the stomach or chest
  • burning when urinating
  • dry, burning eyes, or burning
  • change in the color of the treated skin
  • changes in the sense of smell
  • Change in the taste
  • Vision changes
  • constipation
  • continuous buzzing or ringing, or any other unidentified sound within the ears
  • cracked dry, scaly, or cracked skin
  • less sexual desire or performance
  • Depression
  • difficulties swallowing
  • discharge, excessive tearing
  • double vision
  • dry mouth
  • Dryness of the skin
  • Gas or excess air can be found inside the stomach gastric intestines
  • overactive muscular tone
  • Eye discomfort
  • sense of constant motion of oneself or the surrounding
  • the feeling of being out of touch
  • experiencing unusually cold temperatures
  • Dry skin, flushed
  • Fruity breath smell
  • full feeling
  • a general sensation of an illness or discomfort
  • hair loss or thinness of the hair
  • Headache, severe and throbbing
  • hearing loss
  • an increase in appetite
  • more appetite
  • Increased sweating
  • an increase in thirst
  • an increased desire to urinate at night the night
  • more frequent urine production
  • irritability
  • Mund irritation
  • absence of emotion or feeling
  • loose stool
  • Memory loss
  • muscles, stiffness, or muscle pains
  • Tension in the muscles or tightness
  • Muscle weakness
  • Nervousness
  • Pain
  • discomforts in the stomach side, abdomen, or stomach or side, which may radiate into the back
  • passing gas
  • Memory problems
  • Redness and swelling of the gums
  • Redness, pain, or swelling in the eyelid, eyelid, or even the inside the lining of the eyelid
  • anxiety
  • nasal runny nose
  • seeing double
  • feeling of spinning
  • feelings of separation from body or self
  • Unsteady walking and shaking
  • shaking
  • Sneezing
  • stuffy nose
  • sweating
  • swollen joints
  • The stomach area is tender
  • thirst
  • difficulty in keeping or releasing urine
  • Trouble sleep
  • Twirling
  • Uncaring
  • Unexplained weight loss that is not explained
  • instabilities, trembling, or other issues with coordination or muscle control
  •  weight loss

Incidence unknown

  • Breast swelling or breast tenderness can occur for males and females

Other adverse side effects that are not mentioned could also be present in certain patients. If you observe any other side effects, you should consult with your physician.

More details

Always consult your physician to make sure the information presented on this page is applicable to your particular situation.

 

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