Jump To



Generic name: trazodone (TRAZ oh done)
The brand name is Desyrel, Desyrel Dividose Oleptro, Desyrel Dividose
Dosage formats: oral tablet (100 mg 150 mg 300 mg 50 mg)
Class of drugs: Phenylpiperazine antidepressants

What is the term trazodone?


Trazodone is an antidepressant, which is part of a family of medications known as serotonin receptor antagonists and Reuptake inhibitors (SARIs). Although trazodone isn’t an actual part of the selective serotonin reuptake inhibitors (SSRIs) class of antidepressants it does have many of the properties of SSRIs.

Trazodone is used to treat the major depressive disorder.

It could help improve your mood, your appetite, and energy levels in addition to reducing insomnia and anxiety related to depression.

Trazodone is a drug that helps restore the balance of a particular chemical (serotonin) in the brain.


Do not take the drug trazodone in case you have an allergy to it or if you’re being treated with the injection of methylene blue.

Don’t take this medication If you’ve previously had an MAO inhibitor in the last 14 days. A risky drug interaction may happen. MAO inhibitors include isocarboxazid linezolid and phenelzine as well as tranylcypromine and many others.

Many young people are concerned about suicide while using an antidepressant. Your physician will monitor your progress on regular appointments while you are taking trazodone. Your family members and other caregivers must be on the lookout for fluctuations in mood, or symptoms.

Inform your doctor about any new or worsening symptoms to your physician for treatment, including change in behavior or mood such as anxiety, panic attacks, or trouble sleeping. You should also tell your doctor when you are feeling angry, irritable, impulsive, or aggressive. anxious, or hyperactive (mentally and physically) or more depressed or you are thinking about suicide or harming yourself.

Avoid giving this medication to anyone who is younger than 18 years of age without consulting medical professionals. Trazodone is not suitable for use by children.

Before you start taking this medicine, make sure to consult your doctor

Do not take trazodone if you are allergic to it.

Do not take this medicine If you’ve previously taken an MAO inhibitor within the last 14 days. A potentially dangerous interaction with a drug could happen. MAO inhibitors include isocarboxazid linezolid, methylene blue injection the phenelzine, and tranylcypromine as well as other MAO inhibitors.

When you stop taking trazodone you must be patient for at minimum 14 days before beginning taking MAOI.

Consult your physician if are also taking stimulant medicines or opioid medication and herbal supplements or medications for mental illness, depression, or Parkinson’s disease. Also, you may have severe infections, migraines, or for the prevention of nausea or vomiting. A reaction with trazodone can cause a serious health condition known as serotonin syndrome.

To ensure that this medication is appropriate for you, tell your physician if you’ve any of the following:

  • kidney or liver disease;
  • heart disease or a heart attack
  • a bleeding or blood clotting disorder;
  • seizures or epilepsy;
  • narrow-angle glaucoma;
  • long QT syndrome;
  • suicidal or drug-related thoughts suicidal thoughts or addiction to drugs
  • the bipolar disorder (manic depression).

Many young people are prone to thoughts of suicide after they first start taking antidepressants. Your doctor should monitor your progress on a regular basis. Family members or other caregivers should be aware of changes in your symptoms or mood.

The use of trazodone during pregnancy can affect the baby. However, stopping the medication might not be safe for you. Do not take or stop this medication without consulting your physician.

If you’re expecting then your name might be added to the registry for pregnancy to monitor how trazodone affects the infant.

It is not recommended to breastfeed while taking this medication. Consult your physician about any potential risks.

Trazodone is not permitted for use by anyone less than 18 years old.

How to take Trazodone?

Follow the exact dosage of trazodone prescribed by your physician. Follow the instructions on the prescription label and study the entire medication guide or instruction sheets. The doctor might modify your dosage.

Try trazodone in the aftermath of eating or snacking.

It could take as long as two weeks before symptoms begin to improve. Use the medication exactly according to the directions and inform your doctor if you feel your symptoms don’t improve.

It is not recommended to stop taking the medicine abruptly, or you may experience unpleasant side effects (such as vomiting, dizziness, and sweating. Other symptoms include agitation and numbness electric shock symptoms). Consult your physician about how you can completely stop taking this medication.

Keep at room temperature, far from heat, moisture, and light.

Dosing information

Usual Adult Dose for Depression:

Initial dosage 150 mg, orally, every day in divided doses. This can be increased to 50 mg per day orally every 3 or 4 days.
Maximum dose:
-Inpatients: 600 mg/day
-Outpatients: 400 mg/day

Patients should be screened for a family or personal background of bipolar disorder mania or hypomania prior to initiation of treatment.
Patients must be checked for withdrawal symptoms prior to they stop taking their medication.
After an appropriate response has been obtained the dosage can be reduced gradually based on the response to therapy.
If you experience drowsiness it is possible that a significant portion of the daily dose could be administered prior to bedtime or a decrease in dosage might be needed.
This drug is best taken soon after an eating meal or light snack.

How do I deal with it if don’t take the dose?

You should take the medication as quickly as you are able, but avoid your missed dosage if it’s close to the time of the next dose. Don’t have two doses at one time.

How do I react if consume too much?

For medical emergencies, seek medical attention immediately or contact for help at the Poison Help line at 1-800-222-1222. An overdose may be fatal if trazodone is used in conjunction in combination with alcohol, barbiturates, phenobarbital, or sedatives, such as diazepam (Valium).

The symptoms of an overdose can include severe dizziness, vomiting or a penis erection that’s long or painful, fast or pounding heartbeats, seizures (black-out or convulsions), or breathing that becomes more difficult or ceases.

What  to avoid

Don’t drink alcohol. Dangerous side effects or death may occur.

Talk to your doctor prior to using a nonsteroidal anti-inflammatory medication (NSAID) like naproxen, aspirin, ibuprofen, Advil, Aleve, Motrin, and more. Utilizing an NSAID that contains trazodone can cause bleeding or bruises easily.

Avoid driving and other hazardous activities until you understand the effects of this medication on your body. Your reaction could be affected.

Be careful not to get up too fast from lying or sitting in a position. You could be dizzy.

Trazodone side effects

Take immediate medical attention If you are experiencing symptoms of an allergy reaction to the drug trazodone such as asthmatic hives, difficulty breathing, and swelling of your lips, face, or tongue.

Stop taking trazodone, and call your doctor right away when you experience an erection in the penis that’s painful or lasts for 6 hours or more. It could be an emergency medical situation that could result in an extremely serious condition that needs to be addressed by surgery.

Inform your doctor about any new or worsening symptoms to physician including changes in your mood or behavior or panic attacks, anxiety, and trouble sleeping. Also, when you are feeling uncontrollably angry, irritable and aggressive, active, restless (mentally and physically), or depressed, or are contemplating suicide or harming yourself.

Consult your physician immediately If you suffer from:

  • Heartbeats that are fast or rapid, the chest is fluttering as well as breathlessness and abrupt dizziness (like you’re about to pass out);
  • Slow heartbeats;
  • strange thoughts or behaviors;
  • easily bruising, unusual bleeding easy bruising, unusual bleeding
  • Low levels of sodium levels in the body headache dizziness, confusion, slurred speech severe weakness, vomiting, and loss of coordination. feeling unstable.

Get medical attention now if you are experiencing signs of the serotonin-related syndromes, like hallucinations, agitation, sweating, and shivering. You may also experience a rapid heart rate muscle stiffness or twitching. Also, you may experience loss of coordination nausea, vomiting, or diarrhea.

Common side effects of trazodone are:

  • drowsiness, dizziness, tiredness;
  • swelling;
  • weight loss;
  • blurred vision
  • diarrhea, constipation; or
  • stuffy nose.

This isn’t a complete list of possible side effects, and other side effects could be present. Contact your doctor for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

What other medications can have an effect on the effects of trazodone?

Utilizing trazodone in conjunction with other medications which cause drowsiness can cause more of this. Consult your physician before taking opioids, a sleeping pill,s or a muscle relaxer, or medication for seizures or anxiety.

Discuss with your doctor all the medications you take. There are many drugs that can interact with trazodone. This is especially true for:

  • Other antidepressants,
  • phenytoin;
  • St. John’s wort;
  • tramadol;
  • diuretic, also known as “water pill”;
  • medications to treat mood disorders or mental illnesses such as schizophrenia.
  • a blood thinner warfarin Coumadin, Jantoven; or
  • migraine headache medication migraine headache medicine sumatriptan, Imitrex, Maxalt, Treximet, and other medications.

This list isn’t complete and a variety of other medications could be incompatible with trazodone. This includes prescription and over-the counter supplements, vitamins, as well as herbal products. The list of possible drug interactions is not exhaustive. are listed here.

Read Next Article

PHP Code Snippets Powered By : XYZScripts.com