Jump To



Generic name: Rasagiline 
The brand name is Azilect
Class of drugs: Dopaminergic anti parkinsonism agents

What is Rasagiline?


Rasagiline is a drug that increases the amounts of certain chemicals within the brain.

Rasagiline is a treatment for signs of Parkinson’s illness (stiffness as well as tremors, spasms, and poor control of muscles).

Rasagiline may be combined alongside another medication called levodopa.


Do not take Rasagiline if previously used any MAO-inhibitor within the last 14 days, like linezolid, isocarboxazid or methylene blue injections, phenelzine selegiline or tranylcypromine.

Inform your doctor of the medicines you’ve used during the two weeks prior to when you begin taking Rasagiline. A variety of drugs may react with rasagiline, and certain drugs shouldn’t be used in conjunction with each other.

Before taking this medicine consult your physician that you suffer from liver problems.

There are a variety of other medications which can trigger serious health issues if taken along with Rasagiline. Discuss with your physician any medications you take. This includes prescriptions, over-the-counter or vitamin as well as herbal products. Don’t begin any new medication without consulting your physician. Keep a record of all the medications you take and give it to any health professional who cares for you.

If you’re taking this medication and for a period of 2 weeks after you have stopped taking it you might not be able to consume certain kinds of cheese. Follow the instructions of your doctor. Rasagiline can affect your thinking or reaction. Be cautious when driving or doing things that require you to be aware.

Before you start taking this medicine, make sure to consult your doctor.

It is not recommended to use Rasagiline If you are allergic to rasagiline.

Don’t use Rasagiline in the event that you’ve used another MAO-inhibitors within the last 14 days. A risky drug interaction may be triggered. MAO inhibitors are isocarboxazid linezolid, methylene blue injection selegiline, phenelzine and more.

Many medications can be in a relationship and can cause harmful adverse effects. Certain medications shouldn’t be combined in conjunction with Rasagiline. Your doctor could alter your treatment regimen in the event that you also take:

  • cyclobenzaprine (a muscle relaxer);
  • dextromethorphan (contained in a number of over-the-counter cough medicine);
  • meperidine (Demerol);
  • methadone;
  • St. John’s Wort; or
  • tramadol (UltramUltracet).

Check with your physician whether you are also taking medications that are stimulants, opioids, herbal products as well as medicines to treat depression or psychological illness migraine headaches and serious infections or to prevent vomiting and nausea. These medications may interfere with rasagiline and create an extremely serious condition known as serotonin syndrome..

To ensure that Rasagiline is suitable for you, ask your physician if you’ve ever experienced:

  • blood pressure, blood pressure or lower blood pressure;
  • kidney or liver disease and
  • if you take ciprofloxacin (an antibiotic).

People with Parkinson’s disease might be at a greater risk for skin cancer ( melanoma). Consult your physician about any warning signs for skin that you should be aware of.

It isn’t known if this medicine could affect a newborn baby. Inform your doctor if are expecting or planning to be pregnant.

It is not recommended to breastfeed while taking this medication. Talk to your doctor regarding any risks.

How to take the Rasagiline?

Use Rasagiline exactly as directed by your physician. Follow the instructions on the label of your prescription and study the entire medication guide or instruction sheets. The doctor might alter your dosage.

If you’re taking Rasagiline by itself, the dosage could be different from the dose you receive when taking it along together with other Parkinson’s drugs. Follow the instructions of your doctor for dosage with care.

Rasagiline could be a part of a full program of treatment that includes a specific diet. Follow the diet plan developed specifically for you by your physician or nutritionist.

Learn about this list of food items that you must stay clear of to avoid certain adverse effects associated with rasagiline.

Contact your doctor if Parkinson’s symptoms don’t improve or become worse after using Rasagiline.

Place in a cool, dry place far from heat and moisture.

Don’t stop taking Rasagiline abruptly or you may be suffering from withdrawal-related symptoms. Discuss with your doctor the best way to stop taking the medication.

Dosing information

Usual Adult Dose for Parkinson’s Disease:

The recommended dose is 1 mg orally every day

Adjunct therapy:
Dose for the first time (in patients taking concurrent treatment with levodopa): 0.5 mg orally every day, once
The first dose (in patients who are not taking the same medication as levodopa) is 1 mg orally, once daily.
Dosage for maintenance: 0.5 mg to 1 mg taken orally, once per day.

Maximum dosage 1 mg taken orally, every day, once

Comments: Can be used as an adjunct therapy for patients receiving levodopa therapy alongside or without other medicines employed in the treatment of Parkinson’s disease.

What If I mee the dose?

Omit the missed dose,  and take your next dose at the normal time. Don’t take two doses at the same time.

How do I react if consume too much?

For medical emergencies, seek emergency treatment or contact the Poison Help line at 1-800-222-1222. The overdose of rasagiline can cause death.

The symptoms of an overdose could include fatigue, dizziness, severe headache and a rapid pulse. You may also be being irritable or anxious muscles spasms in your jaw or neck sweating as well as clammy or cold skin and breathing that is shallow, fainting or having seizures (convulsions). The symptoms could be delayed for between 12 and 24 hours following an overdose.

What to be aware of?

Avoid driving and other hazardous activities until you are aware of what this medicine can do to you. Drowsiness or dizziness can lead to accidents, falls or even serious injuries. Be careful not to get up too quickly from lying or sitting in a position. You may be dizzy.

Beware of drinking alcohol, specifically vermouth, red wine, tap beers, or ale.

Avoid eating foods high in tyramine like older cheeses, aged fava bean, herring, soy sauce, processed or pickled meats, fish, and other meats that have been dried, aged or smoked or fermented. Tyramine consumption while you take Rasagiline can increase your blood pressure to levels that are dangerous that could lead to dangerous adverse reactions.

Rasagiline adverse consequences

Take immediate medical attention in the event that you exhibit symptoms of an allergy reaction with Rasagiline. Hives or breathing difficulties or swelling of your lips, face and tongue.

Consult your physician immediately If you suffer from:

  • extreme headache severe headache, fuzzy vision, and the pounding your neck or ear;
  • excessive drowsiness or falling asleep quickly even though you feel alert
  • unexpected mood swings or changes in behaviour;
  • hallucinations;
  • A feeling of lightheadedness, as if you’ve passed out or
  • more severe symptoms of Parkinson’s (especially involuntary muscle movements).

Get medical attention immediately when you exhibit indications that suggest serotonin syndrome, for example, hallucinations, agitation, sweating, fever or shivering, an increase in heart rate muscles stiffness and twitching, loss of coordination nausea, vomiting or diarrhea.

Certain people who take Rasagiline with levodopa have been able to fall asleep during their normal routine activities during the day, such as eating, working, talking or driving. Inform your doctor if are experiencing any issues with sleeping through the day or experiencing tiredness.

There is a possibility that you will experience increased sexual urges, unusual cravings towards gambling or any other intense desires while taking this medicine. Consult your physician in the event of this.

Common Rasagiline side effects could include:

  • depression;
  • sleep problems (insomnia), strange dreams;
  • muscles that are involuntary;
  • Loss of appetite reduction in weight;
  • indigestion, stomach pain, nausea, vomiting, constipation;
  • stiffness or joint pain;
  • rash;
  • cough and other flu symptoms;
  • dry mouth or
  • swelling of your feet or hands.

This isn’t a complete list of possible side effects, and other side effects could occur. Contact your doctor to seek medical advice on the effects. You can report any side effects to the FDA at 1-800-FDA-1088.


What other drugs can have an effect on Rasagiline?

Utilizing Rasagiline along with other medicines which cause you to feel drowsy may cause more of this. Talk to your doctor prior to using opioids, a sleeping pill or a muscle relaxer or medication for anxiousness and seizures. Inform your doctor if used an antidepressant in the two weeks prior to when you begin using Rasagiline.

A variety of drugs interfere with rasagiline, and certain medications should not be used together simultaneously. Inform your doctor about your current medications and all medicines you begin or stop taking. This includes prescription and over the counter medicine, vitamins, and herbs. The interactions of these products are not included here.

Additional details

  • Your pharmacist or doctor has more details on Rasagiline.

Be sure to keep this and other medicines out of reach of children. Never let your medications be shared with anyone else and make use of Rasagiline only in the manner that is prescribed.

Always consult your doctor to confirm that the information provided on this page is applicable to your specific situation.

Read Next Article

PHP Code Snippets Powered By : XYZScripts.com