Genric Name: ciprofloxacin
Class of drugs: Quinolones
Oral route(Tablet;Tablet Extended Release; Suspension)
Fluoroquinolones, such as ciprofloxacin are linked to severe and possibly irreparable side effects that may have been observed in combination, such as tendinitis and nerve ruptures, peripheral neuropathy, and CNS consequences. Stop using ciprofloxacin and stay clear of fluoroquinolones for patients suffering from these severe adverse reactions. Limit the use of ciprofloxacin to patients who do not have other treatment options for a simple UTI. Fluoroquinolones, such as ciprofloxacin can cause muscle weakness in patients suffering from Myasthenia Gravis. Avoid in patients who have a history of myasthenia gravis.
Oral route(Suspension; Tablet, Extended Release; Tablet)Fluoroquinolones, such as ciprofloxacin are linked to the grave and disabling negative reactions which have been observed in combination, such as tendinitis and nerve ruptures, peripheral neuropathy, and CNS adverse effects. Do not use ciprofloxacin and refrain from using fluoroquinolones for patients suffering from these severe adverse reactions. Use ciprofloxacin only in patients who are left with no other treatment options in the event of an acute flare-up of chronic sinusitis or acute bronchitis. Fluoroquinolones such as ciprofloxacin Hydrochlor can cause muscle weakness in patients suffering from myasthenia gravis. Avoid in patients who have a history of myasthenia gravis.
In the U.S.
Available Dosage Forms:
- Powder for Suspension
Therapeutic Class: Antibiotic
Chemical Class: Fluoroquinolone
Applications for the drug ciprofloxacin
Ciprofloxacin helps treat infections caused by bacterial strains that affect various areas of the body. Ciprofloxacin liquids for oral use as well as tablets can also be used to treat anthrax infections due to inhalation exposure. Ciprofloxacin can also be used to combat and stop plague (including the septicemic and pneumonic plague). Ciprofloxacin can cause or delay the signs of Syphilis. It’s not effective against syphilis-related infections.
Ciprofloxacin Extended-release tablets are intended for the treatment of urinary tract problems. This includes acute uncomplicated pyelonephritis.
Proquin(r) The XR tablets are used for treating simple or non-complicated Urinary tract infections (acute cystitis).
Ciprofloxacin is part of the class of drugs referred to by the name quinolone-based antibiotics. It is effective in killing bacteria or hindering their growth. However, ciprofloxacin won’t help with colds, flu or any other viruses.
Ciprofloxacin is available only on the prescription of your physician.
Before using ciprofloxacin, make sure you know the following:
In making a decision to take any medicine, the dangers of using the drug must be considered in relation to the positive effects it could bring. This is a decision that you as well as your physician make. For ciprofloxacin: The following are to be considered
Discuss with your physician whether you’ve had any allergic or unusual reaction to ciprofloxacin, or any other medications. Inform your health care specialist if you are suffering from any other kinds of allergies, for example, to dyes, foods preservatives, animals, or dyes. For products that are not prescription-only, you must look over the label or ingredient list carefully.
The studies that have been conducted up to now haven’t revealed issues that are specific to children, which could hinder the efficacy of ciprofloxacin children. However, due to its toxic effects, it should be administered with caution when other treatments were evaluated and proved to be ineffective. Ciprofloxacin is an oral fluid and tablet that can be administered to children to treat anthrax infections in the event of exposure and also to treat kidney diseases.
The right studies haven’t been conducted to determine the connection between age and the effects of the ciprofloxacin extended-release tablet in the children’s population. Safety and efficacy haven’t been proven.
The studies that have been conducted so far have not revealed specific geriatric issues that could hinder the effectiveness of ciprofloxacin among the older. However, patients who are elderly tend to develop issues with their heart or kidneys due to age or suffer from severe tendon issues (including rupture of the tendon) that may warrant cautiousness in patients taking ciprofloxacin.
There aren’t enough studies on women to determine the risks to babies when using this medication while breastfeeding. Consider the benefits and the risks that could be associated with taking this medication when nursing.
Interactions between medicines
Certain medicines shouldn’t be combined in any way In other instances, two medicines can be taken together, even though there is a chance of interaction. In these instances, the doctor may decide to adjust the dose or any other precautions could be required. If you’re taking ciprofloxacin It is crucial to let your healthcare professional be aware that you are using any one of these medications that are listed below. The following interactions were determined based on their potential importance and may not be all-inclusive.
The use of ciprofloxacin along together with the following medications is not advised. Your doctor might choose not to treat you with this drug or alter one of the other medications you are taking.
Combining ciprofloxacin with one of the following drugs is not usually recommended but it is possible in certain circumstances. If the two medications are prescribed and your doctor recommends a change in the dose or the frequency at which you use either of the drugs.
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Cholera Vaccine, Live
- Doxorubicin Hydrochloride Liposome
- Inotuzumab Ozogamicin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glargine, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Magnesium Sulfate
- Mycophenolate Mofetil
- Sirolimus Protein-Bound
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
If you are taking ciprofloxacin together with any of the following medications can result in an increased risk of some adverse reactions, however, having both medicines in combination could be the most effective treatment for you. If you are prescribed both medicines in combination, your physician could alter the dosage or frequency of use of one or both medications.
- Aluminum Carbonate, Basic
- Aluminum Hydroxide
- Aluminum Phosphate
- Aminolevulinic Acid
- Dihydroxyaluminum Aminoacetate
- Dihydroxyaluminum Sodium Carbonate
- Lanthanum Carbonate
- Magnesium Carbonate
- Magnesium Hydroxide
- Magnesium Oxide
- Magnesium Trisilicate
Interactions with alcohol, tobacco, or food
Certain medications shouldn’t be taken during or in conjunction with having food items or eating particular kinds of food, as interactions can happen. Smoking or drinking alcohol in conjunction with certain medications may create interactions. The following interactions were chosen in light of their potential importance and are not intended to be comprehensive.
If you are taking ciprofloxacin along in conjunction with any of the following could result in an increased risk for certain adverse effects, however, they are inevitable in some instances. If you take them together the doctor could change the dosage or frequency you take ciprofloxacin or provide specific guidelines regarding the consumption of food, alcohol, or tobacco.
- Dairy Food
Other medical conditions
The presence of any other medical conditions can affect the usage of ciprofloxacin. Be sure to inform your doctor if there are any other medical issues particularly:
- Aortic aneurysm (bulge within the wall of most important arterial)
- Bradycardia (slow heartbeat)
- History of heart attack
- Heart disease (eg heart failure,)
- Heart rhythm issues (eg long QT interval) or relatives with a history of heart problems
- Hypokalemia (low potassium levels in the blood) not corrected
- Hypomagnesemia (low magnesium levels in the blood), uncorrected
- Liver disease
- Mental disease
- Seizures (epilepsy)
- Stroke, Use with care. It could make the condition worse.
- Brain disorders (eg the hardening of brain arteries, alteration in the brain’s structure)
- Kidney disease
- Organ transplant (eg kidney, heart or lung)
- Tendon disorders (eg Rheumatoid Arthritis, etc.) and history of cautiousness. The drug can cause side effects that be worsened.
- Kidney disease – Use with cautiousness. The effects could be increased due to the slower elimination of the medication in the body. Utilizing ciprofloxacin in extended-release tablets of 1000 mg is not recommended for those suffering from severe kidney illness.
- Myasthenia Gravis (severe muscular weakness)–Should not be prescribed to those suffering from this condition.
Properly utilizing Ciprofloxacin
Do not take ciprofloxacin unless recommended by your doctor. Don’t take more of it, don’t take it more frequently and do not use it for a longer period than what your doctor prescribed.
Ciprofloxacin comes with a Medication Guide. Follow the directions carefully. Talk to your doctor if have any concerns.
Ciprofloxacin is most effective with a consistent quantity in urine or blood. To ensure that the amount is steady, don’t take a dose that you are not sure of. It is also recommended to take your doses evenly both at night and day. If, for instance, you plan to take a single daily dose, make sure to do each day at the same moment every day.
If you are required to use the drug ciprofloxacin to treat anthrax infections Your doctor will recommend that you start using it immediately you can after being exposed to anthrax.
It is possible to take Cipro(r) tablets whole. Cipro(r) tablet whole or cut it in half near an angle at the line of scoring. Do not chew or crush it. Inform your doctor if encounter difficulty taking this tablet.
Take this extended-release tablet in its entirety. Don’t crush, break or chew it.
Make sure to shake your mouth liquid for at least 15 seconds before every use. The oral liquid contains tiny microcapsules that are floating in it. They may appear like tiny beads or bubbles. Do not chew on the microcapsules before taking your oral fluid. Take a measurement of the oral liquid using the spoon with the markings included in the bottle.
It is safe to take ciprofloxacin both on its own or with food. It is important to note that Proquin(r) Tablets XR must be taken conjunction in conjunction with a meal at least in the evening, and preferably before dinner.
Take plenty of fluids when you’re taking the drug ciprofloxacin. Drinking more fluids can aid in preventing some undesirable adverse effects of ciprofloxacin.
Take care to avoid taking Ciprofloxacin in isolation in conjunction with yogurt, milk, or any other dairy product. Avoid drinking any juice that contains calcium while taking ciprofloxacin. It is safe to consume dairy products or juices as part of a bigger meal when taking the drug ciprofloxacin.
If you’re taking magnesium-containing or aluminium-containing antacids such as iron supplements, multivitamins, and Lanthanum carbonate other products containing zinc or calcium, do not use them simultaneously with the fact you are taking ciprofloxacin. It is advised to take these drugs at least two hours prior or for 4 to 6 hours after taking the ciprofloxacin. These medications can hinder the ciprofloxacin drug from working effectively.
Continue to take ciprofloxacin throughout the duration of the treatment even if you are feeling better after the first couple of doses. The infection could not heal in the event that you stop using the medication too soon.
The dosage of ciprofloxacin may be different for different people. Follow the instructions of your physician or the instructions in the prescription. The information below is only the typical doses of ciprofloxacin. If your dose differs don’t alter it unless your doctor advises you to change it.
The quantity of medicine you consume is contingent on your strength drug. In addition, the number of doses you will take every day, the interval between doses and the amount of time you use the medication are dependent on the medical condition that you’re treating with the medication.
- For oral dosage forms (extended-release tablets):
- For acute pyelonephritis uncomplicated:
- Adults – 1000 milligrams (mg) daily.
- Children–Use and dosage should be decided upon by your physician.
- In the case of complicated urinary tract infections:
- Adults – 1000 milligrams (mg) daily.
- Children–Use and dosage must be assessed by your physician.
- In the case of uncomplicated urinary tract infections (acute cystitis):
- Adults – 500 milligrams (mg) daily for three days.
- Children–Use and dosage must be determined by your physician.
- For acute pyelonephritis uncomplicated:
- To take oral dosages (suspension and tablets):
- To treat anthrax infections (post-exposure):
- Adults: 500 milligrams (mg) twice a day, each day for at least 60 hours.
- Children–Dose is determined by body weight and should be established by your physician. The usual dose is 15 milligrams (mg) for every kg (kg) that you weigh each day over a period of 60 days. The dose, however, is typically not greater than 500 mg daily.
- For the following symptoms of gonorrhea:
- Adults: 250 milligrams (mg) taken in one dose.
- Children–Use and dosage should be found out by your physician.
- Other infections may be a cause:
- Adults: 250 to 750 milligrams (mg) two times per day, taking it at least every twelve hours.
- Children–Use and dosage should be evaluated by your physician.
- For the purpose of preventing plague:
- Adults: 500 to 750 milligrams (mg) two times per day, each day for 1 hour, over 14 consecutive days.
- Children–Dose based on the weight of your body and is established by your physician. The usual dose is 15 milligrams (mg) each kg (kg) in body mass every 8-12 minutes for 14 consecutive days. But, the dosage usually is not greater than 500 mg daily.
- Urinary tract infections, or severe kidney infections:
- Adults – 250-500 milligrams (mg) twice a day, taking it at least every hour for 7-14 days.
- Children–Dose is determined by body weight and should be determined by your physician. The dosage is typically between 10 and 20 milligrams (mg) per kilogram (kg) of body weight every 12 hours for between 10 and 21 days. But, the dosage is typically not greater than 750 mg daily.
- To treat anthrax infections (post-exposure):
If you do not take a dose of ciprofloxacin do it as quickly as you are able. But, if it’s close to the time for the next dose, you can skip your missed dosage and proceed to your normal dosing schedule. Don’t double doses.
If you have missed a dose of the tablet or liquid and it’s six hours or more before your next dose, you should take any missed doses as fast as you can. Then return to your normal schedule. If you do not take the dose but it’s less than six hours between your next dose then skip the missed dose and then take each dose according to your regular time.
If you don’t take a dose from the extended-release tablets and you have eight hours or more before your next dose, make sure you take your missed dose as quickly as you can. Then resume your regular schedule. If you do not take a dose, and it’s under 8 hours between your next dose then skip the missed dose and then take each dose according to the normal time.
Keep away from the reach of children.
Avoid keeping outdated medicines or medicines that are no longer required.
Discuss with your doctor what you can do with any medication you don’t make use of.
Place the medication in a sealed bottle at room temperatures, and away from moisture, heat and bright light. Be sure to keep the medicine from the medicine from freezing.
It is possible to keep your oral liquid at temperatures at room temp or inside the refrigerator. Don’t put the bottle in a freezer. Do not store your mixture of liquids for longer than fourteen days. Get rid of any remaining liquid within 14 days.
Use caution when using ciprofloxacin.
It is crucial to have your doctor examine the progress of your child or yourself as you take ciprofloxacin. This will enable your doctor to assess whether the medicine is functioning well and decide whether you should continue to make use of it. Urine and blood tests could be necessary to look for undesirable adverse effects.
If your child’s symptoms don’t improve in a couple of days or if they start to get more severe, consult your physician.
Do not take ciprofloxacin if you also take the drug tizanidine (Zanaflex(r)). Inform your doctor whether the child or you also taking theophylline or any other products which contain caffeine (eg coffee, soda chocolate). Utilizing these medicines in conjunction could increase the risk of more severe adverse effects.
Ciprofloxacin is not uncommon to trigger inflammation (tendinitis) or tears of the tendon (the cord that connects muscles and bones). It could happen when you take the medication or when the medication has been stopped. The chance of developing tendon issues is increased when you are older than 60 years old or are taking steroid medications (eg dexamethasone and prednisolone, prednisone Medrol(r)) and suffer from kidney issues that are severe or have a history of recurring tendon issues (eg rheumatoid joint) or have had any organ donation (eg kidney, heart or lung). Consult your physician when you notice an acute pain or swelling of the tendon following exercise (eg in the ankle region, behind of leg or knee or elbow, shoulder, or wrist) and bruising more frequently following an injury or are unable to carry weight or even move your affected region. Avoid exercising until you are told by your doctor otherwise.
Inform your doctor immediately If you are feeling stressed or confused or if you are hearing, seeing or feeling sensations that aren’t present, seizures, excessive headaches, sleep problems or experiencing strange thoughts or behaviour. These could be indications of serious mental issues.
Ciprofloxacin could cause serious allergic reactions, such as anaphylaxis. This could be life-threatening and requires urgent medical treatment. Contact your physician immediately when either you or your children suffer from an itchy, rash hives, or hoarseness. difficulty swallowing or swallowing, or any swelling on your face, hands mouth or throat after taking the ciprofloxacin.
The risk of serious side effects is high in the course of treatment with ciprofloxacin. These side effects sometimes, they are present without prior warning. The warning signs are the following: black, tarry stool and blistering, peeling or loosening of the skin clear or bloody urine, chills, reduced urination, diarrhoea and swelling of the joints or muscles, discomfort or red skin lesions usually with purple-coloured centre ulcers, sores or white spots that appear in your mouth, or around the lips extreme stomach pain, skin inflammation of the fingers, face, feet or lower legs, uncommon bleeding or bruises, an unusual weight increase or yellowing of the eyes or skin. Talk to your doctor immediately If either you or your kid is noticing one of the warning symptoms.
Consult your physician right now if you experience dark urine, dark stools, clay-coloured stool stomach pains, skin or eyes that are yellow. These could be signs of a liver condition that is serious.
Ciprofloxacin can reduce the number of certain types of blood cells that are present in your body. This means that you might bleed or contract infections more frequently. To prevent these issues Avoid being around those with illnesses or who suffer from infections. Make sure to wash your hands regularly. Beware of rough sports and other situations in which you may be smashed or cut. Cleanse or floss your teeth with care. Be cautious when you use sharp objects, like razors and nail clippers.
Ciprofloxacin may cause diarrhoea and in some instances, it may be very severe. It could happen for two months or more following the time your child or you stop taking the drug ciprofloxacin. Do not take any medication to treat diarrhoea without talking to your doctor. Diarrhea medications can make diarrhoea worse or cause it to persist for longer. If you have any concerns about this, or if mild diarrhoea persists or gets worse, consult your physician.
Consult your physician right immediately if you or your child begin experiencing the sensation of tingling, numbness, or burning pains in your arms, hands or legs. This could be a sign of a condition known as peripheral neuropathy.
Ciprofloxacin could increase your chance of having an aneurysm in your aortic (bulge within an artery’s wall most important artery). Talk to your doctor immediately if you experience sudden stomach, chest, and backache, or trouble breathing, coughing or hoarseness.
People who are taking ciprofloxacin might be more sensitive to sunlight than typically. Being exposed to the sun, even at short intervals could result in intense sunburn, skin rashes, and redness, itching or discoloration. If you start using ciprofloxacin:
- Avoid direct sunlight, particularly between 10:00 AM and 3:00 pm If you can.
- Protect yourself by wearing protective clothing, such as sunglasses and a hat.
- Apply a sun blocker with the sun protection factor (SPF) that is at fifteen or more. Certain people might require the use of a product with a higher number of SPF particularly when they have a fair complexion. If you have questions regarding this, talk to your physician.
- Don’t use the sun lamp, tanning booth or.
If you’re experiencing a severe reaction to sun exposure take a look at your doctor.
Ciprofloxacin can cause certain people to feel lightheaded, dizzy, sleepy, or less alert than normal. Don’t drive or engage in any activity that may be risky until you understand the effects of ciprofloxacin on you. If the reactions you experience are particularly painful, consult your physician.
If you’re diabetic and taking diabetes medication orally: Ciprofloxacin may cause hypoglycemia (low blood sugar) in certain patients. Signs that indicate low blood sugar need to be treated prior to leading to involuntary unconsciousness (passing off). There are many different people who experience signs that indicate lower blood sugar. If you notice the symptoms associated with low blood sugar levels, talk to your doctor immediately.
- The signs that indicate low blood sugar be anxiety, behaviours that are similar to those of drunk blurred vision, cold sweats disorientation, pale, cool skin, difficulty concentration, drowsiness, extreme hunger nausea, headache anxiousness, rapid heartbeats shakes, abnormal weakness or fatigue.
Do not take any other medications without discussing them with your physician. This includes prescription and prescription (over-the-counter OTC) medicine, herbal and vitamin supplements.
Ciprofloxacin side effects
In addition to its beneficial effects, medicines can produce unwanted side adverse effects. While not all of these adverse effects can be present, if they do occur, they could require medical attention.
Consult your physician immediately If any of these negative side effects occur:
- Black or bloody or black stool with tarry stools
- burning or crawling the sensation of being numb, or prickly, “pins and needles” or tingling sensations
- Changes in the color of skin
- Changes in the way you urinate
- chest tightness, pain, or discomfort or weight
- Instability or clumsiness
- continuous buzzing or ringing, or any other unidentified sound within the ears
- The act of coughing or spitting blood
- fainting, dizziness, or lightheadedness when rising quickly from a sitting or lying or seated
- rapid and irregular, pounding or racing heartbeats or pulse
- The fever
- Headache, severe and throbbing
- hearing loss
- itchy skin rash
- Joint stiffness
- massive, hive-like swelling that covers the eyelids, face mouth, lips throat, hands, feet, legs, or the genitals
- Light-colored stools
- Muscle pain or stiffness
- Numbness in the hands
- Joint pain
- discomfort or pain in the jaw, arm back, neck, or arms
- red lumps that hurt beneath the skin, mainly on the legs
- The eardrums are pounding
- Swelling or puffiness on the eyelids, around the eyelids, face, lips or tongue
- facial redness and neck and sometimes, the chest.
- extreme stomach cramps, stomach pain, or burning
- shakes in the arms, legs, hands, or feet
- swelling of the feet, face, or lower legs
- swelling, pain lymph glands that are located in the armpit, neck, or the groin
- Vaginal discharge is white, thick, and thick without odor or the slightest odor
- Unsteadiness, trembling, or other coordination or muscle control
- Strange drowsiness, dullness fatigue, weakness, or a sense of slowness
- white spots in the oral cavity or around the tongue
- Skin or eyes with yellow eyes
- Peeling, bludgeoning or loosening of the skin
- Blue-colored lips, fingernails or even palms
- bone discomfort
- diarrhoea, which is watery and severe and can be bloody
- difficulties chewing or breathing or speaking
- double vision
- excess muscular tone
- sensation of discomfort
- sensing or seeing or hearing things that aren’t being felt, seen, or heard that are not
- Increased sensitivity of the skin to the sun
- greater sensitivity to pain or the touch
- Heart rate irregular or slow
- lost sense of smell
- mood shifts
- Rapid heart rate
- Lesions of the skin that are red, typically with a purple-colored centre
- being able to hear, see or sense things that aren’t present
- the sensation of burning sensations on the skin
- severe sunburn
- ulcers, sores or spots of white on lips or inside the mouth
- Eye movements that are not controlled
- unusual bleeding or unusual bleeding or
- extraordinary excitement, nervousness, or unease
- Vaginal yeast infection
There are some side effects that can occur that usually don’t require medical care. These symptoms may disappear after treatment, as the body adapts to the medication. Additionally, your doctor could be able to inform you of ways to avoid or lessen certain adverse effects. Talk to your physician for any of these adverse effects persist or are uncomfortable or if you have concerns about these:
- Nasal stuffiness or runny
Other adverse side effects that are not mentioned could also be present in certain patients. If you experience any other side effects, you should consult with your doctor.
Always consult your doctor to make sure the information presented on this site is appropriate to your particular situation.
SRC: NLM .