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Generic name: acebutolol
The brand name is: Sectral
Dosage forms: oral capsule (200 mg; 400 mg)

What is the meaning of acebutolol?


Acebutolol is a beta blocker. Beta-blockers affect heart health and circulation (blood flows through veins and arteries).

Acebutolol helps treat hypertension ( high blood pressure) and heart rhythm issues.

Acebutolol is also employed for reasons not mentioned in this guideline.


It is recommended not to take Acebutolol in the event of an extremely serious heart problem like “AV block” (2nd or 3rd degree) or serious cardiac failure or slow heartbeats that caused you to faint.

Cardiac Failure

  • Sympathetic stimulation is a crucial factor to support the circulation of patients suffering from diminished myocardial contractility. Moreover, its suppression by blockade of the b-adrenergic receptor can lead to more severe heart failure.


  • While b-blockers are not recommended in patients with a heart condition that is not obvious Acebutolol is a viable option with caution for patients with a history of heart failure that is treated using digitalis and/or diuretics. Both acebutolol and digitalis affect the AV conduction. If the condition persists, treatment with acebutolol must be stopped.

In Patients Without a History of Cardiac Failure

  • For patients suffering from aortic or mitral valve problems or impaired functioning of the left ventricle, prolonged contraction of the myocardium by B-blocking agents for a long time frame can cause heart failure.


  • When the first signs show failing, patients must be digitalized, or treated with a diuretic, and the response closely monitored. If the cardiac condition persists regardless of adequate digitalization or diuretic therapy, acebutolol should be stopped.

Exacerbation of Ischemic Heart Disease Following Abrupt Withdrawal

  • After abrupt discontinuation of treatment with certain b-blocking medications for patients suffering from coronary artery disease, angina pectoris can be aggravated. In certain instances, myocardial ischemia and death have been documented. Thus, patients who suffer from this condition are advised to avoid abrupt interruptions of treatment without a physician’s recommendation.


  • In the absence of any obvious heart disease If the discontinuation of acebutolol has been planned patients should be monitored closely and be instructed to limit physical activities to a minimum when the drug is gradually removed over approximately two weeks. (If treatment with an alternative b-blocker is needed then the patient can be shifted directly to similar doses of a different agent, without interruption to b-blocking therapy.)


  • If an increase in angina pectoris happens the antianginal treatment should be immediately restarted at full dosages and the patient should be hospitalized until the condition improves.

Peripheral Vascular Disease

  • Treatment with b-antagonists decreases the cardiac output and may cause or worsen those symptoms associated with arterial insufficiency in patients with mesenteric or peripheral vascular disease. It is important to exercise caution when treating those with these conditions, and they must be watched closely for signs of the increase in arterial obstruction.

Bronchospastic Disease

  • Patients with BRONCHOSPASTIC DISEASE should, in general not receive a BLOCKER B-type. Due to its selective b1-selectivity however, small doses of acebutolol can be administered with caution to patients suffering from bronchospastic diseases who are not responding to, or cannot accept, other treatment options.


  • Because b1-selectivity does not exist in absolute terms and is dependent on dose it is recommended that the lowest dose of acebutolol must be administered initially, and usually in doses divided to avoid higher plasma levels that can be associated with a longer duration of the dose-interval. A bronchodilator such as theophylline or a b2-stimulant must be available before time with the instructions for the use of it.

 Major Surgery

  • The treatment of beta-blocking that is regularly administered is not recommended to be stopped prior to major surgery. However, the decreased heart’s ability to respond to the reflex adrenergic stimuli can increase the risk of general anesthesia as well as surgery.

Diabetes and Hypoglycemia

  • B-blockers could increase the severity of insulin-induced hypoglycemia and may mask certain manifestations, including tachycardia. however, sweating and dizziness are not usually affected in any way. Patients with diabetes should be aware of the possibility of masked hypoglycemia.


  • The B-adrenergic blockade could mask symptoms (tachycardia) that indicate hyperthyroidism. A sudden withdrawal of b-blockade can trigger a thyroid storm. consequently, those who are suspected of developing thyrotoxicosis and from who acebutolol is to be discontinued must be observed closely.

Before you start taking this medicine, make sure to consult your doctor

It is not recommended to take acebutolol in the event that you are allergic to it or you suffer from serious heart disease, for example:

  • Block AV (2nd and 3rd degrees);
  • severe heart failure; or
  • low heartbeats can cause you to faint.

To ensure that acebutolol’s appropriate for you, inform your physician if you are suffering from:

  • coronary arterial disorder (hardened coronary arteries);
  • peripheral vascular disease, such the Raynaud’s disease;
  • A previous history of heart failure
  • an underlying heart condition that you have prescribed digoxin (digitalis) or diuretics (“water tablet”);
  • asthma, chronic obstructive lung disorder ( COPD), sleep apnea or other breathing disorders;
  • diabetes (taking Acebutolol could make it more difficult to recognize when you’ve got the condition of having low glucose);
  • kidney or liver disease;
  • A thyroid disorder
  • A background that is a result of an allergy history.

Adults who are older may be more vulnerable to the effects of Acebutolol.

It isn’t known if this medication will cause harm to the unborn baby. However, taking acebutolol in pregnancy can cause issues when the baby is born. This can include the baby’s weight being low, slow heartbeats and lower blood pressure. Inform your doctor if are expecting or planning to be pregnant while taking Acebutolol.

Acebutolol may be absorbed in breast milk and could harm a nursing child. Do not breastfeed during the course of taking this medication.

How to take this Acebutolol?

Follow all the instructions on the prescription label. Your doctor could change the dose of your medication to ensure that you receive the most effective outcomes. Don’t take this medication in greater or lesser quantities or for longer periods than prescribed.

If you are undergoing surgery, inform your surgeon in advance that you’re using Acebutolol. You might have to stop taking the medication for a brief period of time.

Your blood pressure is likely to be checked regularly.

It is important not to stop taking Acebutolol abruptly. The sudden stop could cause your condition to get worse.

If you’re being treated with high blood pressure you should continue taking this medication even if you feel good. High blood pressure can have no signs. It could be necessary to take medication for blood pressure throughout your life.

Acebutolol is just one component of a full treatment plan which could also comprise exercise, diet, and weight loss. Follow the instructions of your physician precisely.

Maintain at room temperature far from heat, moisture and light.

Make sure the bottle is tightly shut when not in use.

If I don’t take a dose?

You should take the missed dose as quickly as you can remember. Avoid your missed dosage if it’s close to the time of the next dose. Don’t take any extra medication to make up for the missed dose.

How do I react if consume too much?

Get medical attention immediately or contact for help at the Poison Help line at 1-800-222-1222.

Overdose symptoms can include slow heartbeats and breathing problems or breathing, extreme disorientation, the feeling of fainting or seizures (convulsions).

What to avoid while taking Acebutolol?

Consuming alcohol with acebutolol could result in adverse effects.

Talk to your doctor or pharmacist prior to taking any cold or cough medicine that contains decongestants. Combining acebutolol with a decongestant can increase blood pressure to potentially dangerous levels.

The medicine could affect your ability to think or react. Be cautious when you drive or perform any activity that requires you to be alert.

Acebutolol side effects

Contact a medical professional immediately Get medical attention immediately if you notice symptoms warning signs of an allergic reaction, such as an allergic reaction that causes hives and breathing problems or swelling of your lips, face and tongue.

Contact your doctor immediately If you suffer from:

  • Shortness of breath (even when exerting only a little) swelling rapidly gaining weight;
  • New or worsening chest pain that isn’t getting better or worse;
  • Heartbeats that are slow;
  • a euphoric feeling, similar to you’re about to pass out or
  • extremely high blood pressure – severe headache blurred vision the feeling of pounding in your neck and the ears, nosebleeds anxiety and confusion, severe chest discomfort, breathlessness abnormal heartbeats.

Common side effects can be:

This isn’t a complete list of all side effects. others could happen. Contact your physician for advice regarding medical adverse effects. You can report symptoms to FDA at 1-800-FDA-1088.

Acebutolol dosing information

Usual Adult Dose for Hypertension:

Initial dosage: 400 mg orally daily in 1 to 2 equal doses
Dosage for maintenance: 400- 800 mg taken orally daily

Comment: Some patients could react to just 200 mg taken orally daily Patients who are not adequately managed hypertension or with more severe symptoms could respond to 600 mg taken orally daily or the addition of another antihypertensive. Beta-1 selectiveness decreases as the dose increases.

Usual Adult Dose for Ventricular Arrhythmia:

Initial dosage: 200 mg orally every day, twice
Maintenance dose: 600 – 1200 mg taken orally daily

What other drugs can impact acebutolol?

Discuss with your physician all the medicines you are currently taking and any that you begin or stop taking, particularly:

  • reserpine;
  • cold medicine, stimulant medications and diet tablets;
  • These are NSAIDs (nonsteroidal anti-inflammatory drugs)–aspirin Ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve) and celecoxib diclofenac, indomethacin and meloxicam and others;
  • other beta-blockers–atenolol, carvedilol, metoprolol, nebivolol, propranolol, sotalol, and others.

This list isn’t complete. Other medications can interfere with acebutolol. These include prescription and over-the-counter medicines, vitamins, and herbal products. The interactions of all potential interactions are included in this guideline for medication.

More details

Keep all medicines away from the reach of children. Do not give your medication to anyone else and use this medicine only in the prescribed indication.

Always consult your physician to confirm that the information provided on this site is appropriate to your particular situation.

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