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Name of the generic: Tirofiban (Intravenous way)

Drug class: Glycoprotein inhibitors of platelets


Brand name in the USA

  • Aggrastat

Available Dosage Forms:

  • Solution

Therapeutic Class: Platelet Aggregation Inhibitor

Pharmacologic Class: Glycoprotein IIb/IIIa Inhibitor

Uses for Aggrastat

Tirofiban injections keep blood clots away from forming within the arteries of the heart in the event of certain kinds of chest pain or heart attacks. It can also be administered in patients who undergo specific blood vessel and heart procedures.

Tirofiban can be described as an antiplatelet medication. It lowers the risk that a clot with a bad reputation will develop by stopping certain cells in blood from colliding.

This medication should be administered only by or under the supervision of your physician.

Before using Aggrastat

When deciding whether to take any medicine, the dangers of taking the medicine have to be evaluated against the benefits it will bring. This is a decision that you and your physician will take. In this case to be considered, the following factors should be taken into consideration:


Discuss with your physician whether you’ve had any allergic or unusual reaction to this medication or any other medication. Inform your health care doctor if you are suffering from other allergies, for example, to dyes, foods or preservatives or animals. For products that are not prescription-only, you must review the label or the the ingredients on the package carefully.


Studies have not been conducted on the relation of age to the effect of the tirofiban injection in the children’s population. Safety and effectiveness haven’t been established.


Studies that are appropriate up to now haven’t revealed specific geriatric issues that could restrict the use of the injection of tirofiban in the older.



There aren’t enough studies of women that can determine the risks to babies when taking this medication while breastfeeding. Be sure to weigh the benefits of this medication against the risk of using this medication during nursing.

Interactions with medications

Certain medicines shouldn’t be combined in any way however, there are instances where two medicines can be combined even though there is a chance of interaction. In these situations the doctor may decide to adjust the dose or take other precautions if needed. If you’re taking this medication, it is crucial that you let your doctor know that there is a connection between any one of these medications that are listed below. These interactions have been determined based on their potential impact and may not be all-inclusive.

The use of this medication in conjunction with any of these medications is not recommended. Your doctor could choose not to treat you with this medicine or modify any other medication you are taking.

Utilizing this medicine in conjunction together with any of the following medications is generally not recommended, but it could be necessary in certain situations. If two medicines are prescribed in conjunction the doctor could alter the dosage or the frequency you use either of the drugs.

  • Aceclofenac
  • Acemetacin
  • Alipogene Tiparvovec
  • Alteplase, Recombinant
  • Amtolmetin Guacil
  • Anagrelide
  • Apixaban
  • Ardeparin
  • Argatroban
  • Aspirin
  • Bemiparin
  • Betrixaban
  • Bivalirudin
  • Bromfenac
  • Bufexamac
  • Caplacizumab-yhdp
  • Celecoxib
  • Certoparin
  • Choline Salicylate
  • Cilostazol
  • Citalopram
  • Clonixin
  • Dabigatran Etexilate
  • Dalteparin
  • Danaparoid
  • Desirudin
  • Desvenlafaxine
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dipyridamole
  • Dipyrone
  • Droxicam
  • Duloxetine
  • Edoxaban
  • Enoxaparin
  • Escitalopram
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Fluoxetine
  • Flurbiprofen
  • Fluvoxamine
  • Fondaparinux
  • Heparin
  • Ibrutinib
  • Ibuprofen
  • Indomethacin
  • Inotersen
  • Ketoprofen
  • Ketorolac
  • Lepirudin
  • Levomilnacipran
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Milnacipran
  • Morniflumate
  • Nabumetone
  • Nadroparin
  • Naproxen
  • Nefazodone
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Parnaparin
  • Paroxetine
  • Phenindione
  • Phenprocoumon
  • Phenylbutazone
  • Piketoprofen
  • Piracetam
  • Piroxicam
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Protein C
  • Reviparin
  • Rivaroxaban
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Selumetinib
  • Sertraline
  • Sodium Salicylate
  • Sulindac
  • Tenoxicam
  • Tiaprofenic Acid
  • Ticagrelor
  • Tinzaparin
  • Tolfenamic Acid
  • Tolmetin
  • Trazodone
  • Valdecoxib
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • Warfarin

Utilizing this medicine in conjunction in conjunction with one of the following drugs could cause an increased risk of some adverse reactions, but taking both medications could be the best option for you. If you are prescribed both medications by your doctor, they might alter the dosage or frequency at which you take one or both drugs.

  • Vitamin A

Interactions with alcohol, tobacco, or food

Certain medications shouldn’t be taken during or near the time of taking food, or eating specific kinds of food as interactions could happen. Smoking or drinking alcohol in conjunction along with certain medications may result in interactions. The below interactions were selected in light of their potential importance and may not be all-inclusive.

Other medical conditions

The presence of any other medical conditions could affect the effectiveness of this medication. Be sure to inform your physician if you suffer from any other medical issues including:

  • Active bleeding or
  • Bleeding issues (eg bleeding diathesis) and the history of or
  • Major operation (within the last thirty days) or
  • Injury that is severe (within the last thirty days) or
  • Thymbocytopenia (low platelets in blood) It is a history that should not be used for patients with these conditions.
  • Kidney disease – Use with care. The effect may be heightened because of the slower removal of the medication out of the body.

Proper use of Aggrastat

A physician or other qualified health professional will prescribe the medicine. The medicine is given via the injection of a needle in one of your veins. Most commonly this medicine is used for acute coronary syndrome (ACS)

You will receive a continuous dose of this medicine for the course of 18 hours. During this time, are closely monitored to ensure the medicine is effective and not causing undesirable negative side negative effects.

Safety precautions when using Aggrastat

It is vital to have your doctor examine you on a regular basis following your departure from the hospital to check for any issues which could be caused by this medication. Urine and blood tests are needed to look for adverse negative effects. Make sure you keep all appointments.

There is a chance that you will bruise or bleed more frequently while taking this medicine. Take extra care to avoid injury until you feel the effect of medication have subsided.

Talk to your doctor immediately if you observe an unusual bruise or bleeding, dark blue stools, blood in your urine or stools or the appearance of red spots on your face. Avoid picking your nose. If you must air your nostrils, do so gently. it slowly.

It is possible to be instructed to use a soft brush or to shave using the aid of an electric razor (not an actual razor) for some days following you’ve been prescribed the medication. This reduces the chance of bleeding.

Check for bleeding in open areas , such as the locations of needle punctures for taking blood, administering shots, or inserting the catheter to perform a coronary catheterization, or an angioplasty. Also, look for the presence of blood within your urine, or the bowel movements. If you experience injuries or bleeding, inform your doctor as soon as possible.

Do not take any other medications without discussing them with your physician. This includes prescription and prescription (over-the-counter OTC) medicine, herbal and vitamin supplements.

Aggrastat side effects

In addition to its beneficial effects, some medicines may produce unwanted side adverse effects. Although not all negative side effects are likely to occur, if they occur, they could require medical attention.

Talk to your doctor or nurse right away when any of these adverse effects happen:


More popular

  • Pain in the stomach or abdomen or swelling
  • back, arm or jaw discomfort in the back, arm, or jaw
  • Black, tarry stool
  • Eyes are a source of blood.
  • Blood in the urine
  • bruises or areas of purple on the skin
  • chest discomfort or pain
  • chest tightness, or heaviness
  • It is coughing up blood.
  • reduced alertness
  • rapid or irregular heartbeat
  • headache
  • joint swelling or pain
  • nausea
  • nosebleeds

Less well-known

  • Bleeding gums
  • fainting or lightheadedness
  • Red spots that are specific on the skin
  • excessive, unusual fatigue or fatigue
  • slow heartbeat
  • swelling of feet, ankles, hands or lower leg swelling

The exact cause is not known.

  • Fever or chills
  • cough
  • difficulties in swallowing
  • Swelling or puffiness on the eyelids and around the eyelids, face, lips or tongue
  • the skin, hives or itching
  • Trouble breathing

Certain side effects can be experienced but they usually do not require medical care. These side effects can disappear after treatment, as your body adjusts your. Additionally your doctor could be able inform you how to avoid or minimize the effects of these adverse effects. Talk to your physician for any of these symptoms persist or become uncomfortable or if you have concerns about these:

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  • The legs are aching or hips

Less popular

Other adverse side effects that are not listed could also be present in certain patients. If you observe any other symptoms, consult with your physician.

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