Rebinyn Dosage

 Recommended Adult Dosing

Dosage forms:  INJ

Hemophilia B

[bleeding episode, minor-moderate]

Dose: 40 units/kg/dose IV x1; may repeat dose (interval not defined) until hemostasis; Info: dose, duration varies by site/severity of bleeding, severity of deficiency, and presence of inhibitors

[bleeding episode, major]

Dose: 80 units/kg/dose IV x1; may give additional 40 units/kg/dose IV (interval not defined) until hemostasis; Info: dose, duration varies by site/severity of bleeding, severity of deficiency, and presence of inhibitors

[bleeding prophylaxis, minor surgery]

Dose: 40 units/kg/dose IV x1 preop; may repeat dose (interval not defined) until hemostasis; Info: dose, duration varies by site/severity of bleeding, severity of deficiency, and presence of inhibitors

[bleeding prophylaxis, major surgery]

Dose: 80 units/kg/dose IV x1 preop; may give additional 40 units/kg/dose IV q1-3 days x1wk, then qwk until hemostasis; Info: dose, duration varies by site/severity of bleeding, severity of deficiency, and presence of inhibitors

[bleeding prophylaxis, routine]

Dose: 40 units/kg/dose IV qwk; Info: adjust dose based on clinical response

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]