Lisinopril
Generic name Lisinopril
Name of the brand: Prinivil, Qbrelis, Zestril
Dosage formats: oral solution (1 mg/mL) Oral tablet (10 mg; 2.5 mg; 20 mg 30 mg 5 mg; 40 mg)
The class of drug: Angiotensin Converting Enzyme Inhibitors
What is Lisinopril?
Lisinopril can be described as an ACE inhibitor. ACE stands for angiotensin converting enzyme.
Lisinopril can be used for treating high blood pressure (hypertension) in adults as well as children who are at or above the age of 6 years.
Lisinopril can also be used to treat adult congestive heart failure and to prolong the life of patients following the event of a heart attack.¶
Warnings
Lisinopril should not be used in the event that you are expecting. It could harm the unborn baby. Stop taking this medication and inform your doctor right when you begin to become pregnant.
This medication if you’ve ever experienced angioedema. Don’t take lisinopril in the 36 hours prior to or after using a medicine that includes sacubitril (such as Entresto).
If you are diabetic take care not to use the medication lisinopril that has an aliskiren (such as Amturnide, Tekturna, Tekamlo).
It is also possible to avoid taking lisinopril in conjunction with aliskiren in the event of renal disease.
Before you start taking this medicine, make sure to consult your doctor.
Lisinopril should not be used in the event that you have an allergy to the drug, or:
- are afflicted with angioedema
- Recently, I was prescribed a heart drug called sacubitril.
- Are intolerant to another ACE inhibitor, including benazepril and captopril. They also react to enal fosinopril, moexipril perindopril or trandolapril.
Take lisinopril for a period of 36 hours of taking a medicine that contains sacubitril (such as Entresto).
If you suffer from diabetic issues, don’t take Lisinopril in conjunction with any other medication that has an aliskiren (such as Tekturna and Tekamlo).
It is also possible to stay clear of taking lisinopril along with aliskiren when you suffer from kidney problems.
To ensure this medicine is suitable for you, inform your physician if you’ve previously had:
- Kidney disease (or if you’re on dialysis);
- liver disease
- Potassium levels are high within your blood.
Don’t take lisinopril when you are expecting. If you are pregnant then stop taking this medication and inform your doctor promptly. This medication can cause harm or even death for the unborn baby if use it in the third or second trimester. Make sure you use effective birth control when taking this medication.
It isn’t known if Lisinopril can be absorbed into breast milk or whether it can harm babies who are nursing. Do not breastfeed when taking this medication.
What should I do to use Lisinopril?
Lisinopril should be taken exactly as directed by your physician. Follow the directions on the label of your prescription. Your doctor could change your dosage to ensure that you receive the most effective outcomes. Don’t take this medication in greater or lesser doses or for longer periods than the recommended time.
Drink plenty of water during the course of taking this medication.
Lisinopril is a medicine that can be taken either with or without meals.
Take measurements of liquid medicines using the dosing syringe that comes with it, or using a specially-designed dosing spoon or medicine cups. If you do not own an instrument for measuring doses request one from your pharmacist. one.
Your blood pressure is likely to be monitored frequently. Electrolytes and kidney function could also be examined.
Contact your physician if you are suffering from persistent diarrhea or vomiting or if you’re sweating more than normal. It is possible to become dehydrated when taking this medication. This can result in lower blood pressure and electrolyte imbalances or kidney failure when you take Lisinopril.
If you require surgery, inform your surgeon beforehand that you’re taking Lisinopril.
If you suffer from hypertension, continue the medication, even if you feel good. High blood pressure can have no signs. You could need medication to lower your blood pressure throughout your life.
Storage at room temperature far from heat and moisture. Don’t freeze or store the liquid in your mouth.
Dosing information
Usual Adult Dose for Hypertension:
Initial dosage: 10 mg orally every day 5 mg orally, at least once per day.
The dose for maintenance is 20-40 mg once orally every day
The maximum dosage is 80 mg taken orally, every day, once
Comments:
The dose starts at 5 mg taken orally, once a day for patients taking diuretics.
The 80 mg dose is recommended, however, it doesn’t appear to provide more effect.
If blood pressure cannot be controlled by lisinopril it is recommended that a small dose of a diuretic could be added (e.g. hydrochlorothiazide 12.5 mg). Following the addition of diuretics, it could be possible to decrease the dosage of lisinopril.
Usual Adult Dose for Congestive Heart Failure:
Initial dosage: 2.5 to 5 mg daily, orally
Dosage of maintenance dose: Dosage can be gradually increased until it is tolerated.
Maximum dosage 40 mg, orally at least once per day
Comments:
The diuretic dose could need to be adjusted in order to lessen hypovolemia that could cause hypotension. Hypotension that is evident after the first dose of Lisinopril is not a reason to stop subsequent dosage titration using the drug.
Usual Adult Dose for Myocardial Infarction:
Initial dosage 5 mg taken in a single dose (within 24 hours after the beginning of the acute myocardial infarction)
The next dose is 5 mg orally after 24 hours, followed by 10 mg orally following 48 hours.
Dosage for maintenance is 10 mg taken orally, daily. The dosage should be maintained for six weeks at the earliest.
Comments:
Therapy should begin at 2.5 mg for patients suffering from systolic blood pressure that is low (less than or equivalent to 120mmHg or higher than 100 millimeters) within the first three days following the infarct. If hypotension persists for a long time (systolic blood pressure lower than 90 mmHg over 1 hour) therapy should be discontinued.
Usual Adult Dose for Diabetic Nephropathy:
Initial dosage: 10-20 mg once orally every day
Dose for maintenance of 20-40 mg once orally every day
Dosage can be adjusted upward each 3 days
Comments:
Not an official indication.
Usual Geriatric Dose for Hypertension:
Initial dosage: 2.5 to 5 mg daily, orally
Dosages for maintenance are recommended to be increased from 2.5 mg to five mg daily in 1 to 2-week intervals.
The maximum dosage is 40 mg taken orally, at least once per day
Usual Pediatric Dose for Hypertension:
Children who are older than or equivalent to 6 years age:
The initial dose is 0.07 mg/kg, orally twice every day (Maximum dosage is 5 mg once per day)
Dosage for maintenance should be adjusted in accordance with blood pressure responses between 1 and 2 weeks intervals.
Max doses: The dosage greater than 0.61 mg/kg or higher than 40 mg haven’t been examined in pediatric patients
Comments:
It is not recommended for patients in the pediatric age group of fewer than six years old or those who have a glomerular filtration rate lower than 30 mL/min.
Detailed Lisinopril dosage information
How do I deal with it if do not take the dose?
Do the dose missed as soon as you can remember. Avoid your missed dosage if it’s close to the time of the next dose. Don’t take any extra medication to make up for the missed dose.
If I take too much?
For medical emergencies, seek emergency medical attention or contact toll-free the Poison Help line at 1-800-222-1222.
What can you do to be aware of to
Drinking alcohol may increase your blood pressure, and can also cause an increase in certain adverse effects of lisinopril.
Beware of becoming dehydrated or overheated when you exercise, particularly during the heat, or by insufficient fluid intake. Lisinopril reduces sweating and makes you more vulnerable to suffering heatstroke.
Do not take salt substitutes or potassium supplements when you are taking this medication unless your doctor has instructed you to.
Do not get up too quickly from lying or sitting in a position where you could be dizzy. Make sure to get up slowly and steadily yourself to avoid falling.
Lisinopril side effects
Take immediate medical attention If you exhibit symptoms warnings of an allergic reaction to Lisinopril such as hives, extreme stomach pain, trouble breathing, swelling of your lips, face, and tongue. You are more susceptible to the reaction to an allergen if are an African-American.
Contact your doctor immediately If you are suffering from:
- a euphoric feeling, similar to you’re about to pass out.
- Sore throat, fever;
- high potassium levels – nausea, weak and tingling sensations chest pain, irregular heartbeats loss of motion;
- kidney issues – less or no urination on your ankles and feet and feeling exhausted or short of breath,
- liver disorders – nausea abdominal pains, itching fatigue nausea, loss of appetite black stools, dark urine, and jaundice (yellowing of the eyes or skin).
Common side effects of lisinopril are:
- headache, dizziness;
- cough
- chest pain.
This is not a comprehensive list of all side effects. other side effects could occur. Contact your physician for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.
What other medications can have an effect on Lisinopril?
Inform your doctor about the medicines you are currently taking and any that you begin or stop taking, particularly:
- diuretic, also known as “water pill”;
- lithium;
- Gold injections for arthritis;
- oral diabetes medication or insulin;
- a potassium supplement;
- Medicine to prevent rejection of organ transplants: everolimus; sirolimus; tacrolimus, temsirolimus, or
- These are NSAIDs (nonsteroidal anti-inflammatory medicines) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve) Celecoxib, diclofenac, indomethacin and meloxicam, and many others.
This list isn’t complete. Other medications can be incompatible with lisinopril, such as prescription and over-the-counter medicines such as vitamins, herbal products. The interactions of all potential interactions are included in this guideline for medication.