Kyprolis Dosage
Kyprolis Dosage Generic name: carfilzomib Drug class: Proteasome inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Multiple myeloma, relapsed or refractory [monotherapy, 27 mg/m^2 dose] Dose: 20 mg/m^2/dose IV x1 on days 1 and 2, then 27 mg/m^2/dose IV x1 on days 8, 9, 15, 16 of 28-day cycle for cycle 1, then 27 […]
Koselugo Dosage
Koselugo Dosage Generic name: selumetinib Drug class: Multikinase inhibitors Medically reviewed by A Ras MD. Recommended Peds Dosing Dosage forms: CAP: 10 mg, 25 mg Neurofibromatosis, type 1 [2 yo and older, BSA 0.55-0.69 m^2] Dose: 25 mg/m^2/dose PO bid (round to 20 mg PO qam, 10 mg PO qpm); Info: for pts w/ symptomatic, inoperable plexiform […]
Krintafel Dosage
Krintafel Dosage Generic name: tafenoquine Brand names: Arakoda, Krintafel Drug class: Antimalarial quinolines Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 150 mg Malaria prophylaxis, terminal [P. vivax] Dose: 300 mg PO x1; Info: for presumptive antirelapse tx (PART); give on same day as last primary prophylaxis dose of chloroquine and hydroxychloroquine; do not […]
Krystexxa Dosage
Krystexxa Dosage Generic name: pegloticase Drug class: Antihyperuricemic agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Gout, refractory chronic [monotherapy] Dose: 8 mg IV q2wk; Info: start gout flare prophylaxis w/ NSAID or colchicine >1wk before pegloticase initiation and cont. >6mo; D/C oral urate-lowering meds before and during tx; screen pts of […]
Kuvan Dosage
Kuvan Dosage Generic name: sapropterin Drug class: Miscellaneous metabolic agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 100 mg; PWDR: 100 mg per pkt, 500 mg per pkt PKU [5-20 mg/kg/dose PO qd] Start: 10-20 mg/kg/dose PO qd; Max: 20 mg/kg/day; Info: adjust dose based on Phe levels; give w/ food; D/C […]
Kybella Dosage
Kybella Dosage Generic name: deoxycholic acid> Drug class: Miscellaneous uncategorized agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ: 10 mg per mL Restricted Distribution in US Submental fat convexity, mod-severe [2 mg/cm^2 SC per injection] Max: 50 injections per tx up to 6 tx; Info: tx should be at least 1mo apart […]
Kyleena Dosage
Kyleena Dosage Generic name: remdesivir Drug classes: Investigational drugs, Purine nucleosides Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: IUD: 19.5 mg Restricted Distribution in US contraception [1 IUD q5y] Start: w/in 7 days of menses onset, immed. after 1st trimester abortion or miscarriage, immed. postpartum or after 2nd trimester abortion or miscarriage after placenta […]
Kynmobi Dosage
Kynmobi Dosage Generic name: apomorphine hydrochloride Drug class: Dopaminergic antiparkinsonism agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: SL STRIP: 10 mg, 15 mg, 20 mg, 25 mg, 30 mg; convenience pack Acute intermittent hypomobility, Parkinson dz-assoc. [10-30 mg SL prn] Start: 10 mg SL x1 test dose during off episode; […]
Librax Dosage
Librax Dosage Generic name: chlordiazepoxide and clidinium Drug class: Anticholinergics / antispasmodics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 5 mg/2.5 mg IBS, adjunct tx [1-2 caps PO tid-qid] Info: give before meals and at bedtime; taper dose gradually to D/C PUD, adjunct tx [1-2 caps PO tid-qid] Info: give before meals […]
Libtayo Dosage
Libtayo Dosage Generic name: cemiplimab-rwlc Drug class: Anti-PD-1 monoclonal antibodies Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Cutaneous squamous cell CA, locally advanced or metastatic [350 mg IV q3wk] Info: for pts not eligible for curative surgery or XRT Basal cell CA, locally advanced or metastatic [350 mg IV q3wk] Info: […]