Krintafel Dosage

Generic name: tafenoquine
Brand names: Arakoda, Krintafel
Drug class: Antimalarial quinolines

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 150 mg

Malaria prophylaxis, terminal

[P. vivax]
Dose: 300 mg PO x1; Info: for presumptive antirelapse tx (PART); give on same day as last primary prophylaxis dose of chloroquine and hydroxychloroquine; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC Yellow Book
[*P. ovale]
Dose: 300 mg PO x1; Info: for presumptive antirelapse tx (PART); give on same day as last primary prophylaxis dose of chloroquine and hydroxychloroquine; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC Yellow Book

Malaria antirelapse tx

[P. vivax]
Dose: 300 mg PO x1; Info: give on day 1 or day 2 of chloroquine or hydroxychloroquine tx or as soon as possible after tx; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC guidelines
[*P. ovale]
Dose: 300 mg PO x1; Info: give on day 1 or day 2 of chloroquine or hydroxychloroquine tx or as soon as possible after tx; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC guidelines

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  TAB: 150 mg

Malaria prophylaxis, terminal

[P. vivax]
Dose: 300 mg PO x1; Info: for presumptive antirelapse tx (PART) in pts 16 yo and older; give on same day as last primary prophylaxis dose of chloroquine or hydroxychloroquine; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC Yellow Book
[*P. ovale]
Dose: 300 mg PO x1; Info: for presumptive antirelapse tx (PART) in pts 16 yo and older; give on same day as last primary prophylaxis dose of chloroquine or hydroxychloroquine; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC Yellow Book

Malaria antirelapse tx

[P. vivax]
Dose: 300 mg PO x1; Info: for pts 16 yo and older; give on day 1 or day 2 of chloroquine or hydroxychloroquine tx or as soon as possible after tx; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC guidelines
[*P. ovale]
Dose: 300 mg PO x1; Info: for pts 16 yo and older; give on day 1 or day 2 of chloroquine or hydroxychloroquine tx or as soon as possible after tx; do not cut/crush/chew tab; give w/ food; may repeat dose x1 if vomiting occurs w/in 1h; refer to CDC guidelines

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

 

SRC: NLM .