Xpovio Dosage

Xpovio Dosage Generic name: selinexor Drug class: Miscellaneous antineoplastics Medically reviewed by  A Ras MD.    Recommended Adult Dosing Dosage forms:  TAB: 20 mg, 40 mg, 50 mg, 60 mg Special Note [uses, dosing may vary] Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, concomitant meds to mitigate toxicity, and dosing incl. […]

Xtampza ER Dosage

Xtampza ER Dosage Generic name: oxycodone Drug class: Narcotic analgesics Medically reviewed by  A Ras MD.  Recommended Adult Dosing Dosage forms:  ER CAP: 9 mg, 13.5 mg, 18 mg, 27 mg, 36 mg Pain, severe chronic [opioid-naive or opioid-nontolerant pts] Dose: individualize dose PO q12h; Start: 9 mg PO q12h, may incr. total daily dose by […]

Xtandi Dosage

Xtandi Dosage Generic name: enzalutamide Drug classes: Antiandrogens, Hormones / antineoplastics Medically reviewed by  A Ras MD.    Recommended Adult Dosing Dosage forms:  CAP: 40 mg; TAB: 40 mg, 80 mg Prostate CA [castration-resistant dz] Dose: 160 mg PO qd; Info: use w/ GnRH analog in pts w/o bilateral orchiectomy; do not open/dissolve cap; do not cut/crush/chew tab […]

Xultophy Dosage

Xultophy Dosage Generic name: insulin degludec and liraglutide Medically reviewed by  A Ras MD.    Recommended Adult Dosing Dosage forms:  INJ (pen): 100 units/3.6 mg per mL Diabetes mellitus, type 2 [basal insulin or GLP-1 agonist tx-naive pts] Dose: 10-50 units SC qd; Start: D/C basal insulin or GLP-1 agonist, then start insulin degludec/liraglutide 10 units […]

Xuriden Dosage

Xuriden Dosage Generic name: Uridine Triacetate (Xuriden) Drug classes: Antidotes, Miscellaneous metabolic agents Medically reviewed by  A Ras MD.  Recommended Adult Dosing Dosage forms:  GRANULE: 2000 mg per pkt Hereditary orotic aciduria [60-120 mg/kg/dose PO qd] Start: 60 mg/kg/dose PO qd; Max: 8000 mg/day; Info: give w/ soft food; do not crush/chew granules Renal dosing [not defined] renal impairment: […]

Xyntha Dosage

Xyntha Dosage Generic name: antihemophilic factor (recombinant) Drug class: Miscellaneous coagulation modifiers Medically reviewed by  A Ras MD.  Recommended Adult Dosing Dosage forms:  INJ Hemophilia A [bleeding episode, minor] Dose: individualize dose IV x1; may repeat dose q12-24h until hemostasis; Info: estimated dose (units) = [wt (kg) x desired factor VIII level (%) x 0.5] where desired […]

Parnate Dosage

Parnate Dosage Generic name: tranylcypromine sulfate Recommended Adult Dosing Dosage forms:  TAB: 10 mg Depression [10 mg PO tid] Start: 10 mg PO tid x2wk, may incr. by 10 mg/day q1-3wk; Max: 60 mg/day; Info: taper dose gradually to D/C Renal dosing [see below] renal impairment: not defined, caution advised HD/PD: not defined, caution advised Hepatic […]

Lamictal XR Dosage

Lamictal XR Dosage Generic name: lamotrigine Brand names: LaMICtal, LaMICtal ODT, LaMICtal XR, Subvenite Drug class: Triazine anticonvulsants Medically reviewed by  A Ras MD.   Recommended Adult Dosing Dosage forms:  ER TAB: 25 mg, 50 mg, 100 mg, 200 mg, 250 mg, 300 mg; blue convenience pack; green convenience pack; orange convenience pack Partial seizures [conversion to monotherapy] […]

Lampit Dosage

Lampit Dosage Generic name: nifurtimox Drug class: Miscellaneous antibiotics Medically reviewed by  A Ras MD.   Recommended Adult Dosing Dosage forms:  TAB: 30 mg, 120 mg Chagas dz [8-10 mg/kg/day PO divided tid-qid x60-90 days] Info: give w/ food Human African trypanosomiasis [15 mg/kg/day PO divided tid x10 days] Info: for 2nd stage dz caused by Trypanosoma brucei […]

Lanadelumab Dosage

Lanadelumab Dosage Generic name: lanadelumab Brand names: Takhzyro, Takhzyro Pre-filled Syringe Drug class: Hereditary angioedema agents Medically reviewed by  A Ras MD.   Recommended Adult Dosing Dosage forms:  INJ: 150 mg per mL Restricted Distribution in US [1-866-888-0660 or www.takhzyro.com for more info] Special Note [formulation clarification] Info: nonproprietary name = lanadelumab-flyo Hereditary angioedema prophylaxis, routine [300 mg […]