Xtandi Dosage

Generic name: enzalutamide
Drug classes: Antiandrogens, Hormones / antineoplastics

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  CAP: 40 mg; TAB: 40 mg, 80 mg

Prostate CA

[castration-resistant dz]
Dose: 160 mg PO qd; Info: use w/ GnRH analog in pts w/o bilateral orchiectomy; do not open/dissolve cap; do not cut/crush/chew tab
[metastatic castration-sensitive dz]
Dose: 160 mg PO qd; Info: use w/ GnRH analog in pts w/o bilateral orchiectomy; do not open/dissolve cap; do not cut/crush/chew tab

Renal dosing

[see below]
CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

[no adjustment]

 

SRC: NLM .