Aclasta

Generic Name: zoledronic acid 
Names of brands: Aclasta, Zometa, Reclast

What is Aclasta?

ZOLEDRONIC ACID
ZOLEDRONIC ACID

Aclasta contains zoledronic acid (sometimes called zoledronate). It is part of a family of drugs known as bisphosphonates. Zoledronic acid blocks the absorption of calcium out of bones.

Aclasta can be used to treat Paget’s disease as well as osteoporosis for postmenopausal females.

Aclasta is also employed for purposes that are not mentioned in this guide.

Warnings and Precautions

Don’t take Aclasta without consulting your physician in the event that you’ve experienced reactions to an allergen such as zoledronic acids or similar medications like alendronate (Fosamax) or the etidronate (Didronel) or ibandronate (Boniva) or Pamidronate (Aredia) or risedronate (Actonel) as well as Tiludronate (Skelid).

Do not take Aclasta before telling your physician in case you are expecting. It may cause harm to your unborn child. Make sure you use a safe method of birth control. Also, inform your physician if you develop a pregnancy while receiving treatment.

The doctor might suggest having a dental check-up to determine the need for preventive gum and tooth treatment prior to beginning treatment with Aclasta. This is especially crucial in the case of cancer, are taking chemotherapy or steroids, or suffer from dental problems.

Certain patients who are taking medications like Aclasta have suffered from jaw bone loss which is also known as osteonecrosis of the jaw. Signs of this disease could include jaw discomfort, swelling, numbness, gum inflammation, loose teeth, or slow healing after injuries or surgeries that involve the gums. It is possible to develop osteonecrosis in the jaw if you are suffering from cancer or have had treatment with radiation, chemotherapy, or steroids. Other ailments that are associated with osteonecrosis in the jaw are blood clotting disorders as well as anemia (low red blood cells) and previous dental problems.

In summary :

Prior to receiving Aclasta

aclastaIt is not recommended to take Aclasta in the event that you are allergic to zoledronic acids or similar medications like alendronate (Fosamax) and Etidronate (Didronel) Ibandronate (Boniva) and Pamidronate (Aredia) and risedronate (Actonel) and Tiludronate (Skelid).

Also, you should not get Aclasta If you suffer from:

Zometa, as well as Reclast, are two distinct versions of zoledronic acid. It is not recommended to be treated with Reclast when you’re already receiving Zometa. Before you receive the Reclast injection, inform your doctor that you are currently receiving Zometa.

Before you receive Aclasta tell your physician if you suffer from:

The doctor might suggest having a dental check-up to ensure that you are receiving preventive dental and gum treatment prior to starting treatments with Aclasta. This is particularly important in the case of cancer, are taking chemotherapy or steroids, or are suffering from poor dental health.

Some patients who are taking medications like Aclasta have experienced jaw bone loss which is also known as osteonecrosis of the jaw. Signs of this disease could include jaw pain and swelling, numbness or gum infections, loose teeth, or slow healing following injuries or surgeries that involve the gums.

There is a higher chance to suffer from osteonecrosis of your jaw if you suffer from cancer or have had treatment using radiation, chemotherapy, or steroids. Other ailments that are associated with osteonecrosis in the jaw are blood clotting disorders as well as anemia (low red blood cells) and dental surgery or existing dental issues.

FDA classification for pregnancy D. This medication could harm an unborn child. Don’t take Aclasta without informing your physician when you’re expecting. Make sure you are using a reliable method of birth control and inform your doctor if pregnant while receiving treatment. Aclasta is a substance that can be found in breast milk and could harm nursing babies. Do not take Aclasta without informing your doctor whether you are breastfeeding your baby.

How to take Aclasta?

Aclasta is administered by injection with a needle inserted in the vein. It is administered in a hospital or clinic or in a hospital. The medicine should be administered slowly, via an IV infusion. It can take up to 15 minutes to finish.

Aclasta may be prescribed only every year. Follow the instructions of your physician.

Take at least two glasses of water just a few hours before your injection to prevent becoming dehydrated.

Your physician may ask you to take calcium or vitamin D supplements when you’re receiving treatment for Aclasta. Follow your doctor’s advice regarding the strength and type of calcium that you need to take.

To make sure Aclasta can help your condition and is not producing adverse unwanted side effects the blood of your patient needs to be checked frequently. Your kidney function could be a factor to be checked. It is crucial to do not to miss any appointments with your physician.

Information and usage 

Aclasta is a bisphosphonate that is indicated for the treatment of

Limitations of Use The safety and effectiveness of zoledronic acid injections have been questioned for their use for hyperparathyroidism or other non-tumor-related hypercalcemia.

Dosage and Administration

Hypercalcemia in malignancy 

Multiple myeloma and bone metastasis resulting from solid tumors.

Utilize a separate, vented infusion line. Do not let it come into contact with divalent cation-containing calcium solutions.

Dosage and Strengths

Injection: 4 mg/5mL (0.8 mg/mL) single-dose vial to dilute ahead of intravenous infusion 

If I don’t take the dose?

Consult your physician if you have missed a dose of Aclasta.

If I consume too much?

Contact emergency medical assistance If you suspect you’ve taken excessive Aclasta. The signs of an overdose could include tingling or numbness of your feet or hands and muscle stiffness and spasms in muscles that surround your eyes, irregular heartbeats, wheezing or difficulty breathing.

What to avoid?

Avoid performing any dental procedure while receiving treatment with Aclasta. It could take longer than usual for you to heal.

Aclasta side effects

Contact your doctor immediately If you experience any of the symptoms that indicate an allergic reaction, such as asthmatic hives, difficulty breathing, or swelling of your lips, face, or tongue. Contact your doctor immediately in case you experience any of these severe reactions:

Less severe Aclasta adverse effects could be:

This isn’t a complete list of all side effects. other side effects could occur. Inform your physician about any unusual or unpleasant adverse reaction.

What other medications can impact Aclasta?

Before taking Aclasta to inform your doctor if taking any of the following medicines:

The list below isn’t exhaustive and there are other medications that interfere with Aclasta. Inform your doctor about every prescription and over-the-counter medicine you take. This includes minerals, vitamins or herbal supplements, as well as medications prescribed by doctors. Do not begin taking any new medication without first talking to your physician.

Additional details

 

Leave a Reply