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Generic: Abaloparatide

Brand name: Tymlos
Dosage forms: subcutaneous solution (3120 mcg/1.56 mL)
Class of drugs: Parathyroid hormone and its analogs

What exactly is abaloparatide?


Abaloparatide is a medication used in the treatment of osteoporosis in postmenopausal females who are at an increased chance of fractures of the bone.

Abaloparatide can also be employed for reasons not mentioned in this medication guide.


Abaloparatide is known to cause the development of bone cancer (osteosarcoma) within animals, but it isn’t known if this will occur in those who take abaloparatide. Consult your physician regarding your risk.

Contact your doctor immediately for bones pain, unusual body aches, an unusual lump or swelling under your skin.

Do not smoke cigarettes or drink liquor. Smoking or drinking heavily can decrease the bones mineral content, which makes the risk of fractures higher.

Before taking this medication, you must consult your physician

Abaloparatide is not a good choice in case you have an allergy to it.

Abaloparatide should not be used in young children or adults with bones that are growing.

Speak to your doctor if have ever suffered from:

  • Paget’s Disease or a bone disorder other than osteoporosis
  • excessive blood levels of calcium or alkaline phosphatase
  • overactive parathyroid glands;
  • bone cancer, or radiation treatment for your bones
  • A kidney stone.

Abaloparatide is known to cause osteoporosis (osteosarcoma) within animals, but it isn’t clear if this will occur in patients taking this drug. Discuss with your physician the risk you are taking.

Abaloparatide can be used only in women who can no longer become pregnant. It is unclear if abaloparatide could affect the unborn child. Consult your physician if you suspect you are expecting.

It might not be safe to breastfeed while taking this medication. Consult your physician about any potential risks.

How to take abaloparatide?

Follow the directions on your prescription label, and go through all medication guides and instructions. Make sure you use the medication precisely as directed.

Abaloparatide can be injected under the skin, generally daily, at least once. A doctor may instruct you on how to use the medication on your own.

Be sure to read and adhere to any instructions for use that come in your medication. Talk to your pharmacist or doctor for clarification if you aren’t sure about the instructions.

Do not use the needle, cartridge or syringe even when the needle has altered. Sharing these devices could allow diseases or infections to transfer from one person to the next.

Take the medication, in the same way, each day.

Make an injection only when you are prepared to administer it. Avoid using when the medication appears unclear, changes colour or has particles. Contact your pharmacist to inquire about a new medication.

Only use the injection pen supplied with abaloparatide. Don’t transfer the medication to a syringe, or another injector or you may receive an overdose.

Your physician will tell you the best place you can inject abaloparatide. You should use a different spot every time you administer an injection. Make sure you don’t inject in the same area twice in the same row.

Abaloparatide can cause dizziness. Make sure to inject your medication at a time and in a place in which you can rest or lay down for a short period.

Use a needle or syringe just once, and then put them in a puncture-proof “sharps” container. Make sure you follow local or state laws regarding how to dispose of the container. Make sure it is out of range of pets and children.

Abaloparatide is just one component of a comprehensive treatment plan which includes changes to diet and exercise, as well as taking mineral or vitamin supplements and altering certain behaviour. Follow the instructions of your physician precisely.

Keep empty injection pen within the fridge. Do not put them in the freezer.

When you are ready to use the pen, you should store the pen at room temperatures, away from heat and moisture. Following each usage, take off your needle, and then cover it using the cap of the needle. Don’t store the pen with the needle in it.

Each injection pen that is prefilled includes enough abaloparatide for 30 injections. The pen should be discarded after 30 injections, regardless the pen has some medicine in it.

Abaloparatide is usually prescribed for just 2 years. The doctor you consult will determine the length of time you will be treated with abaloparatide.

If I miss a dose?

Make sure to take the missed dose the same day that you remember it. Make sure to take the next dosage at your regular time and adhere to the daily schedule. Don’t take two doses within a single day.

How do I react if consume too much?

Get medical attention immediately or contact toll-free the Poison Help line at 1-800-222-1222.

The symptoms of an overdose can be headache dizziness, headache vomiting rapid heartbeats, feeling lightheaded or fainting.

What to be aware of?

Be careful not to get up too fast from a lying or sitting posture, as you might get dizzy. Start slowly and steady yourself to avoid falling.

Stop smoking cigarettes, or attempt to stop. Smoking cigarettes can lower your bones mineral content, which makes the possibility of fractures higher.

Do not consume large quantities of alcohol. Alcohol consumption can also lead to loss of bone.

Abaloparatide side effects

Contact a medical professional immediately If you are experiencing symptoms that indicate an allergy such as an allergic reaction that causes hives and breathing problems or swelling of your lips, face and tongue.

Contact your doctor immediately If you are suffering from:

  • Feeling lightheaded, as if you’re about to pass out (may be experienced within the first 4 hours of the injection);
  • bone pain;
  • strange body discomfort;
  • A new or more severe swelling or lump beneath your skin
  • Heartbeats that pound or flutter in your chest, chest pain
  • excessive calcium levels – fatigue, confusion, nausea, nausea, loss of hunger, constipation, more thirst or urination losing weight or
  • signs of kidney stones: severe pain in your lower back or lower back and urine that is bloody painless urine.

Common side effects can be:

  • dizziness, spinning sensation;
  • headache;
  • rapid heart rate;
  • nausea, upper stomach pain; or
  • I am feeling extremely tired.

This isn’t a complete list of possible side effects, and others could happen. Contact your physician for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Abaloparatide dosing information

Usual Adult Dose for Osteoporosis:

80 mcg subcutaneously, once a day

The use of multiple doses of this drug as well as parathyroid hormone analogs (e.g., teriparatide) for longer than two years in the course of a patient’s life is not advised.
Patients should be provided with additional Vitamin D and calcium when the intake of food is not sufficient.

Use: To treat postmenopausal females with osteoporosis at risk of fracture, defined as having the presence of osteoporotic fractures and several risk elements for fractures or patients who have not responded or are not tolerant of other treatment options for osteoporosis; in postmenopausal women suffering from osteoporosis this medication reduces the chance of vertebral fractures as well as non-vertebral fractures.


What other drugs can impact abaloparatide?

Other medications can affect abaloparatide. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor all the medicines you are currently taking as well as any medications you are about to start or stop taking.

Additional details

Keep all medicines away from the reach of children. Do not give your medication to anyone else and take this medication only in the manner prescribed by your doctor.

Always consult your physician to confirm that the information provided on this site is appropriate to your particular situation.

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