Generic Name: testosterone undecanoate
Dosage Form: capsules, for oral use
Medically reviewed by A Ras. Updated on March 31, 2022.
What is Tlando?
Tlando is a prescribed medicine that is a testosterone-based medicine. It is prescribed for adult males with low or no testosterone due to specific medical ailments.
It isn’t known whether this medicine can be used safely or effectively for youngsters younger than 18. Incorrect use of Tlando can impact bone growth in children.
Tlando can be classified as a controlled substance (CIII) because it is a source of testosterone, which can be a target for those who misuse prescription drugs. Keep your Tlando in a safe place to protect it. Do not give it to someone other people even if they suffer from similar symptoms to yours. The act of selling or giving away the medicine could harm other people and is illegal.
Tlando is not designed to be used by women.
TLANDO is an oral capsule containing testosterone undecanoate (TU) and has been developed for the treatment of hypogonadism in adult males. TLANDO is proposed as testosterone replacement therapy (TRT) for the treatment of conditions associated with a deficiency or absence of endogenous testosterone (T) due to primary or hypogonadotropic hypogonadism, as per standard class TRT labeling.
There are various testosterone preparations with different routes of administration available in the United States (US). Each TRT therapy is approved to provide testosterone replacement therapy, but the various TRT agents have unique pharmacokinetic (PK) properties, limitations, risks, and safety concerns. The only oral preparation approved for use in the US is 17-alpha-alkylated drugs that undergo first-pass metabolism and thus pose the risk of hepatotoxicity.
There are several challenges to developing a non-17-alpha alkylated oral testosterone formulation with an adequate PK profile, including providing adequate bioavailability, minimizing food effects, and having low variability in serum concentrations. TLANDO is an oral capsule product containing 112.5 mg of TU and a proprietary formulation composed primarily of non-triglyceride based lipids. TLANDO is designed to enable absorption of TU predominantly via the intestinal lymphatic pathway. Testosterone undecanoate is a prodrug delivered as a straight chain fatty acid ester of testosterone, which is not alkylated at the 17alpha position. After being absorbed via the lymphatics, TU is converted to active testosterone by non-specific esterases. ¶
Currently, TU is available as an injectable product in the US (brand name, Aveed). Oral TU (Andriol) is not approved in the US but has been marketed for more than 20 years outside of the US in more than 80 countries, including Canada, for the treatment of male hypogonadism
Tlando can cause serious side effects, including:
- The blood pressure is rising.
- Tlando may increase blood pressure. This could increase the risk of stroke or heart attack and may increase the chance of dying due to stroke or heart attack. Your risk is increased in the event that you’ve already experienced an attack on your heart or suffered a stroke, or if you have other risk factors that could lead to heart stroke or attack.
- In the event that your blood pressure rises as you treat medications for blood pressure, they could be required to be initiated. If you’re taking blood pressure medications or new blood pressure medication, they could be needed or the current medications for blood pressure might need to be altered to lower your blood pressure.
- When your blood pressure is unable to be maintained, Tlando may need to be removed.
- Your doctor will be monitoring your blood pressure while you are receiving the course of treatment.¶
Who should not be taking Tlando?
Don’t take Tlando If you are:
- are breast cancer patients.
- are suffering from prostate cancer.
- If you are a woman expecting. Tlando may harm your unborn baby.
- Are sensitive are allergic to Tlando or any of the ingredients. Check out the bottom of this page for a full listing of the ingredients.
- suffer from low testosterone, even without medical health conditions. For instance, you should not take Tlando in the event that you suffer from low testosterone as a result of age.
Before taking Tlando
Before starting treatment, inform your physician about your medical conditions, especially the following:
- suffer from high blood pressure or are being treated for high blood pressure.
- Have heart issues.
- are high in red blood cells (hematocrit) or high hemoglobin levels in the laboratory.
- are suffering from urinary problems because of an overly large prostate.
- Have kidney or liver issues.
- are afflicted with a mental illness, such as suicidal thoughts , actions or even depression, anxiety , or mood disorders.
- Have breathing problems when you are sleeping (sleep sleep apnea).
What other drugs can impact Tlando?
Talk to your doctor about the medications you are taking, including prescription and non-prescription medications supplements, vitamins, or herbal remedies.
The use of Tlando together with other medicines could affect one another. Particularly, inform your doctor that you take:
- drugs that inhibit bleeding (blood thinners).
- medications that raise blood pressure like cold and pain medicine.
Make sure you know the medications you take. Consult your doctor or pharmacist for the list of these medications when you’re not certain. Keep a record of these and present it to your doctor and pharmacist whenever you receive an upcoming medication.
How should I take Tlando?
- You should take Tlando tablets exactly according to what your doctor advises you to take it.
- The capsules are taken by mouth twice a day. Take 2 capsules in the early morning and then two capsules at night.
- Consume the capsules along with your food.
Normal Adult Dosage to Treat male hypogonadism
Dosage: 225 mg orally, once a day in conjunction with food
– Comment: Monitor the levels of testosterone in your serum while you are receiving treatment.
– Use: males who are who suffer from conditions that are related to a deficit or absence of testosterone.
Tlando side effects
Tlando may cause serious side effects including:
- Read Important details
- The red blood cells are growing in counts (hematocrit) (also known as hemoglobin).
- Tlando can increase the number of red blood cells in certain people. The high levels of red blood cells increase the chance of strokes, blood clots, and heart attacks.
- It is possible to stop your treatment if you notice that the count of your red blood cells rises.
- Your doctor should examine the count of your red blood cells and hemoglobin level during treatment.
- If you suffer from prostate cancer The symptoms and signs could get worse while taking Tlando.
This could include:
- more frequent urination during the night
- difficulty in launching your urine stream
- The need to urinate several times throughout the day
- The urge to go to the bathroom immediately
- a urine accident
- the inability to pass urine, or weak flow of urine
- Higher chance of developing prostate cancer. Your healthcare provider must check your prostate for cancer or other prostate-related issues before you begin, and also while you are undergoing treatment.
- Blood clots can be found in the lungs and legs. Signs and symptoms of a blood clot on your leg may include swelling, pain or redness. The signs and symptoms that a blood-clot has formed within your lungs could include trouble breathing and chest pain.
- Use. Testosterone can be misused, especially when it is taken in more than the prescribed doses, and in combination in conjunction with other anabolic androgenic steroids. The abuse of steroids can trigger grave heart and psychological side adverse effects. Your doctor should examine to identify signs of abuse prior as well as during your treatment.
- In large doses, Tlando may lower your sperm count.
- Liver issues. The symptoms of liver issues could include:
- Ankle swelling feet, legs, or the body (edema) either whether or not you have heart disease.
- Breasts that are painful or large.
- Breathing problems when you are asleep (sleep air apnea).
Contact your doctor right now if you are experiencing some of the severe side effects mentioned above.
The most frequent adverse reactions include:
- an increase in prolactin levels in your blood
- an increase in weight
- high blood pressure
- chest pain
- an increase in the number of red blood cells
- muscle and joint muscles and joint
- common cold
Contact your healthcare provider in the event of any side effects that bother you or do not disappear.
There are many possible negative side consequences. For more details, consult your doctor or pharmacist.
Consult your physician to seek medical advice on possible side effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.
How to store Tlando?
- Storage Tlando capsules with room temperature, ranging from the 68-77 degF range. (20degC to 25degC).).
- Place your capsules dry in a location.
Make sure that all medications are out of reach of pets and children.
General information on the safetyy of Tlando.
Sometimes, medicines are used for reasons other than the ones listed in the Medication Guide. Don’t use this medication to treat a problem for which it is not recommended. Don’t offer it to anyone else regardless of whether they are suffering from the same symptoms as you do. They could be harmed by it. It is possible to ask your doctor or pharmacist for any information specifically written for health professionals.
What are the main ingredients in Tlando?
Active ingredient: testosterone undecanoate
Ingredients that are inactive: ascorbyl palmitate monoolinoleate of glyceryl, polyethylene glycol 80 and polyoxyl 40 hydrocarbonated castor oil.
Capsule shell contains gelatin, black iron oxide, and titanium dioxide as well as imprint ink (ammonium hydroxide black iron oxide, propylene glycol, and shellac).
Always consult your physician to make sure the information presented on this site is appropriate to your specific situation.