Tlando

Generic Name: testosterone undecanoate
Dosage Form: capsules, for oral use

Medically reviewed by A Ras. Updated on March 31, 2022.

What is Tlando?

Tlando is a prescribed medicine that is a testosterone-based medicine. It is prescribed for adult males with low or no testosterone due to specific medical ailments.

It isn’t known whether this medicine can be used safely or effectively for youngsters younger than 18. Incorrect use of Tlando can impact bone growth in children.

Tlando can be classified as a controlled substance (CIII) because it is a source of testosterone, which can be a target for those who misuse prescription drugs. Keep your Tlando in a safe place to protect it. Do not give it to someone other people even if they suffer from similar symptoms to yours. The act of selling or giving away the medicine could harm other people and is illegal.

Tlando is not designed to be used by women.

Description

TLANDO is an oral capsule containing testosterone undecanoate (TU) and has been developed for the treatment of hypogonadism in adult males.  TLANDO is proposed as testosterone replacement therapy (TRT) for the treatment of conditions associated with a deficiency or absence of endogenous testosterone (T) due to primary or hypogonadotropic hypogonadism, as per standard class TRT labeling.

There are various testosterone preparations with different routes of administration available in the United States (US). Each TRT therapy is approved to provide testosterone replacement therapy, but the various TRT agents have unique pharmacokinetic (PK) properties, limitations, risks, and safety concerns.  The only oral preparation approved for use in the US is 17-alpha-alkylated drugs that undergo first-pass metabolism and thus pose the risk of hepatotoxicity.

Tlando

There are several challenges to developing a non-17-alpha alkylated oral testosterone formulation with an adequate PK profile, including providing adequate bioavailability, minimizing food effects, and having low variability in serum concentrations. TLANDO is an oral capsule product containing 112.5 mg of TU and a proprietary formulation composed primarily of non-triglyceride based lipids.  TLANDO is designed to enable absorption of TU predominantly via the intestinal lymphatic pathway. Testosterone undecanoate is a prodrug delivered as a straight chain fatty acid ester of testosterone, which is not alkylated at the 17alpha position. After being absorbed via the lymphatics, TU is converted to active testosterone by non-specific esterases. 

Currently, TU is available as an injectable product in the US (brand name, Aveed). Oral TU (Andriol) is not approved in the US but has been marketed for more than 20 years outside of the US in more than 80 countries, including Canada, for the treatment of male hypogonadism

Important information

Tlando can cause serious side effects, including:

Who should not be taking Tlando?

Don’t take Tlando If you are:

Before taking Tlando

Before starting treatment, inform your physician about your medical conditions, especially the following:

What other drugs can impact Tlando?

Talk to your doctor about the medications you are taking, including prescription and non-prescription medications supplements, vitamins, or herbal remedies.

The use of Tlando together with other medicines could affect one another. Particularly, inform your doctor that you take:

Make sure you know the medications you take. Consult your doctor or pharmacist for the list of these medications when you’re not certain. Keep a record of these and present it to your doctor and pharmacist whenever you receive an upcoming medication.

How should I take Tlando?

Dosing information

Normal Adult Dosage to Treat male hypogonadism

Dosage: 225 mg orally, once a day in conjunction with food

– Comment: Monitor the levels of testosterone in your serum while you are receiving treatment.

– Use: males who are who suffer from conditions that are related to a deficit or absence of testosterone.

Tlando side effects

Tlando may cause serious side effects including:

Contact your doctor right now if you are experiencing some of the severe side effects mentioned above.

The most frequent adverse reactions include:

Contact your healthcare provider in the event of any side effects that bother you or do not disappear.

There are many possible negative side consequences. For more details, consult your doctor or pharmacist.

Consult your physician to seek medical advice on possible side effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

How to  store Tlando?

Make sure that all medications are out of reach of pets and children.

General information on the safetyy of Tlando.

Sometimes, medicines are used for reasons other than the ones listed in the Medication Guide. Don’t use this medication to treat a problem for which it is not recommended. Don’t offer it to anyone else regardless of whether they are suffering from the same symptoms as you do. They could be harmed by it. It is possible to ask your doctor or pharmacist for any information specifically written for health professionals.

What are the main ingredients in Tlando?

Active ingredient: testosterone undecanoate
Ingredients that are inactive: ascorbyl palmitate monoolinoleate of glyceryl, polyethylene glycol 80 and polyoxyl 40 hydrocarbonated castor oil.
Capsule shell contains gelatin, black iron oxide, and titanium dioxide as well as imprint ink (ammonium hydroxide black iron oxide, propylene glycol, and shellac).

 

Additional details

Always consult your physician to make sure the information presented on this site is appropriate to your specific situation.

Leave a Reply