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Generic name: vedolizumab  

Brand name

In the U.S.

  • Entyvio

Available Dosage Forms:

  • Powder for Solution

Pharmacologic Class: Monoclonal Antibody

Uses for Entyvio

Entyvio (vedolizumab) 

Entyvio injections are employed to help treat Crohn’s disease as well as ulcerative colitis among patients who are not being helped by other medications. This is a monoclonal antigen that targets the immune system.

This medication should be administered only by or under the supervision of your physician.

Before using Entyvio, make sure you are familiar with the following

When you decide to use any medicine, the dangers of taking the medicine have to be considered against the benefits it can do. It is a choice both you and your doctor take. In this case, to be considered, the following factors should be assessed:


Inform your doctor whether you’ve had an unusual reaction or allergic reaction to this medication or any other medications. Be sure to inform your health specialist if you suffer from any other allergies, like to dyes, foods preservatives, animals, or dyes. For products that are not prescription-only, you must review the label or the ingredients on the package carefully.


The right studies haven’t been conducted on the relation of age to the effect of Entyvio in the infant population. Safety and efficacy haven’t been proven.


Studies that are appropriate up to now haven’t revealed the existence of geriatric-specific issues that restrict the use of injecting Entyvio into the older.


There are no studies that are sufficient of women that can determine the risks to babies when taking Entyvio medication while breastfeeding. Consider the benefits and the risk of using this medication during nursing.

Interactions of Entyvio between medicines

Certain medicines shouldn’t be combined in any way however, there are instances where two medicines can be taken together, even if there is a chance of interaction. In these situations, your doctor might want to alter the dosage or make other precautions needed. If you are taking this medication, it is crucial that you let your healthcare provider know they are prescribing any of the drugs that are listed below. These interactions have been determined based on their potential importance and may not be all-inclusive.

Utilizing this medicine in conjunction in conjunction with the following medications is generally not advised, however it may be necessary for certain situations. If two medicines are prescribed at the same time and your doctor recommends a change in the dosage or the frequency you take one or both of the drugs.

  • Anifrolumab-fnia
  • Infliximab
  • Tofacitinib

Interactions of Entyvio with alcohol/food/tobacco/food

Certain medications are not recommended to be taken at or near the time of taking food, or eating specific kinds of food as interactions could happen. The use of tobacco or alcohol together with certain medications can create interactions. Talk with your healthcare provider about your medication’s interactions in conjunction with alcohol, food, or tobacco.

Other medical issues

The presence of any other medical issues could impact the effectiveness of this medication. Be sure to inform your physician if you suffer from any other medical issues including:

  • Infections can reduce your body’s capacity to fight infection.

Proper use of Entyvio

A doctor or another trained medical professional will administer this medication. It is administered through the use of a needle inside your vein.

The medicine must include a Medication, Manual. Follow these directions attentively. Talk to your doctor if have any concerns.

Use with caution when using Entyvio

It is vital to have your doctor monitor your improvement on a regular basis to ensure the medicine is working as it should. Tests for blood may be required to look for any adverse negative effects.

Vedolizumab could trigger an infusion reaction during the time you’re receiving it, or shortly after the infusion has ended. Talk to your doctor or nurse immediately if you feel chest pain, fever or chills, itching, the appearance of hives, a rash fainting, dizziness, and lightheadedness. You may also experience headache or joint pain, trouble swallowing, difficulty breathing, or swelling of your tongue, face, and throat.

This medication can cause serious allergic reactions, which could include anaphylaxis. Anaphylaxis could be life-threatening and requires immediate medical care. Get your doctor’s attention immediately in case you notice an itchy, rash, or breathing problem, difficulty swallowing, or swelling in your face, hands, or mouth that is caused by this medicine.

The body’s ability to fight infection could be diminished by this medication. Beware of people who are sick, and clean your hands frequently. Contact your physician if you have ever suffered from an infection that didn’t disappear or which kept coming back. Consult your physician immediately if you experience symptoms of fever, chills flu-like symptoms or cough, or unusual weakness or tiredness.

This medication may increase the risk of contracting a rare brain disease called Progressive Multifocal Leukoencephalopathy (PML). Consult your physician immediately in case you experience back pain, blurred vision dizziness, confusion or drowsiness, headache or fever or seizures, or sudden weakness or fatigue.

Consult your physician right immediately if you experience discomfort or tenderness in your upper stomach and stools that are pale or dark urine, a loss of appetite nausea, vomiting, or yellow skin or eyes. These may be signs of a liver issue that is serious.

While you’re being treated with vedolizumab, you must not get any vaccinations (vaccines) without the approval of your physician. Your vaccinations must be up-to-date prior to receiving the treatment vedolizumab.

Don’t take any other medication in the absence of discussing with your physician. This includes prescription and non-prescription (over-the-counter OTC) medications as well as herbal or vitamin supplements.

Entyvio side effects

Alongside its necessary effects, medicines can result in unwanted adverse effects. Although not all adverse effects can occur, if they occur, they might require medical attention.

Consult your physician or nurse right awayif you experience any of these side effects happen:

More popular

  • The body is aching or hurting
  • chills
  • trouble breathing
  • Ear congestion
  • febrile
  • headache
  • Loss of voice
  • nasal congestion
  • runny nose
  • Snorting
  • sore throat
  • unusual weakness or fatigue

Less popular


  • Cough
  • difficulties swallowing
  • dizziness
  • fast heartbeat
  • itching, hives or skin itching, or a rash
  • The swelling or puffiness of the eyelids, around the eyes or lips or the tongue
  • The chest is tight

Incidence unknown

  • Pain in the stomach or abdomen
  • blurred vision
  • stool with a clay-colored color
  • confusion
  • convulsions
  • Dark urine that is dark
  • Drowsiness
  • headache
  • Loss of appetite
  • Lower back or side discomfort
  • uncomfortable or painful urination
  • Unpleasant breath smell
  • Vomiting of blood
  • Skin or eyes with yellow eyes

There are some side effects that can occur which usually don’t require medical care. These side effects can be eliminated after treatment, as the body adapts to the medication. Additionally your health professional might be able to inform you on how to prevent or minimize the effects of these adverse effects. Talk to your doctor in the event that any of these symptoms persist or become uncomfortable or if there are any concerns about these:

More commonly

  • Moving is difficult for me.
  • Muscle pain or stiffness
  • joint pain

Other adverse side effects that are not listed can also occur in certain patients. If you observe any other symptoms, consult with your doctor.

Contact your physician for advice from a medical professional regarding possible side effects. You can report any adverse reactions directly to FDA at 1-800-FDA-1088


  • Entyvio side effects  (detailed information)


For more information

Always consult your physician to make sure the information presented on this page is applicable to your particular situation.


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