Dupixent Side Effects

 

The generic name is dupilumab

 

Summary

Dupixent Side Effects
Dupixent

The side effects that occur require immediate medical care

In addition to its beneficial effects In addition to its necessary effects, dupilumab (the active ingredient found within the drug Dupixent) could cause undesirable effects. While none of these adverse effects can be present, if they do occur, they might require medical care.

Talk to your doctor immediately If any of these side effects happen while you are taking Dupixent:

More commonly

Less popular

Rare

There are no immediate side effects that require medical treatment

A few side effects from Dupixent can occur, but they usually don’t require medical care. These Dupixent side effects can disappear when the body adapts to taking the medication. Also, your healthcare expert may give you suggestions to reduce or eliminate certain adverse negative effects.

Talk to your physician If any of the following adverse effects persist or become bothersome or If you have questions regarding these side effects:

More commonly

Less well-known

Managing Dupixent side effects (general information)

For Healthcare Professionals

It is applicable to dupilumab Subcutaneous solution

General

A few of the most commonly reported adverse reactions have been reactions at the injection site, conjunctivitis, eye pruritus or oral herpes other herpes virus infections, oropharyngeal discomfort, and eosinophilia.

Cardiovascular

Uncommon (0.1 to 1% to 1.1%) (Circular thromboembolic events) (cardiovascular deaths and non-fatal myocardial ischemias as well as nonfatal strokes)

In a placebo-controlled study for adolescents and adults who suffer from asthma heart disease, cardiovascular thromboembolic complications (cardiovascular deaths as well as non-fatal myocardial ischemias as well as nonfatal strokes) were observed in one (0.2 percent) patient who was taking the drug at 200 mg twice a week 4 (0.6 percent) patients who received 300 mg every two weeks, and in 2 (0.3 percentage) patients from the placebo group.

Local

Very frequent (10 10% or more) Site reactions to injection (10 percent) 

Ocular

Very frequent (10 percent or more) Conjunctivitis (cluster comprises conjunctivitis and allergic conjunctivitis and bacteria conjunctivitis viral conjunctivitis, massive papillary conjunctivitis, and eye inflammation) (10 10 percent)

Common (1% to 10%): Blepharitis, eye pruritus, keratitis (e.g., keratitis, ulcerative keratitis, allergic keratitis, atopic keratoconjunctivitis, ophthalmic herpes simplex), dry eye

Immunologic

The most common (1 10% to 10 percent) Herpes Simplex Viral infections (e.g. herpes simplex or genital herpes simplex Otitis externa Herpes virus) and immunogenicity

Very uncommon (less then 0.01 percent) Serum sickness/serum-sickness-like reactions

Hypersensitivity

Uncommon (0.1% to 1%): Hypersensitivity

Gastrointestinal

The most common (1 10% to 10 10%) Oral herpes oropharyngeal pains, toothache, gastritis 

Hematologic

A few cases of vasculitis which are associated with polyangiitis and eosinophilic granulomatosis have been observed in adult patients who took part in the

asthma and asthma with chronic rhinosinusitis and nasal polyposis clinical studies.

Common (1% to 10%): Eosinophilia

Frequency not disclosed Eosinophilic granulomatosis accompanied by polyangiitis

Nervous system

Common (1% to 10%): Headache 

Psychiatric

Common (1% to 10%): Insomnia

Musculoskeletal

Common (1% to 10%): Arthralgia

Respiratory

Frequency not disclosed: Eosinophilic pneumonia

The cases of eosinophilic pneumonia were observed in patients of adult age who were part of the asthma trials.

Additional details

Always consult your physician to confirm that the information provided on this page is applicable to your specific situation.

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