Istodax Dosage
Istodax Dosage Generic name: romidepsin Drug class: Histone deacetylase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Cutaneous T-cell lymphoma, refractory [14 mg/m^2/dose IV x1 on days 1, 8, 15 of 28-day cycle] Peripheral T-cell lymphoma, refractory [indication withdrawn in US] Info: drug not shown to improve survival in pts w/ […]
Istradefylline Dosage
Istradefylline Dosage Generic name: istradefylline Brand name: Nourianz Dosage form: oral tablet (20 mg; 40 mg) Drug class: Miscellaneous antiparkinson agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 20 mg, 40 mg Parkinson dz, adjunct tx [20 mg PO qd] Max: 40 mg/day; Info: use w/ carbidopa/levodopa; give 40 mg PO qd if >20 […]
Isturisa Dosage
Isturisa Dosage Generic name: osilodrostat Drug class: Adrenal corticosteroid inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 1 mg, 5 mg, 10 mg Cushing disease [2-7 mg PO bid] Start: 2 mg PO bid, then may incr. dose by 2-4 mg/day no more frequently than q2wk; Max: 60 mg/day; Info: for pts ineligible […]
Isuprel Dosage
Isuprel Dosage Generic name: isoproterenol injection Drug classes: Adrenergic bronchodilators, Catecholamines, Vasopressors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ ACLS, bradycardia [2-10 mcg/min IV] Info: for pts unresponsive to atropine or if atropine use inappropriate or w/ beta blocker or calcium channel blocker overdose or awaiting pacemaker; see ACLS: Bradycardia table Heart block [2-20 […]
Ivermectin Dosage
Ivermectin Dosage Generic name: ivermectin (oral) Brand name: Stromectol Drug class: Anthelmintics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 3 mg Strongyloidiasis [0.2 mg/kg/dose PO x1] Info: give on empty stomach Onchocerciasis [0.15 mg/kg/dose PO x1] Info: may repeat in 3-12mo; give on empty stomach Scabies, non-crusted [0.2 mg/kg/dose PO q2wk x2 […]
Ixazomib Dosage
Ixazomib Dosage Generic name: ixazomib Brand name: Ninlaro Dosage form: oral capsule (2.3 mg; 3 mg; 4 mg) Drug class: Proteasome inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 2.3 mg, 3 mg, 4 mg Multiple myeloma, relapsed or refractory [4 mg PO x1 on days 1, 8, 15 of 28-day cycle] Info: […]
Ixempra Dosage
Ixempra Dosage Generic name: ixabepilone Drug class: Mitotic inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Breast CA, locally advanced or metastatic [40 mg/m^2/dose IV x1 on day 1 of 21-day cycle] Max: 88 mg/dose; Info: use w/ capecitabine in pts whose dz is resistant to an anthracycline and a taxane, […]
Ixiaro Vaccine Dosage
Ixiaro Vaccine Dosage Generic name: Japanese encephalitis virus vaccine (SA14-14-2) Drug class: Viral vaccines Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Immunization [18-65 yo] Dose: 0.5 mL IM x2 doses 4wk apart; Alt: 0.5 mL IM x2 doses 7 days apart; Info: for pts w/ high risk of Japanese encephalitis virus exposure; […]
Ixinity Dosage
Ixinity Dosage Generic name: coagulation factor IX Brand names: AlphaNine SD, Alprolix, BeneFIX, Idelvion, Ixinity Drug class: Miscellaneous coagulation modifiers Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Hemophilia B [bleeding episode, minor] Dose: individualize dose IV q24h x1-3 days until healing achieved; Info: estimated dose (units) = [wt (kg) x desired factor IX level […]
Jadenu Dosage
Jadenu Dosage Generic name: deferasirox Brand names: Jadenu, Jadenu Sprinkle Drug class: Chelating agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 90 mg, 180 mg, 360 mg Iron overload, chronic transfusional [14-21 mg/kg/dose PO qd] Start: 14 mg/kg/dose PO qd; Max: 28 mg/kg/day; Info: adjust dose by 3.5-7 mg/kg/day q3-6mo based on serum […]