Isuprel Dosage

Generic name: isoproterenol injection
Drug classes: Adrenergic bronchodilators, Catecholamines, Vasopressors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

ACLS, bradycardia

[2-10 mcg/min IV]

Info: for pts unresponsive to atropine or if atropine use inappropriate or w/ beta blocker or calcium channel blocker overdose or awaiting pacemaker; see ACLS: Bradycardia table

Heart block

[2-20 mcg/min IV]

Start: 5 mcg/min IV; Alt: 0.02-0.06 mg IV x1, then 0.01-0.2 mg IV prn; 0.2 mg IM x1, then 0.02-1 mg IM prn; 0.2 mg SC x1, then 0.15-0.2 mg SC prn; 0.02 mg intracardiac INJ x1

Adams-Stokes attacks

[2-20 mcg/min IV]

Start: 5 mcg/min IV; Alt: 0.02-0.06 mg IV x1, then 0.01-0.2 mg IV prn; 0.2 mg IM x1, then 0.02-1 mg IM prn; 0.2 mg SC x1, then 0.15-0.2 mg SC prn; 0.02 mg intracardiac INJ x1

Shock or hypoperfusion states

[0.5-30 mcg/min IV]

Bronchospasm during anesthesia

[0.01-0.02 mg IV prn]

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Special Note

[dosing clarification]

Info: Adult IV infusion doses expressed in mcg/min, while Peds IV infusion doses expressed in mcg/kg/min

Heart block

[0.05-2 mcg/kg/min IV]

Start: 0.05 mcg/kg/min IV, incr. by 0.1 mcg/kg/min q5-10min; Max: 2 mcg/kg/min

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .