Mekinist Dosage
Mekinist Dosage Generic name: trametinib Drug class: Multikinase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 0.5 mg, 2 mg Melanoma [adjuvant tx] Dose: 2 mg PO qd for up to 1y; Info: for pts w/ BRAF V600E or V600K mutation; use w/ dabrafenib; give at least 1h before or 2h […]
Mektovi Dosage
Mektovi Dosage Generic name: binimetinib Drug class: Multikinase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 15 mg Melanoma, unresectable or metastatic [45 mg PO q12h] Info: for pts w/ BRAF V600E or V600K mutation; use w/ encorafenib Renal dosing renal impairment: no adjustment HD/PD: not defined Hepatic dosing [adjust dose […]
Midostaurin Dosage
Midostaurin Dosage Generic name: midostaurin Brand name: Rydapt Drug class: Multikinase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 25 mg FLT3-positive AML, newly diagnosed [induction tx] Dose: 50 mg PO bid on days 8-21 of each cycle; Info: part of multi-drug chemo regimen; give w/ food [consolidation tx] Dose: 50 mg […]
Menopur Dosage
Menopur Dosage Generic name: follicle stimulating hormone and luteinizing hormone (intramuscular route, subcutaneous route) Drug class: Gonadotropins Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ: 75 units per mL Assisted reproductive technology [w/ no urofollitropin] Dose: individualize dose SC qd; Start: 225 units SC qd x5 days, then may adjust by up to […]
Menostar Dosage
Menostar Dosage Generic name: estradiol transdermal Drug class: Estrogens Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: PATCH: 0.014 mg per day Osteoporosis prevention, postmenopausal [apply 1 patch qwk] Info: weigh estrogen tx risk/benefit; consider adding progestin if intact uterus Renal dosing renal dz: not defined, caution advised HD/PD: not defined, caution advised Hepatic […]
Mephyton Dosage
Mephyton Dosage Generic name: Phytonadione Tablets Drug classes: Anticoagulant reversal agents, Vitamins Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 5 mg Hypoprothrombinemia [vitamin K deficiency] Dose: 2.5-25 mg PO x1; Info: may repeat in 6-8h based on INR; subsequent doses and frequency based on INR [anticoagulant-induced] Dose: 2.5-10 mg PO x1; Info: may […]
Mepron Dosage
Mepron Dosage Generic name: atovaquone Drug class: Miscellaneous antibiotics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: SUSP: 750 mg per 5 mL PCP prophylaxis [1500 mg PO qd] Info: not 1st-line agent; give w/ food PCP tx, mild-mod. [750 mg PO bid x21 days] Info: not 1st-line agent; give w/ food Toxoplasmosis prophylaxis, […]
Meropenem Dosage
Meropenem Dosage Generic name: meropenem Brand names: Merrem, Merrem Novaplus Drug class: Carbapenems Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Skin/skin structure infections, complicated [non-pseudomonal infections] Dose: 500 mg IV q8h [pseudomonal infections] Dose: 1 g IV q8h Intra-abdominal infections, complicated [1 g IV q8h] Febrile neutropenia [1 g IV q8h] Pneumonia [hospital-acquired […]
Merrem Dosage
Merrem Dosage Generic name: meropenem Drug class: Carbapenems Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Skin/skin structure infections, complicated [non-pseudomonal infections] Dose: 500 mg IV q8h [pseudomonal infections] Dose: 1 g IV q8h Intra-abdominal infections, complicated [1 g IV q8h] Febrile neutropenia [1 g IV q8h] Pneumonia [hospital-acquired or ventilator-assoc.] Dose: 1 […]
Methazolamide Dosage
Methazolamide Dosage Generic name: methazolamide Brand names: Neptazane, Glauctabs, MZM Drug class: Carbonic anhydrase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 25 mg, 50 mg Glaucoma [50-100 mg PO bid-tid] Info: for open-angle, secondary, or preop use in acute angle-closure glaucoma Altitude sickness [150-200 mg PO qd] Essential tremor [50-75 mg PO […]