Menopur Dosage

Generic name: follicle stimulating hormone and luteinizing hormone (intramuscular route, subcutaneous route)
Drug class: Gonadotropins

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ: 75 units per mL

Assisted reproductive technology

[w/ no urofollitropin]
Dose: individualize dose SC qd; Start: 225 units SC qd x5 days, then may adjust by up to 75-150 units/day no more frequently than q2 days; Max: 225 units/day for start dose, 450 units/day for subsequent doses; Info: use lowest effective dose
[w/ urofollitropin]
Dose: individualize dose SC qd; Start: 75 units or 150 units SC qd x5 days, then may adjust dose by up to 75-150 units/day no more frequently than q2 days; Max: 225 units/day for total urofollitropin and menotropins start dose, 450 units/day for total combined subsequent doses; Info: use lowest effective dose

Ovulation induction

[step-up regimen]
Dose: individualize dose SC qd; Start: 37.5-75 units SC qd x14 days, then may incr. by 37.5 units/day no more frequently than qwk; Max: 225 units/day; Info: use lowest effective dose
[step-down regimen]
Dose: 150 units SC qd until dominant follicle development, then decr. to 112.5 units/day x3 days, then decr. to 75 units/day

Spermatogenesis induction

[individualize dose SC 3x/wk]
Start: 75-150 units SC 3x/wk; Max: 300 units 3x/wk; Info: use lowest effective dose; use w/ hCG

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

 

SRC: NLM .