Abrilada

 

Generic name: adalimumab  (Subcutaneous route)
Drug class: Antirheumatics, TNF alfa inhibitors

Abrilada is a tumour necrosis factors (TNF) inhibitor that decreases the impact of a chemical in the body that may cause inflammation.

Brand Names

In the U.S.

Available Dosage Forms:

Therapeutic Class: Antirheumatic

Pharmacologic Class: Monoclonal Antibody

Uses for Abrilada

Abrilada
Abrilada

Abrilada injections are used to treat symptoms and stop the progression of active rheumatoid arthritis as well as ankylosing spondylitis. It is prescribed to young children age 2 or older to treat juvenile Idiopathic Arthritis. The medicine can also be utilized to manage psoriatic arthritis which is a kind of arthritis that causes swelling and pain in joints, as well as areas of skin that are scaly that appear on specific parts of the body. Psoriatic arthritis typically manifests as an inflammatory skin condition called Psoriasis. Adalimumab can be administered on its own or in conjunction with other medications (eg methotrexate, DMARDs, and DMARDs).

Abrilada injections are also utilized to treat symptoms of Crohn’s disease that is active in adults and children 6 years old or older who haven’t been treated with other medications such as infliximab. It can also be used for treating moderate to severe ulcerative colitis in adults as well as children aged 5 years and over who have been treated with other drugs (eg corticosteroids, azathioprine or 6-mercaptopurine) which did not perform as well.

Abrilada injections can also be employed to combat chronic plaque psoriasis which is a skin condition that causes white and red spots that don’t go away. It can also be used to treat severe to moderate hyperhidrosis, a chronic skin condition that causes small, painful lumps underneath the skin for adults and children of age or older. It is also employed to manage non-infectious intermediate panuveitis and posterior sclerosis in children and adults aged 2 years and above.

This medication is only available on prescription from your physician.

Prior to using Abrilada,

In making a decision to take a medication, the potential risks of using the medication must be evaluated against the good it can do. This is a choice that you and your physician take. In this case, to be considered, the following factors should be assessed:

Allergies

Discuss with your physician If you’ve ever experienced an unusual reaction or reaction to this medication or any other medication. Inform your health care specialist if you suffer from any other allergies, like dyes, food preservatives, animals, or dyes. For non-prescription medications, look over the label or ingredient list carefully.

Pediatric

The studies that have been conducted so far have not revealed issues that are specific to children, which could hinder the efficacy of adalimumab to the treatment of juvenile idiopathic arthritis as well as non-infectious Uveitis in children aged 2 years of age or older to aid in treatments for the management of Crohn’s disease in children aged 6 years old or older as well as to aid in the treatment of ulcerative colitis in children 6 years old and older, for the cure of ulcerative colitis in children five years old and over or to aid in use in the treatment of hidradenitis-suppurativa for children 12 years of old and over.

However, safety and effectiveness are not known for children younger than 2 years old for juvenile idiopathic arthritis or non-infectious Uveitis, in children who are younger than 5 years old in the case of ulcerative colitis for children younger than 6 years old for Crohn’s disease children who are younger than 12 years of age with hidradenitis suppurativa as well as in children with different conditions.

Geriatric

The studies that have been conducted up to now haven’t revealed specific geriatric issues that could restrict the use of adalimumab for the elderly. However, this medication could cause serious illnesses and cancer particularly in older people that may need to be supervised for patients who receive an injection of adalimumab.

Breastfeeding

There aren’t enough research studies of women that can determine the risk to infants when taking this medication while breastfeeding. Consider the benefits and the risk of using this medication during nursing.

Interactions with medications

While certain medications should not be taken together, however, there are instances where two medicines can be taken together, even if interactions could occur. In these situations, the doctor may decide to alter the dosage or make other precautions needed. If you are taking this medication it is essential to inform your healthcare provider that you are using any one of these medications mentioned below.

The following interactions were determined based on their potential impact and are not meant to be comprehensive.

Combining this medication in conjunction with the following medications is generally not advised, however it may be required in certain instances. If two medicines are prescribed in conjunction and your doctor recommends a change in the dosage or frequency you take one or both of the medications.

Interactions with food, tobacco and alcohol

Certain medications shouldn’t be used during or in conjunction with taking food, or eating specific kinds of food, as interactions can happen. Smoking or drinking alcohol in conjunction together with certain medications can create interactions. Talk with your healthcare provider about the interaction of your medication when you are taking it with alcohol, food, or tobacco.

Other medical conditions

The presence of any other medical conditions could affect the effectiveness of this medication. It is important to inform your physician if you suffer from any other medical conditions including:

Proper use of Abrilada

This section provides details on the proper usage of several products that contain the ingredient adalimumab. It might not be applicable to Abrilada. Be sure to read the article with care.

The Abrilada is administered in the form of a shot that is injected under your skin. Adalimumab is sometimes administered in the home of patients that do not require to visit a clinic or hospital. If you’re taking the medicine from home, the physician or nurse will instruct you on how to prepare and inject the drug. Make sure you know how to utilize the medicine.

The medicine includes the Medication Guide and patient instructions for use leaflet. Follow the directions carefully. Talk to your doctor if have any concerns.

If you decide to use this medicine at home it will show you the body parts where this shot is available. You should use a different area of your body every time you give your child or yourself an injection. Be aware of the location you administer each shot to ensure you rotate your body parts. This will prevent skin issues.

Avoid injecting in areas of your skin that are bruised, red or hard. They may be tender or even hard. If you suffer from psoriasis don’t inject it into an enlarged, thick or red skin patch or lesions.

Abrilada is available in two types. You can utilize either a pen or a prefilled Syringe.

To make use of to use the pen or syringe:

Dosing

The dosage of Abrilada is different depending on the patient. Follow the doctor’s instructions or the instructions printed on your prescription. The information below is only the doses that are typical of this medication. If your dose differs you should not alter it unless your doctor instructs you to change it.

The quantity of medication you consume is contingent on how strong the drug is. In addition, the number of doses you will take every day, the interval between doses, as well as the duration of time that you use the medicine depend on the medical condition that you’re treating with the medication.

Missed dose

If you have missed the dose of this medication make sure you take it as quickly as you can. But, if it’s close to the time for the next dose, you can skip the missed dose and then go back to your usual dose schedule. Don’t double dose.

Storage

Keep your items out of children’s reach.

Avoid keeping outdated medicines or medications that are no longer needed.

Consult your physician about what you can do with any medication you don’t make use of.

Keep your food in the refrigerator. Do not freeze.

Store the medicine in the original container to shield it from light. Avoid using it if it’s been frozen or frozen or thawed. If you’re travelling, you can keep this medicine at room temperature for up to 14 days. Discard any medicine that is not used in 14 days. Don’t store the medicine in extreme cold or heat temperatures.

Dispose of used syringes and pen in a solid closed container, which the needles won’t get through. Keep the container clear of pets and children.

 

Safety precautions when using Abrilada

If you plan to use this medication for a long duration, it is very vital that your doctor monitor your child’s or your own progress regularly. This will allow your physician to determine if the medication is working correctly and determine whether or not you should keep using it. Urine and blood tests could be required to determine undesirable adverse effects.

Your child or you may require an examination of the skin for tuberculosis prior to using this medication. Inform your doctor that you or anyone else within your household has ever experienced a positive reaction after tuberculosis skin tests.

Adalimumab will temporarily reduce the amount of cells called white present in your blood. This could increase the risk of contracting an infection. It may also decrease the number of platelets that are essential for blood clotting. If this happens it is important to take certain precautions you can follow, particularly those with a lower blood count to decrease the chance of bleeding or infection:

Do not take any other medications until they’ve been discussed with your physician. using abatacept (Orencia(r)) or anakinra (Kineret(r)) along with this medication may increase the risk of severe adverse negative effects.

The medicine could cause undesirable effects that do not manifest until months or even years after this medication is administered. There are a few individuals (including teenagers and children) who have taken this kind of medication have been diagnosed with specific types of cancer (eg leukemia, for example).

Certain patients have also been diagnosed with a rare form of cancer, known as lymphoma. Consult your physician in the event that either you or your kid has strange bleeding, bruises or weakness, swelling of lymph nodes on your neck or underarms or groin area, or unresolved weight loss. Additionally, talk to your doctor immediately in the event that your child’s skin bumps that are red, scaly or bumps that have a lot of pus.

Adalimumab can cause severe allergic reactions (eg anaphylaxis or angioneurotic edema) that could be life-threatening and require immediate medical treatment. Consult your physician right now in the event that the child or you has an illness that makes swallowing difficult dizziness, fast heartbeat or a large, hive-like swell around the eyes, face and lips, tongue and the throat, hands, legs feet, sex organs and a rash, itching, difficulties breathing, or weakness or fatigue after you’ve received the medication.

Talk to your doctor now if you notice that either you or your kid is suffering from swelling in the feet, face, fingers or lower legs or suddenly increased weight. This could be a sign of a heart problem known as congestive heart insufficiency (CHF).

A few people who used this medication developed symptoms resembling lupus after treatment but improved after stopping the medication. Consult your physician right now if you notice that the child or you starts suffering from chest pains, joint pains or a rash that appears on the arms or cheeks that are sensitive to sunlight.

Don’t have an active vaccine (immunizations) when either you or your kid is receiving treatment with Adalimumab. The vaccines your child is required to be up-to-date prior to applying the drug adalimumab. It is important to consult your child’s physician if you have any concerns regarding this.

The needle covers of certain pen and syringes that are prefilled are made of natural rubber that is dry (a form of latex) and can cause allergic reactions in those who are allergic to latex. Inform your physician if you or your child suffer from allergies to latex before taking this medication.

Severe skin reactions may occur when using this medication. Talk to your doctor in the event that either you or your kid is suffering from peeling, blistering, or loosening of the skin acne-like red skin lesions, skin rash or acne and ulcers or sores in the face, fever or chills when using this medication.

Don’t take other prescriptions in the absence of discussing with your physician. This includes prescription and other non-prescription (over-the-counter OTC) medicine, herbal and vitamin supplements.

Abrilada side effects

In addition to the beneficial effects, some medicines may produce unwanted side negative effects. Although not all negative side effects are likely to occur, if they occur, they could require medical attention.

Consult your physician immediately in the event that any of these adverse effects happen:

More commonly

Less popular

Incidence unknown

Certain side effects can be experienced which usually don’t require medical treatment. These side effects can be eliminated after treatment, as your body adjusts the medication. Additionally your health professional might be able to inform you how to prevent or minimize the effects of these adverse effects. Consult your physician in the event that any of these adverse effects persist or are troubling or if there are any concerns about these:

More commonly

Less popular

Other side effects that aren’t mentioned could also be present in certain patients. If you experience any other side effects, you should consult with your physician.

Consult your physician to seek medical advice on possible side effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

More details

Always consult your doctor to confirm that the information provided on this page is applicable to your particular situation.

 

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