Suprane Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: VOLATILE LIQUID
General anesthesia induction
- [MAC in 100% oxygen]
- Dose: individualize dose; Start: 3%, incr. by 0.5-1% q2-3 breaths prn; Info: cough/excitation may limit induction speed; end tidal conc. 4-11% produces surgical anesthesia x2-4min; MAC in 25 yo = 7.3%, in 45 yo = 6%, in 70 yo = 5.2%; blood/gas partition coefficient (37C) = 0.42
- [MAC in 60% nitrous oxide/40% oxygen]
- Dose: individualize dose; Start: 3%, incr. by 0.5-1% q2-3 breaths prn; Info: cough/excitation may limit induction speed; end tidal conc. 4-11% produces surgical anesthesia x2-4min; MAC in 25 yo = 4%, in 45 yo = 2.8%, in 70 yo = 1.7%; blood/gas partition coefficient (37C) = 0.42
General anesthesia maintenance
- [MAC in 100% oxygen]
- Dose: individualize dose, typical range 2.5-8.5%; Info: titrate inhalation to effect; MAC in 25 yo = 7.3%, in 45 yo = 6%, in 70 yo = 5.2%; blood/gas partition coefficient (37C) = 0.42
- [MAC in 60% nitrous oxide/40% oxygen]
- Dose: individualize dose, typical range 2.5-8.5%; Info: titrate inhalation to effect; MAC in 25 yo = 4%, in 45 yo = 2.8%, in 70 yo = 1.7%; blood/gas partition coefficient (37C) = 0.42
Renal dosing
- renal impairment: no adjustment
- HD/PD: not defined
Hepatic dosing
- [no adjustment]
SRC: NLM .