Sabril Dosage

Generic name: vigabatrin
Brand names: Sabril, Vigadrone
Drug class: Gamma-aminobutyric acid analogs

Medically reviewed by  A Ras MD

 Recommended Adult Dosing

Dosage forms:  INJ (auto-injector): 22 mcg, 44 mcg; INJ (pre-filled syringe): 22 mcg per 0.5 mL, 44 mcg per 0.5 mL; auto-injector convenience pack; pre-filled syringe convenience pack

Multiple sclerosis, relapsing forms

[44 mcg SC 3x/wk]

Start: 8.8 mcg SC 3x/wk x2wk, then 22 mcg SC 3x/wk x2wk, then 44 mcg SC 3x/wk; Alt: start 4.4 mcg SC 3x/wk x2wk, then 11 mcg SC 3x/wk x2wk, then 22 mcg SC 3x/wk; Info: for pts w/ clinically isolated syndrome, relapsing-remitting dz, and active secondary progressive dz; give doses >48h apart

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: caution advised

SRC: NLM .