Plavix Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 75 mg, 300 mg
Acute coronary syndrome
- [75 mg PO qd]
- Start: 300 mg PO x1; Info: give w/ aspirin 75-325 mg PO qd; may use w/ heparin acutely; consider CYP2C19 genotyping; consider holding tx >5 days before surgery
Thrombotic event prevention
- [75 mg PO qd]
- Info: for pts w/ recent MI, recent stroke, or peripheral arterial dz; consider CYP2C19 genotyping; consider holding tx >5 days before surgery
Renal dosing
- [see below]
- CrCl >60: no adjustment; CrCl <60: not defined, caution advised
- HD/PD: not defined
Hepatic dosing
- [no adjustment]
Recommended Peds Dosing
- Dosage forms: TAB: 75 mg, 300 mg
TIA/thromboembolic stroke prevention
- [<2 yo]
- Dose: 0.2 mg/kg/dose PO qd; Max: 75 mg/day; Info: refer to ACCP guidelines or institution protocols for details on appropriate use
- [2 yo and older]
- Dose: 1 mg/kg/dose PO qd; Max: 75 mg/day; Info: refer to ACCP guidelines or institution protocols for details on appropriate use
Renal dosing
- [not defined]
- renal impairment: consider adult renal dosing for guidance
- HD/PD: not defined
Hepatic dosing
- [not defined]
- hepatic impairment: consider adult hepatic dosing for guidance
SRC: NLM .