Pegvisomant Dosage

Generic name: pegvisomant
Brand name: Somavert
Drug class: Growth hormone receptor blockers

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ: 10 mg per mL, 15 mg per mL, 20 mg per mL, 25 mg per mL, 30 mg per mL

Restricted Distribution in US

Acromegaly

[10-30 mg SC qd]
Start: 40 mg SC x1 on day 1, then 10 mg SC qd; Max: 30 mg/day; Info: may adjust dose by 5 mg/day q4-6wk based on IGF-1 levels

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[no adjustment]
baseline LFTs >3x ULN: weigh risk/benefit

SRC: NLM .