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Leqvio (Inclisiran)


Generic name: inclisiran (Subcutaneous route)


Brand names

In the U.S.

  • Leqvio

Available Dosage Forms:

  • Solution

Therapeutic Class: Antihyperlipidemic

Uses for Leqvio

Leqvio (Inclisiran)

Leqvio injections are administered in conjunction with a balanced diet in conjunction with other medications (eg statins) to treat the condition of heterozygous familial high cholesterol (HeFH) and clinical atherosclerotic coronary disease (ASCVD) for patients who require further reduction in their LDL cholesterol.

This medication should be administered only under the supervision of your physician.

Before making use of Leqvio

When deciding whether to take any medicine, the dangers of using the medication should be evaluated against the positive effects it could bring. This is a decision that you as well as your physician make. To determine the appropriate medicine it is important to take the following into taken into consideration:


Inform your doctor whether you’ve had an unusual or unrelated reaction to this medication or any other medication. Inform your health care doctor if you are suffering from other kinds of allergies, like dyes, food preservatives, animals, or dyes. For non-prescription medications, review the label or the ingredients on the package carefully.


Studies have not been conducted to determine the relationship of age to the effect of the Leqvio injection on the children’s population. The safety and effectiveness of the drug have not been established.


Studies that are appropriate up to now haven’t revealed specific geriatric issues that could restrict the use of the injection of Leqvio for older people. However, older patients are more susceptible to the effects of this medication as compared to younger adults.


There aren’t enough studies on women to determine the risk to infants when taking this medication while breastfeeding. Consider the benefits and the risks that could be associated with using this medication during nursing.

Interactions with medications

While certain medications should not be combined in any way, however, there are instances where two medicines can be combined even though there is a chance of interaction. In these instances, the doctor may decide to alter the dosage or take other precautions if needed. Inform your healthcare provider that you’re having any additional prescriptions or non-prescription (over-the-counter [OTCor over-the-counter [OTC]) medication.

Interactions with alcohol/food/tobacco/food

Certain medications are not recommended to be taken at or in conjunction with taking food, or eating specific kinds of food, as interactions can happen. Smoking or drinking alcohol in conjunction with certain medicines can result in interactions. Discuss with your physician the interaction of your medication in conjunction with alcohol, food, or tobacco.

Proper use of Leqvio

A nurse or another trained medical professional will administer this medication. It’s administered by injection beneath your skin, most commonly on the thighs, stomach, or upper arms.

In addition to this medication, Your doctor might also alter your diet so that it is lower in sugar, fat, and cholesterol. Be sure to follow the instructions of your physician regarding any diet that is prescribed by your doctor.

Missed dose

Consult your physician or pharmacist for directions.

Use caution when using Leqvio

It is crucial to have your doctor monitor your progress regularly to ensure that the medicine is functioning as it should. Tests for blood may be required to determine if there are any unwanted side effects.

Utilizing this medication while you are pregnant could affect your unborn child. Utilize a reliable method that prevents birth to avoid becoming pregnant while you are treated by this medication. If you suspect that you may have been pregnant while taking this medicine, notify your doctor immediately.

Do not take any other medications in the absence of discussing it with your physician. This includes non-prescription or prescription (over-the-counter OTC) medications as well as herbal or vitamin supplements.

Leqvio side effects

Alongside its necessary effects, some medicines may result in unwanted adverse effects. Although not all adverse effects can be present, if they do occur, they might require medical attention.

Consult your physician or nurse right away in the event that any of these adverse effects happen:

Less popular

  • Trouble breathing

Certain side effects can be experienced but they usually do not require medical care. These symptoms may be eliminated when the body adapts to the medication. Additionally, your health professional could be able to inform you ways to avoid or minimize the effects of these adverse effects. Consult your physician in the event that any of these adverse effects persist or are uncomfortable or if there are any concerns regarding these:

More popular

  • Bleeding, blistering chills, discoloration, bleeding skin, sensation that there is pressure itching, inflammation lumps, numbness irritation, redness, and soreness. swelling, tenderness, or tingling. or warmth around the injection site.
  • difficult to move
  • Muscle pain or stiffness
  • joint pain

Less well-known

  • Bladder pain
  • Bloody or cloudy urine
  • chest tightness
  • Mucus-producing cough
  • diarrhea
  • difficult or burning discomfort, burning, or pain during urination
  • the constant urge to urinate
  • Side or lower back or side
  • discomfort in the arms or legs

Other side effects that aren’t mentioned may occur in certain patients. If you experience any other side effects, you should consult with your physician.

Contact your physician to seek medical advice on adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

More details

Always consult your physician to confirm that the information provided on this site is appropriate to your specific situation.


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