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Jardiance (Empagliflozin)

 

Name of the generic: empagliflozin 

Brand name: Jardiance
The class of drugs: SGLT-2 inhibitors

 

What is Jardiance?

Jardiance
Jardiance

Jardiance is an oral diabetic medication which helps regulate the blood sugar level. Empagliflozin helps the kidneys to eliminate glucose from the bloodstream.

Jardiance is a combination of diet and exercise to enhance blood sugar control for those suffering from type 2 diabetes mellitus.

Jardiance helps to decrease the risk of dying due to stroke, heart attack, or heart failure among adults suffering from type 2 diabetes and who suffer from heart disease.

Jardiance also helps lower the risk of cardiovascular death and hospitalization due to the condition known as heart failure (when you have a weak heart and unable to provide enough blood flow to the other organs part of the body) for adults suffering from heart insufficiency.

Jardiance is not used to treat type 1 diabetes.

Warnings

Take a break from Jardiance and contact your doctor immediately if you experience symptoms of a serious adverse reaction that include stomach discomfort, vomiting, fatigue, or difficulty breathing.

It is not recommended to take Jardiance in the case of severe kidney disease if you are taking dialysis or if you suffer from diabetic ketoacidosis.

The use of Jardiance can cause dehydration and make you feel dizzy or weak (especially when you sit up).

Consult your physician if you are suffering from vomiting and diarrhea. Also, tell your doctor if consume less food or drink than normal.

Jardiance may cause serious infections of the vagina or penis. Get medical help immediately if you experience an itchy, burning sensation, odor or discharge, discomfort, tenderness, swelling or redness of the rectal or genital region or fever, or do not feel well.

Before taking this medication, you must consult your physician.

It is not recommended to make use of Jardiance in the event that you are allergic to empagliflozin, or you are:

  • chronic kidney diseases (or severe kidney disease if you have dialysis).

To ensure that Jardiance is suitable for you, inform your doctor if previously had:

  • kidney or liver disease;
  • an infection of the bladder or urinary tract problems;
  • a sexually transmitted disease (penis or vagina);
  • issues with your pancreas which may require surgery
  • alcoholism, or regularly consume large quantities of alcohol
  • If you’re on a diet of low salt or
  • If you’re 65 or over.

Follow the directions of your doctor regarding the use of this medication when you are pregnant or are planning to be pregnant. Controlling diabetes is essential during pregnancy.

It is not recommended to make use of Jardiance in the third or second trimester of pregnancy.

Do not breastfeed while taking Jardiance.

Jardiance is not recommended to be used by anyone younger than 18 years of age.

What way should I do to take Jardiance?

You should take Jardiance exactly as directed by your physician. Follow all instructions on the prescription label and review all medication guides or instructions sheets. Your doctor may modify your dose.

You can consume Jardiance either with food or not.

Your blood sugar level will need to be regularly checked Also, you might be required to check the amount that ketones are present in the urine. Empagliflozin is a drug that can cause ketoacidosis (too much acid in the blood). Even the blood sugar level is normal, consult your physician in the event that a urine test confirms that you have elevated ketones in the urine.

Blood sugar levels can be affected by illness, stress, or surgery alcohol consumption, not eating meals.

A low glucose level (hypoglycemia) can cause you to feel extremely dizzy, hungry, angry, and shaky. To help treat hypoglycemia fast consume or drink crackers, hard candy or raisins, juice of fruit as well as non-diet beverages. Your physician may recommend glucagon injections in the event of extreme hypoglycemia.

It’s possible to get dehydrated when you suffer from a long-term illness. Consult your doctor if have a stomach ache and diarrhea or consume less food or drink than you normally do.

This medicine may affect the results of some medical tests. Inform any physician who treats you that you’re taking Jardiance.

The treatment you receive could also include exercise, diet as well as weight management, along with specific medical treatment.

Keep at room temperature, free of heat and moisture.

Dosing information

Usual Adult Dose of Jardiance for Diabetes Type 2:

Initial dosage: 10 mg orally at least once per day in the morning
The dose may be increased to 25 mg taken orally daily for patients who tolerate therapy but needing additional glycemic control.
Maximum dose: 25 mg per day

Comments:
It is not recommended for those suffering from type I diabetes because it could cause an increase in the likelihood of diabetes ketoacidosis.
It is not recommended to improve the control of glycemic in patients with an eGFR of less than 30 mL/min/1.73 per m2 since it is not likely to be successful.
The depletion of the volume should be addressed prior to beginning treatment.

Uses:
A complement to exercise and diet to increase glycemic control people suffering from Type 2 Diabetes Mellitus.
To decrease the risk of death from cardiovascular disease in patients of adult age with the type 2 form of diabetes as well as existing cardiovascular diseases (CVD).

Usual Adult Dose for Cardiovascular Risk Reduction:

Initial dosage: 10 mg orally at least once per day in the morning
The dose may be increased to 25 mg taken orally daily for patients who tolerate therapy but who require additional glycemic management.
Maximum dose: 25 mg per day

Comments:
Not recommended for patients suffering from Type 1 Diabetes Mellitus because it could cause an increase in the likelihood of diabetes ketoacidosis.
It is not recommended to improve control of glycemic level in patients with an eGFR of less than 30 mL/min/1.73 per m2, as it is not likely to be beneficial.
Depletion of volume must be treated prior to beginning treatment.

Uses:
A supplement to exercise and diet to increase glycemic control in adults suffering from the condition of type 2 diabetes.
To decrease the risk of death from cardiovascular disease for adult patients suffering from Type 2 Diabetes Mellitus as well as already diagnosed cardiovascular disease (CVD).

The Usual Adult Dose for Heart Failure Reducing Ejection Fraction

10 mg orally every day

Comments:
Not recommended for patients suffering from Type 1 Diabetes Mellitus because it can raise the chance of diabetes ketoacidosis.
Depletion of volume must be treated prior to starting treatment.
For patients suffering from heart failure (HF) and a lower Ejection Fraction, it isn’t enough information at data to recommend the use of this drug for patients who have an eGFR of less than 20 mL/min/1.73 2 m2.

Use: To lower the chance of dying from cardiovascular disease and hospitalization for HF among patients with heart failure or decreased ejection fraction.

In-depth Jardiance dosage information

If I don’t take the dose?

You should take the medication as quickly as you can, however, avoid your missed dosage if you are nearing the time to take the next dose. Don’t take two doses at a time.

How do I react if take too much?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Help line at 1-800-222-1222.

What should I stay clear of while taking Jardiance?

Beware of drinking alcohol.

Be careful not to get up too fast from lying or sitting in a position. You could get dizzy.

Jardiance-related side effects

See a doctor immediately Get medical attention immediately if you show symptoms of an allergic reaction Jardiance such as hives, difficulty swallowing, breathing difficulties, and swelling of your lips, face tongue, throat, or face.

Get medical attention promptly if you are experiencing indications for a serious illness (penis or vagina): burning, itching discharge, odor painful, tenderness swelling or redness in the rectal or genital area or rectal area, fever, or not feeling well. The symptoms could be worsened rapidly.

Stop taking this medication and contact your doctor right away in the event that you are suffering from:

  • a euphoric feeling, similar to you’re passing out;
  • dehydration dizziness, confusion, and feeling thirsty. less urine;
  • ketoacidosis (too excessive acidity in the blood) – nausea, stomach pain, vomiting dizziness, confusion, or trouble breathing;
  • indications of a bladder infection Pain or burning while you are urinating and you have urine with blood discomfort in the pelvis or in your back.

Certain side effects are more likely to be experienced by older adults.

Common Jardiance side effects can be:

  • A bladder infection or
  • women with yeast infections (vaginal discharge or itching).

This isn’t a complete list of all side effects. other side effects could occur. Consult your physician to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

What other medications can affect Jardiance?

Other medications may enhance or reduce the effect of Jardiance in lowering blood sugar. Inform your doctor of any medications you currently take and any that you decide to start or stop taking, in particular:

  • insulin or other oral diabetes medication; or
  • diuretics or “water pill.”

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