Imitrex Injection Dosage

Generic name: sumatriptan (injection)
Brand names: Imitrex, Imitrex Statdose, SUMAtriptan Succinate Syringe, Sumavel DosePro, Zembrace SymTouch
Drug class: Antimigraine agents

Dosage forms:  TAB: 25 mg, 50 mg, 100 mg; INJ (STATdose cartridge): 4 mg per injection, 6 mg per injection; INJ (STATdose pen): 4 mg per injection, 6 mg per injection

Dosage Forms Discontinued in US

[6 mg per 0.5 mL injectable vial form not avail. as brand; see generic]

Migraine headache, acute

[PO route]

Dose: 25-100 mg PO x1; Max: 200 mg/24h; Info: may repeat dose x1 after 2h; may follow initial 4-6 mg SC dose after 1h w/ 25-100 mg PO q2h x1-2 doses, up to 100 mg/24h PO

[SC route]

Dose: 1-6 mg SC x1; Max: 6 mg/dose up to 12 mg/24h; Info: may repeat dose x1 after 1h

Cluster headache, acute

[6 mg SC x1]

Max: 6 mg/dose up to 12 mg/24h; Info: may repeat dose x1 after 1h

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[PO route]

mild-mod impairment: max 50 mg/dose PO; severe impairment: contraindicated

[SC route]

mild-mod impairment: no adjustment; severe impairment: contraindicated

Recommended Peds Dosing

Dosage forms:  INJ (STATdose cartridge): 4 mg per injection, 6 mg per injection; INJ (STATdose pen): 4 mg per injection, 6 mg per injection

Dosage Forms Discontinued in US

[6 mg per 0.5 mL injectable vial form not avail. as brand; see generic]

Migraine headache, acute

[6 yo and older]

Dose: 3-6 mg SC x1; Max: 6 mg/dose up to 12 mg/24h; Info: may repeat dose x1 after 1h

Renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

Hepatic dosing

mild-mod impairment: no adjustment; severe impairment: contraindicated