Gabitril Dosage

Generic name: tiagabine
Drug class: Gamma-aminobutyric acid reuptake inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 2 mg, 4 mg, 12 mg, 16 mg

Partial seizures, adjunct tx

[32-56 mg/day PO divided bid-qid]

Start: 4 mg PO qd x1wk, then 4 mg PO bid x1wk, then may increase. by 4-8 mg/day qwk; Max: 56 mg/day; Info: for pts receiving enzyme-inducing AED; non-induced pts require lower doses, slower titration; give w/ food; taper dose gradually to D/C

Renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]

hepatic impairment: caution advised, consider decrease. dose and/or frequency, slower titration

Recommended Peds Dosing

Dosage forms:  TAB: 2 mg, 4 mg, 12 mg, 16 mg

Partial seizures, adjunct tx

[12 yo and older]

Dose: 32 mg/day PO divided bid-qid; Start: 4 mg PO qd x1wk, then 4 mg PO bid x1wk, then may incr. by 4-8 mg/day qwk; Max: 32 mg/day; Info: for pts receiving enzyme-inducing AED; non-induced pts require lower doses, slower titration; give w/ food; taper dose gradually to D/C

Renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]

hepatic impairment: caution advised, consider decrease. dose and/or frequency, slower titration

SRC: NLM .