Eraxis Dosage

Generic name: anidulafungin
Drug class: Echinocandins

Medically reviewed by  A Ras MD

Recommended Adult Dosing

Dosage forms:  INJ

Candidemia

[100 mg IV q24h]

Start: 200 mg IV x1 on day 1; Info: treat x14 days after last positive culture

Candidiasis

[esophageal]

Dose: 200 mg IV q24h x14-21 days; Info: treat for at least 14 days and x7 days after sx resolution

[intra-abdominal, peritoneal]

Dose: 100 mg IV q24h; Start: 200 mg IV x1 on day 1; Info: duration based on source control and clinical response

[*oropharyngeal]

Dose: 100 mg IV q24h; Start: 200 mg IV x1 on day 1; Info: for fluconazole-refractory dz

[*systemic]

Dose: 100 mg IV q24h

Endocarditis, candidal

[200 mg IV q24h]

Info: for native valve endocarditis; not 1st-line agent; refer to IDSA and AHA guidelines

Renal dosing

renal impairment: no adjustment

HD: no adjustment; no supplement; PD: not defined

Hepatic dosing

[no adjustment]

Recommended Peds Dosing

Dosage forms:  INJ

Candidemia

[1 mo and older]

Dose: 1.5 mg/kg/dose IV q24h; Start: 3 mg/kg/dose IV x1 on day 1, max 200 mg/dose; Max: 100 mg/day; Info: treat x14 days after last positive culture

Candidiasis

[esophageal, 16 yo and older]

Dose: 50 mg IV q24h; Start: 100 mg IV x1 on day 1; Info: treat for at least 14 days and x7 days after sx resolution

[intra-abdominal, peritoneal, 1 mo and older]

Dose: 1.5 mg/kg/dose IV q24h; Start: 3 mg/kg/dose IV x1 on day 1, max 200 mg/dose; Max: 100 mg/day; Info: duration based on source control and clinical response

Renal dosing

renal impairment: no adjustment

HD: no adjustment; no supplement; PD: not defined

Hepatic dosing

[no adjustment]

SRC: NLM .