Encorafenib Dosage
Generic name: encorafenib
Brand name: Braftovi
Drug class: Multikinase inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 75 mg
Melanoma, unresectable or metastatic
- [450 mg PO qd]
- Info: for pts w/ BRAF V600E or V600K mutation; use w/ binimetinib; decr. dose to max 300 mg PO qd if binimetinib withheld
Colorectal CA, metastatic
- [300 mg PO qd]
- Info: for pts w/ BRAF V600E mutation; use w/ cetuximab
Renal dosing
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A: no adjustment; Child-Pugh Class B or C: not defined
SRC: NLM .