Votrient Dosage
Votrient Dosage Generic name: pazopanib Drug class: VEGF/VEGFR inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 200 mg Special Note [uses, dosing may vary] Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments; D/C >1wk before elective surgery, restart >2wk after major surgery […]
Vyzulta Dosage
Vyzulta Dosage Generic name: latanoprostene bunod ophthalmic Drug class: Ophthalmic glaucoma agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: SOL: 0.024% Elevated IOP [1 gtt in eye(s) qpm] Max: 1 dose/24h; Info: for open-angle glaucoma or ocular HTN Recommended Peds Dosing Dosage forms: SOL: 0.024% Elevated IOP [17 yo and older] Dose: 1 gtt […]
Vpriv Dosage
Vpriv Dosage Generic name: velaglucerase alfa Drug class: Lysosomal enzymes Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Restricted Distribution in US Gaucher dz, type 1 [individualize dose IV q2wk] Start: 60 units/kg/dose IV q2wk; Info: if switching from another enzyme replacement tx, start w/ previous enzyme replacement dose 2wk after last admin; consider […]
Vyxeos Dosage
Vyxeos Dosage Generic name: cytarabine and daunorubicin (liposomal) Drug class: Antineoplastic combinations Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Special Note [formulation clarification] Info: not interchangeable w/ liposomal cytarabine-containing products [uses, dosing may vary] Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose […]
Vyvanse Dosage
Vyvanse Dosage Generic name: lisdexamfetamine Drug class: CNS stimulants Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg; CHEWABLE: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg ADHD [30-70 mg PO qam] Start: 30 mg PO […]
Zokinvy Dosage
Zokinvy Dosage Generic name: lonafarnib Drug class: Miscellaneous metabolic agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 50 mg, 75 mg Hutchinson-Gilford progeria syndrome [150 mg/m^2/dose PO bid] Start: 115 mg/m^2/dose PO bid x4mo, then incr. to 150 mg/m^2/dose PO bid as tolerated; Info: round dose to nearest 25 mg increment; give w/ […]
Zolinza Dosage
Zolinza Dosage Generic name: vorinostat Drug class: Histone deacetylase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 100 mg Special Note [uses, dosing may vary] Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, and dosing incl. toxicity-related dose adjustments Cutaneous T-cell lymphoma, refractory [400 mg PO qd] […]
Zolpimist Dosage
Zolpimist Dosage Generic name: zolpidem oral spray, metered Drug class: Miscellaneous anxiolytics, sedatives and hypnotics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: SPRAY: 5 mg per actuation Insomnia, short-term tx [female pts] Dose: 5 mg PO qhs; Max: 10 mg/day; Info: for sleep onset; use lowest effective dose, shortest possible tx duration; give […]
Zyclara Dosage
Zyclara Dosage Generic name: imiquimod topical Drug classes: Topical anti-infectives, Topical antineoplastics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CRM: 2.5%, 3.75% Condyloma acuminata, external [apply 3.75% qhs] Max: 8wk; Info: apply until total clearance or max duration; leave on x8h; 1st-line agent Actinic keratosis [apply qhs x2wk, off x2wk] Max: 2 pkts/application or 2 […]
MUTAMYCIN SIDE EFFECTS
MUTAMYCIN SIDE EFFECTS Generic Name: mitomycin Brand Name: Mutamycin Drug Class: Antineoplastics, Antibiotic, Antineoplastics, Antibiotic Last updated on MDtodate: 10/7/2022 SIDE EFFECTS Bone Marrow Toxicity: This was the most common and most serious toxicity, occurring in 605 of 937 patients (64.4%). Thrombocytopenia and/or leukopenia may occur anytime within 8 weeks after onset of therapy with an average time of 4 weeks. Recovery after cessation […]