Votrient Dosage

Generic name: pazopanib
Drug class: VEGF/VEGFR inhibitors

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 200 mg

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments; D/C >1wk before elective surgery, restart >2wk after major surgery when wound fully healed

Renal cell CA, advanced

[800 mg PO qd]
Info: give at least 1h before or 2h after meals; do not cut/crush/chew tab

Soft tissue sarcoma, advanced

[800 mg PO qd]
Info: for pts w/ previously treated dz; give at least 1h before or 2h after meals; do not cut/crush/chew tab

Renal dosing

renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
bilirubin 1.6-3x ULN and any ALT: 200 mg qd; bilirubin >3x ULN and any ALT: avoid use

 

SRC: NLM .