Darzalex Dosage
Darzalex Dosage Generic name: daratumumab Drug class: CD38 monoclonal antibodies Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Multiple myeloma, newly diagnosed [autologous HSCT ineligible, combo w/ bortezomib, melphalan, and prednisone] Dose: 16 mg/kg/dose IV qwk x6 doses, then starting wk 7, give 16 mg/kg/dose IV q3wk x16 doses, then starting wk […]
Darzalex Faspro Dosage
Darzalex Faspro Dosage Generic name: daratumumab and hyaluronidase Drug class: CD38 monoclonal antibodies Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ: 120 mg/2000 units per mL Multiple myeloma, newly diagnosed [autologous HSCT ineligible, combo w/ bortezomib, melphalan, and prednisone] Dose: 1800 mg/30,000 units SC qwk x6 doses, then starting wk 7, give 1800 mg/30,000 units […]
Dasatinib Dosage
Dasatinib Dosage Generic name: dasatinib Brand name: Sprycel Dosage form: oral tablet (100 mg; 140 mg; 20 mg; 50 mg; 70 mg; 80 mg) Drug class: BCR-ABL tyrosine kinase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 20 mg, 50 mg, 70 mg, 80 mg, 100 mg, 140 mg CML, Ph-positive [chronic phase, newly […]
Daurismo Dosage
Daurismo Dosage Generic name: glasdegib Drug class: Hedgehog pathway inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 25 mg, 100 mg AML, newly diagnosed [100 mg PO qd on days 1-28 of 28-day cycle] Info: for pts 75 yo and older, or who are ineligible for intensive induction chemo d/t comorbidities; use […]
Daytrana Dosage
Daytrana Dosage Generic name: methylphenidate (transdermal) Brand name: Daytrana Drug class: CNS stimulants Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: PATCH: 10 mg per 9h, 15 mg per 9h, 20 mg per 9h, 30 mg per 9h ADHD [apply 1 patch qd x9h, off x15h] Start: apply 10 mg patch qd x9h, off x15h; […]
Dayvigo Dosage
Dayvigo Dosage Generic name: lemborexant Dosage form: Tablets Drug class: Miscellaneous anxiolytics, sedatives and hypnotics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 5 mg, 10 mg Insomnia [5 mg PO qhs] Max: 10 mg/day; Info: for sleep onset and/or maintenance; use lowest effective dose; give immediately before bedtime and >7h before planned awakening; […]
DDAVP Dosage
DDAVP Dosage Generic name: desmopressin (nasal) Brand names: DDAVP Nasal, DDAVP Rhinal Tube, Noctiva, Stimate Drug class: Antidiuretic hormones Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 0.1 mg, 0.2 mg; INJ: various Diabetes insipidus, central [PO route] Dose: 0.1-1.2 mg/day PO divided bid-tid; Start: 0.05 mg PO bid; Max: 1.2 mg/day; Info: give 1st PO dose […]
Dactinomycin Dosage
Dactinomycin Dosage Generic name: dactinomycin Brand name: Cosmegen Drug class: Antibiotics / antineoplastics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Wilms tumor [45 mcg/kg/dose IV q3-6wk for up to 26wk] Info: part of multi-drug chemo regimen Rhabdomyosarcoma [15 mcg/kg/dose IV qd x5 days q3-9wk for up to 112wk] Info: part of multi-drug […]
Dalbavancin Dosage
Dalbavancin Dosage Generic name: dalbavancin Brand name: Dalvance Drug class: Glycopeptide antibiotics Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Skin/skin structure infections, acute bacterial [1500 mg IV x1] Alt: 1000 mg IV x1, then 1wk later, 500 mg IV x1 Renal dosing [one-dose regimen] CrCl <30: 1125 mg x1 HD: no adjustment; no […]
Dalfampridine Dosage
Dalfampridine Dosage Generic name: dalfampridine Brand name: Ampyra Drug class: Miscellaneous central nervous system agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: ER TAB: 10 mg Multiple sclerosis [10 mg PO q12h] Max: 20 mg/day; Info: do not cut/crush/chew/dissolve tab Renal dosing [see below] CrCl 51-80: caution advised; CrCl <51: contraindicated HD/PD: not […]