Inlyta Dosage
Inlyta Dosage Generic name: axitinib Drug classes: Multikinase inhibitors, VEGF/VEGFR inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 1 mg, 5 mg Renal cell CA, advanced [first-line tx, combo w/ avelumab] Dose: 5-10 mg PO q12h; Start: 5 mg PO q12h for at least 2wk, if normotensive w/o receiving antihypertensive, and no […]
Injectafer Dosage
Injectafer Dosage Generic name: ferric carboxymaltose Drug class: Iron products Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Iron deficiency anemia [<50 kg] Dose: 15 mg/kg/dose IV x2 doses >7 days apart; Info: for pts w/ non-dialysis dependent CKD or unable to take PO form; may repeat tx course if recurrent iron […]
Inbrija Dosage
Inbrija Dosage Generic name: levodopa inhalation capsules Drug class: Dopaminergic antiparkinsonism agents Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: DPI: 42 mg per cap Parkinson disease, adjunct tx [2 caps inhaled 1-5x/day prn] Max: 2 caps/dose, 5 doses/day; Info: use w/ carbidopa/levodopa; caps for use w/ Inbrija inhaler only; taper dose gradually to […]
Increlex Dosage
Increlex Dosage Generic name: mecasermin Drug class: Insulin-like growth factors Medically reviewed by A Ras MD. Recommended Peds Dosing Dosage forms: INJ: 10 mg per mL Primary IGFD, severe [2 yo and older] Dose: 0.04-0.12 mg/kg/dose SC bid; Start: 0.04-0.08 mg/kg/dose SC bid x1wk, incr. by 0.04 mg/kg/dose; Max: 0.24 mg/kg/day; Info: not a substitute for GH […]
Ilaris Dosage
Ilaris Dosage Generic name: canakinumab Drug class: Interleukin inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ: 150 mg per mL Cryopyrin-assoc. periodic syndromes [<41 kg] Dose: 2 mg/kg/dose SC q8wk [>41 kg] Dose: 150 mg SC q8wk TNF receptor-assoc. periodic syndrome [<41 kg] Dose: 2 mg/kg/dose SC q4wk; Info: may incr. to […]
Iloprost Dosage
Iloprost Dosage Generic name: iloprost inhalation Brand name: Ventavis Dosage form: inhalation solution (10 mcg/mL; 20 mcg/mL) Drug class: Agents for pulmonary hypertension Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: NEB: 10 mcg per mL, 20 mcg per mL Restricted Distribution in US Pulmonary arterial HTN [5 mcg NEB 6-9x/day] Start: 2.5 mcg NEB x1; Max: […]
Ilumya Dosage
Ilumya Dosage Generic name: tildrakizumab Drug class: Interleukin inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ (pre-filled syringe): 100 mg per mL Psoriasis, mod-severe plaque [100 mg SC q12wk] Start: 100 mg SC x1 on wk 0, 4 Renal dosing [not defined] renal impairment: not defined HD/PD: not defined Hepatic dosing […]
Imatinib Dosage
Imatinib Dosage Generic name: imatinib Brand name: Gleevec Dosage form: oral tablet (100 mg; 400 mg) Drug class: BCR-ABL tyrosine kinase inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: TAB: 100 mg, 400 mg Special Note Ph-positive CML [chronic phase, newly diagnosed] Dose: 400 mg PO qd; Info: may incr. dose to 600 mg PO […]
Imbruvica Dosage
Imbruvica Dosage Generic name: ibrutinib Drug class: BTK inhibitors Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: CAP: 70 mg, 140 mg; TAB: 140 mg, 280 mg, 420 mg, 560 mg Mantle cell lymphoma, relapsed or refractory [560 mg PO qd] Info: do not open cap; do not cut/crush/chew tab CLL/SLL [420 mg […]
Fabrazyme Dosage
Fabrazyme Dosage Generic name: agalsidase beta Drug class: Lysosomal enzymes Medically reviewed by A Ras MD. Recommended Adult Dosing Dosage forms: INJ Fabry disease [1 mg/kg/dose IV q2wk] Info: premed w/ antipyretic, consider antihistamine, corticosteroid Renal dosing [not defined] renal impairment: not defined HD/PD: not defined Hepatic dosing [not defined] Recommended Peds Dosing Dosage forms: INJ Fabry disease [2 […]