Zykadia Dosage

Generic name: ceritinib
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  CAP: 150 mg; TAB: 150 mg

Non-small cell lung CA, metastatic

[ALK-positive dz]
Dose: 450 mg PO qd; Info: give w/ food
[*ROS1-positive dz]
Dose: 450 mg PO qd; Info: give w/ food

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
Child-Pugh Class C: decr. dose 33%

 

SRC: NLM .