Zulresso Dosage
Generic name: brexanolone
Drug class: Miscellaneous antidepressants
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Restricted Distribution in US
Postpartum depression
- [30 mcg/kg/h IV x4h, then 60 mcg/kg/h IV x20h, then 90 mcg/kg/h IV x28h, then 60 mcg/kg/h IV x4h, then 30 mcg/kg/h IV x4h]
- Info: may decr. 90 mcg/kg/h IV x28h to 60 mcg/kg/h IV x28h if not tolerated
Renal dosing
- eGFR <15: avoid use
- HD/PD: not defined
Hepatic dosing
- [no adjustment]
SRC: NLM .