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  • Generic Name: acyclovir ointment
  • Brand Name: Zovirax Ointment
  • Drug Class: Antivirals, Topical
Last updated on MDtodate: 10/03/2022


In the controlled clinical trials, mild pain (including transient burning and stinging) was reported by about 30% of patients in both the active and placebo arms;treatment was discontinued in two of these patients. Local pruritus occurred in 4% of these patients. In all studies, there was no significant difference between the drugand placebo group in the rate or type of reported adverse reactions nor were there any differences in abnormal clinical laboratory findings.

Observed During Clinical Practice

Based on clinical practice experience in patients treated with ZOVIRAX Ointment in the U.S., spontaneously reported adverseevents are uncommon. Data are insufficient to support an estimate of their incidence or to establish causation. These events may also occur as part of the underlyingdisease process. Voluntary reports of adverse events that have been received since market introduction include:

General: Edema and/or pain at the application site.

Skin: Pruritus, rash.




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