Zepzelca Dosage

Generic name: LURBINECTEDIN .5mg in 1mL
Dosage form: injection, powder, lyophilized, for solution
Drug class: Alkylating agents

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  INJ

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, concomitant meds to mitigate toxicity, and dosing incl. toxicity-related dose adjustments

Small cell lung CA, metastatic

[3.2 mg/m^2/dose IV q21 days]
Info: for pts w/ progressive dz on or after platinum-containing chemo

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

bilirubin 1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN and any AST: not defined

 

SRC: NLM .