Xyrem Dosage

Generic name: sodium oxybate
Drug class: Miscellaneous anxiolytics, sedatives and hypnotics

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: SOL: 0.5 g per mL

[6-9 g/day PO divided bid]

Start: 2.25 g PO bid, incr. 1.5 g/day qwk; Max: 9 g/day; Info: give 1st dose in bed at hs, 2nd dose 2.5-4h later; give at least 2h after meal

renal impairment: not defined, caution advised

HD/PD: not defined

[adjust dose amount]

hepatic impairment: decr. start dose 50%, titrate to effect

SRC: NLM .