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Xcopri Dosage

Generic name: cenobamate
Dosage form: Tablets
Drug class: Carbamate anticonvulsants

Medically reviewed by  A Ras MD.


 Recommended Adult Dosing

Dosage forms:  TAB: 12.5 mg, 25 mg, 50 mg, 100 mg, 150 mg, 200 mg

Partial seizures

[200 mg PO qd]
Start: 12.5 mg PO qd x2wk, then 25 mg PO qd x2wk, then 50 mg PO qd x2wk, then incr. by 50 mg/day q2wk until 200 mg PO qd, then may incr. by 50 mg/day q2wk; Max: 400 mg/day; Info: do not crush/chew tab; taper dose gradually over >2wk to D/C

Renal dosing

[see below]
renal impairment: consider decr. usual dose
HD/PD: not defined

Hepatic dosing

Child-Pugh Class A or B: consider decr. usual dose, max 200 mg/day; Child-Pugh Class C: avoid use



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