Xcopri Dosage
Generic name: cenobamate
Dosage form: Tablets
Drug class: Carbamate anticonvulsants
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 12.5 mg, 25 mg, 50 mg, 100 mg, 150 mg, 200 mg
Partial seizures
- [200 mg PO qd]
- Start: 12.5 mg PO qd x2wk, then 25 mg PO qd x2wk, then 50 mg PO qd x2wk, then incr. by 50 mg/day q2wk until 200 mg PO qd, then may incr. by 50 mg/day q2wk; Max: 400 mg/day; Info: do not crush/chew tab; taper dose gradually over >2wk to D/C
Renal dosing
- [see below]
- renal impairment: consider decr. usual dose
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: consider decr. usual dose, max 200 mg/day; Child-Pugh Class C: avoid use
SRC: NLM .