Wellbutrin SR Dosage

Generic name: bupropion
Brand names: Aplenzin, Forfivo XL, Wellbutrin SR, Wellbutrin XL, Zyban Advantage Pack
Drug class: Miscellaneous antidepressants

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  ER TAB: 100 mg, 150 mg, 200 mg

Major depressive disorder

[150 mg PO bid]

Start: 150 mg PO qam, incr. after 3 days; Max: 400 mg/day; Info: do not cut/crush/chew tab

Smoking cessation

[150 mg PO bid x7-12wk]

Start: 150 mg PO qd x3 days; Max: 300 mg/day; Info: separate doses by at least 8h; last dose no later than 6pm; stop smoking after 5-7 days of tx; do not cut/crush/chew tab

ADHD

[200 mg PO qam, 100 mg PO qpm]

Start: 100 mg PO qam, incr. 100 mg/day qwk, divide dose bid; Max: 400 mg/day; Info: do not cut/crush/chew tab

Renal dosing

[see below]

renal impairment: consider decr. usual dose and/or frequency; Info: ER form cannot be cut, consider IR form for dose adjustments

HD/PD: not defined, caution advised

Hepatic dosing

[adjust dose amount, frequency]

Child-Pugh Class A: consider decr. dose freq and/or amt; Child-Pugh Class B or C: max 100 mg/day or 150 mg q48h

SRC: NLM .